Zygomycosis: A potentially fatal, dangerous infection that is caused by various fungi from the class Zygomycetes. Zygomycosis is seen most often in patients who are already ill with diseases that suppress the immune system, such as AIDS, burn patients, patients taking corticosteroids, and those with poorly controlled diabetes. If unchecked, the fungal infection can spread to the lungs and other organs, the blood, the eyes, and the brain. Treatment involves controlling the underlying condition and attacking the infection with antifungal medications.
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