Why Do I Feel So Sick on Ozempic?

Medically Reviewed on 10/5/2022
How does Ozempic work?
Ozempic is either used alone or combined with other diabetes medications.

Ozempic is a glucagon-like peptide-1 receptor agonist (GLP-1RA) that slows down stomach emptying. It may present with mild to moderate stomach upset and nausea. These symptoms could be temporary and last for a few weeks.

To relieve indigestion symptoms, eat smaller portions of foods throughout the day.

Common digestive problems with the usage of Ozempic are burping as a response to acid reflux and indigestion.

How does Ozempic work?

Semaglutide acts similarly to glucagon-like peptide-1, a hormone produced in the intestine by increasing the insulin level produced by the pancreas in response to food intake. This helps regulate blood glucose levels.

Ozempic is either used alone or combined with other diabetes medications, such as:

4 facts about Ozempic

  1. Active ingredients: Semaglutide
  2. Drug class: Ozempic is a glucagon-like peptide-1 receptor agonist (GLP-1RA)
  3. Drug form: Liquid solution for subcutaneous injection
  4. FDA approval: 2017

What are the uses of Ozempic?

Ozempic is either used alone or combined with other medication for diabetes. It is particularly used to treat type II diabetes.

A few studies have reported that Ozempic helps reduce blood sugar levels and aid in weight loss.

Ozempic is available as a pen injector for subcutaneous (under the skin) injections.

The subcutaneous Ozempic is used for:

  • Type II diabetes: Ozempic treats type II diabetes by regulating blood sugar levels. Ozempic is recommended for adults with type II diabetes and cardiovascular diseases because it lowers the risk of heart attack, stroke, and death in such people. 
  • Weight loss: This subcutaneous drug decreases the appetite, and many people with type II diabetes who take this drug lose weight. Ozempic is not FDA approved for weight management. However, some doctors prescribe it off-label for weight management.

What are the side effects of Ozempic?

The side effects of Ozempic could be temporary and last only a few weeks. If symptoms do not fade away after a few weeks and bother you, immediately consult your doctor.

Here are the common side effects of Ozempic.

Mild side effects of Ozempic

This list may not include all the possible side effects.

Serious side effects of Ozempic


______________ is another term for type 2 diabetes. See Answer

What should be the dosage of Ozempic?

Ozempic solution is available as pen injectors.

  • A weekly injection is administered subcutaneously on the abdomen, thigh, or upper arm.
  • Initially, the dose is 0.25 mg one time a week. After four weeks, the dose may be increased based on the glycemic targets.
  • The dose is generally not increased beyond 2 mg per week.
  • Carefully follow the medical treatment, diet, and exercise plan as instructed by your physician.

What are the safety measures to be taken while using Ozempic?

Consider the following before using Ozempic:

  • Allergy to semaglutide or any other medication in the same drug group as Ozempic
  • Any history of medullary thyroid cancer in the family
  • Have type I diabetes
  • Call a doctor if there are any changes in your vision after using Ozempic
  • Have pancreatitis
  • Tell your doctor if you have preexisting kidney, liver, or gall bladder disease before using Ozempic
  • Identify any serious side effects of Ozempic
  • Tell your doctor if you are pregnant or planning to be pregnant before taking Ozempic
  • Do not use different brands of semaglutide at the same time
  • Use medication regularly, every seven days, to get the possible benefits
  • Never share an injection pen with others
Medically Reviewed on 10/5/2022
Image Source: iStock image

Ozempic: What Is It and How to Use It. https://tcoyd.org/2018/03/https-tcoyd-org-2018-03-ozempic/

Ozempic Pen Injector - Uses, Side Effects, and More. https://www.webmd.com/drugs/2/drug-174491/ozempic-subcutaneous/details

Ozempic 0.25 mg solution for injection in pre-filled pen. https://www.medicines.org.uk/emc/product/9748/smpc#gref