
Most miscarriages occur in the first trimester before the 12th week of pregnancy. A miscarriage in the second trimester (between 13 and 19 weeks) happens in 1% to 5% of pregnancies.
Early first-trimester pregnancy loss is defined as a nonviable intrauterine pregnancy with either an empty gestational sac or a gestational sac containing an embryo or a fetus without fetal heart activity within the first six to seven weeks of pregnancy. This means that a miscarriage may occur if pregnancy fails to progress due to either an empty gestational sac or a lack of fetal heart activity in an embryo. The incidence of a miscarriage in the first six weeks is as high as 31%.
- The risk of a miscarriage decreases by 10% after the pregnancy crosses six weeks. Once fetal heart activity is established after six weeks, there is a decreased chance of failed pregnancy.
Early second-trimester pregnancy loss or late miscarriages occur after 13 and before 20 weeks of pregnancy. The incidence of second-trimester pregnancy loss is less than 1%.
Stillbirth or fetal death: Pregnancy loss that occurs at or after 20 weeks of pregnancy or at a weight of 350 grams (about ¾ of a pound) or greater is generally referred to as a stillbirth or fetal death. The approximate rate of stillbirth in the United States is 6 per 1,000 live births and stillbirths.
What is a miscarriage?

The loss of a baby within the first 20 weeks of pregnancy is called a miscarriage. When the unborn baby's weight is less than 400 grams and the baby dies, it is also considered a miscarriage. About 10% to 20% of known pregnancies end in a miscarriage; however, the actual figure may be higher. About 75% of women who have had three or four miscarriages will go on to have a successful pregnancy later.
A doctor or nurse may refer to a miscarriage as a spontaneous abortion. Abortion is a common medical name for all pregnancies that end before 20 weeks.
- If a miscarriage occurs in the first 12 to 14 weeks of pregnancy, it’s referred to as an early miscarriage.
- If pregnancy loss occurs after 14 weeks and up to 20 weeks of pregnancy, it’s referred to as a late miscarriage.

SLIDESHOW
16 Early Signs & Symptoms of Pregnancy: Could You Be Pregnant? See SlideshowWhat are the common causes of a miscarriage?
As per research, most early miscarriages are caused by abnormal chromosomes (structures that contain genetic information that we inherit from parents) of the developing baby (fetus) in the womb. It is common when the mother is older than 35. This means that women over the age of 35 years old who are having children are more likely to have a miscarriage. If the partner is older thane 45, the mother is more likely to have a miscarriage. Below are a few other causes of a miscarriage
- Smoking
- Consuming alcohol
- Using recreational drugs
- Consuming high amounts of caffeine
- Being overweight
- Maternal- or paternal-side reproduction problems
- Having fertility problems or taking a long time to conceive
- Having any abnormalities of the uterus (womb) or cervix (weakness of the neck of the womb)
- Having certain medical conditions (systemic lupus erythematosus)
- Having diabetes mellitus that is not well controlled
- Having particular infections such as German measles (rubella)
Factor V Leiden: This blood-clotting genetic mutation has been found in studies to result in a lower live birth rate.
- Even after three miscarriages in a row, more than 7 women out of every 10 will not have a miscarriage the next time around.
Other major and possible causes of a miscarriage include
Chromosomal abnormalities are one of the major causes of a miscarriage. Other causes include:
- Maternal age
- Uterine abnormalities
- Hormonal irregularities
- Infections such as herpes, syphilis, or listeriosis
- Incompetent cervix (cervix dilates too early during pregnancy without pain or contractions)
- Improper implantation of the fertilized egg in the uterine lining
- Blighted ovum (embryo implants in the uterus but doesn’t develop into a baby)
- Intrauterine fetal demise (embryo stops developing and dies)
- Molar pregnancy (tissue in the uterus forms into a tumor)
- Translocation (when part of a chromosome moves to another chromosome)
- Septate uterus (band of muscle called septum divides the uterus into two sections)
- Asherman syndrome (scars in the uterus that can damage the lining of the uterus)
Health News
- After Salmonella Cases Double in a Week, Cantaloupe Recall Expanded
- COVID Vaccines Curbed Pandemic-Linked Surge in Preemie Births
- Could a 'Brain Coach' Help Folks at Higher Risk for Alzheimer's?
- Early Promise for Stem Cell Therapy to Curb MS
- Internet Poses No Threat to Mental Health, Major Study Finds
More Health News »
Who is at a risk for a miscarriage? 18 Factors
18 Factors that may increase the risk of a miscarriage include
- History of two or more previous miscarriages
- Over the age of 35 years old
- Smoking
- Drinking alcohol
- Drug abuse
- Being exposed to harmful chemicals
- Autoimmune disorders such as systemic lupus erythematosus
- Obesity
- Hormonal problems such as polycystic ovarian syndrome (PCOS)
- Preexisting diabetes
- Thyroid problems
- Prenatal tests such as amniocentesis or chorionic villus sampling
- Caffeine consumption
- Congenital heart disease
- Severe kidney disease
- Severe malnutrition
- Radiation
- Certain medications such as Accutane (isotretinoin)
What are the signs and symptoms of a miscarriage?
Most women, especially during early pregnancy, will experience a miscarriage that is similar to heavy periods with slightly more cramping and bleeding than usual. It’s also common to have vaginal bleeding and pass large blood clots up to the size of a lemon. Heavy miscarriage bleeding can be scary or surprising, but it’s usually normal. Below are the common signs and symptoms of a miscarriage
- Vaginal bleeding or spotting
- Dull lower back pain/pressure
- Cramping
- Changes to vaginal discharge
- Passage of larger-than-usual-size clots
- No longer experiencing pregnancy symptoms such as feeling sick and breast tenderness
Call the physician if you observe these symptoms of infection after a miscarriage
If there is a fever or severe abdominal pain, the abortion may become septic (infection of the cells of the uterus). This condition is a medical emergency.
How is a miscarriage usually treated?
Once a pregnancy has ended, there is nothing that can be done to prevent miscarriage from occurring.
- Natural: Many women prefer to wait for the miscarriage to occur naturally. An incomplete miscarriage should happen within a week. A missed miscarriage may take longer to begin naturally (three to four weeks).
- Medication: Women may prefer to take medication to ensure the miscarriage happens sooner rather than later. An incomplete miscarriage will usually be passed within six to eight hours of taking the medication. A missed miscarriage can happen quickly or may not happen for a few weeks. There are side effects that can occur with the medication, such as nausea and vomiting, chills, fever, and diarrhea. These effects usually only last for a few hours but can be distressing.
- Surgery: In rare cases, women need surgery to remove the pregnancy tissue (called a dilation and curettage or D&C). This may happen in the case of a missed miscarriage if there is severe bleeding and pain or if the patient's preference is to avoid medication and they don’t wish to wait for a miscarriage to begin naturally. A surgery called D&C happens under general anesthesia and the surgery happens through the vagina. Like all surgical procedures, there are some risks involved such as infection, heavy bleeding (retained pregnancy tissue), damage to the cervix, and risks associated with anesthesia.
Patients may also be advised to take
- Tylenol (acetaminophen) for cramps
- Water for hydration
- A balanced diet that is high in iron and vitamin C. Patients may be low in iron because of blood loss. Foods rich in iron include red meat, shellfish, eggs, beans, and leafy green vegetables. Foods high in vitamin C include citrus fruits, tomatoes, and broccoli. Doctors may also prescribe iron pills or a multivitamin.
- Counseling in some cases
Subscribe to MedicineNet's Pregnancy & Newborns Newsletter
By clicking "Submit," I agree to the MedicineNet Terms and Conditions and Privacy Policy. I also agree to receive emails from MedicineNet and I understand that I may opt out of MedicineNet subscriptions at any time.
Health Solutions From Our Sponsors
March of Dimes
Cleveland Clinic
ACOG
Medscape Medical Reference
HealthLinkBC
Mayo Clinic
Top What Week Is the Highest Risk of a Miscarriage Related Articles
What Are the Chances of Successful Pregnancy After Miscarriage?
Your body may require anywhere from a few weeks to over a month to recover from a miscarriage. The pregnancy hormones remain in your blood for up to two months. You should expect to get your period four to six weeks after miscarriage.How Can I Avoid Miscarriage?
A miscarriage cannot always be prevented, but there are steps you can take to lower your risk. Learn about what you can do to reduce your risk of pregnancy loss and check out the center below for more medical references on pregnancy, including multimedia (slideshows, images, and quizzes), related diseases, treatment, diagnosis, medications, and prevention or wellness.How Do You Know if You Have Had a Miscarriage?
What is a miscarriage, and how do you know if you have had one? Learn the signs of a miscarriage and what to do if you suspect that you might be having a miscarriage.How Long Does a Hysteroscopy Take?
Hysteroscopy is a procedure performed by a gynecologist to inspect inside of the uterine cavity using a thin tube with a light and camera attached to it. Hysteroscopy can take anywhere between 5 to 30 minutes or longer if a surgical procedure is being performed at the same time. Surgical procedures to treat uterine pathologies can take between 30 minutes to 2 hours as well, depending on the procedure.How Long Does a Miscarriage Last?
A miscarriage is the loss of a pregnancy within the first 20 weeks of conceiving. It’s also called pregnancy loss or spontaneous abortion. Every miscarriage is different, and the experience varies from person to person.How to Prevent Miscarriage
While not all miscarriages have known causes, adopting certain habits before and during pregnancy may help prevent miscarriage.Is It Easier To Get Pregnant After Miscarriage?
A miscarriage is broadly defined as any spontaneous loss of a pregnancy. It may be best to try to get pregnant in three to twelve months after a pregnancy.mifepristone
Mifepristone (Mifeprex) is a synthetic steroid used to terminate early pregnancy. The Korlym brand of mifepristone is a cortisol receptor blocker, used to manage and treat high blood glucose levels (hyperglycemia) in people with Cushing’s syndrome. Serious and sometimes fatal infections and bleeding occur very rarely. A failed pregnancy termination could cause birth defects. Common side effects include abdominal pain and cramping, uterine cramping, nausea, fatigue, headache, vomiting, diarrhea, dizziness, endometrial hypertrophy, low blood potassium (hypokalemia), joint pain (arthralgia), swelling of extremities (peripheral edema), and others.Miscarriage
Miscarriage is the medical term for the spontaneous loss of pregnancy from conception to 20 weeks gestation. Risk factors for a woman having a miscarriage include cigarette smoking, older maternal age, radiation exposure, previous miscarriage, maternal weight, illicit drug use, use of NSAIDs, and trauma or anatomical abnormalities to the uterus. There are five classified types of miscarriage: 1) threatened abortion; 2) incomplete abortion; 3) complete abortion; 4) missed abortion; and (5 septic abortion. While there are no specific treatments to stop a miscarriage, a woman's doctor may advise avoiding certain activities, bed rest, etc. If a woman believes she has had a miscarriage, she needs to seek prompt medical attention.
raspberry leaf
Raspberry leaf is an herbal product used by pregnant women as a uterine tonic to ease labor and delivery. Suggested uses of raspberry leaf include painful menstruation (dysmenorrhea), excessively heavy menstruation (menorrhagia), prevention of miscarriage, alleviation of morning sickness, diarrhea, and others. There are no reported side effects of raspberry leaf. Overdose of raspberry leaf may cause vomiting and diarrhea. Do not take raspberry leaf during the first trimester of pregnant. Consult your doctor if breastfeeding.What Does a Miscarriage at 5 Weeks Feel Like?
Miscarriage at 5 weeks may often go unnoticed or feel like a heavier period, including symptoms such as vaginal bleeding or discharge.What Is the Best Treatment After Miscarriage?
Dilation and curettage (D&C) is the most common surgical procedure performed for incomplete miscarriage, involving removing the contents of the fetus and other tissues.