What Medication Is Best for Sinusitis?

Medically Reviewed on 5/20/2022
What Medication Is Best for Sinusitis
Medications for sinusitis vary depending on the severity of the condition

Sinusitis occurs when the tissues lining the sinus cavities get swollen as a result of an inflammatory reaction or a viral, bacterial, or fungal infection. 

Medications and treatment for sinusitis vary depending on the severity of the condition.

What medications are used to treat mild, severe, and chronic sinusitis?

Mild to moderate sinusitis

If the sinus congestion is mild, it can be relieved with medications such as:

Severe sinusitis

If symptoms do not improve after 10 days, treatments may change to:

  • Antibiotics
  • Oral or topical decongestants
  • Prescription intranasal steroid sprays

Chronic sinusitis

Chronic sinusitis is often treated by focusing on the underlying condition (which are typically allergies):

When sinusitis is not controlled with these treatments, a computed tomography scan may be taken to have a better look at the sinuses. Based on the results, surgery may be required to correct structural problems in the sinuses. This is often advised in the case of polyps and fungal infections.

What are different types of sinusitis?

  • Acute sinusitis: Symptoms last for 4 weeks or less and may be due to bacterial or viral infections or allergies.
  • Chronic sinusitis: Sinus swelling lasts for more than 3 months and may be due to bacterial or fungal infections.
  • Subacute sinusitis: Sinus congestion lasts for 1-3 months.

What causes sinusitis?

The sinuses are air-filled cavities in the skull that are located behind the forehead, nasal bones, cheeks, and eyes. They produce thin mucus that drains out of the nose and keeps the nasal passages clear of germs and allergens.

When these sinus openings are blocked and traps mucus and air inside the sinuses, germs can grow more easily and cause infection.

Causes of sinusitis include:

  • Medical conditions where small hair-like structures (cilia) present in the sinuses fail to properly drain mucus.
  • Colds and allergies, which lead to too much mucus production or block the sinus cavities.
  • Deviated nasal septum, nasal bone spurs, or nasal polyps that block the sinus cavities.

What are risk factors for sinusitis?

Risk factors for sinusitis include:

  • Respiratory tract infections
  • Seasonal allergies
  • Allergies to dust, pollen, and pet dander
  • Nasal polyps that can lead to obstruction and inflammation
  • Weakened immune system due to human immunodeficiency virus or chemotherapy
  • Abnormal sinus structures, such as deviated septum


Common Allergies: Symptoms and Signs See Slideshow

What are symptoms of sinusitis?

Symptoms vary depending on the severity of the condition and may include:

What complications are associated with sinusitis?

Although rare, untreated sinus infections can become dangerous if they lead to infection of the brain, eyes, or surrounding bones. This can cause conditions such as:

Medically Reviewed on 5/20/2022
Image Source: iStock Image

Brook I. Acute Sinusitis. Medscape. https://emedicine.medscape.com/article/232670-overview

Brook I. Chronic Sinusitis. Medscape. https://emedicine.medscape.com/article/232791-overview