
Cisapride is a medication used to treat heartburn in people with gastroesophageal reflux disease. Because of its potential side effects, cisapride should only be used under the supervision of a doctor, when all other medications have failed.
What is cisapride?
Cisapride is a gastroprokinetic drug, which improves the motility of the upper gastrointestinal tract and is used to treat constipation. The drug has been banned since August 2000.
- Many countries have limited the usage of cisapride due to its various side effects.
- There are many other alternatives and safe medications that work similarly to cisapride.
How is cisapride taken?
Cisapride is taken orally on an empty stomach at least 15 minutes before eating and bedtime.
Inform your pediatrician before giving it to children. Special care has to be taken when cisapride is given to children.
Take cisapride as directed by your doctor. If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for the next dose, skip the missed dose and take it at the next scheduled time, then resume your regular dosing schedule.
It is advised to take ECG and renal function tests before taking this medication.
What are the uses of cisapride?
Cisapride has very few benefits, such as:
- Increases bowel movements and is used to treat heartburn
- Treats constipation
- Used to treat vomiting
What are the side effects of cisapride?
Common side effects include:
- Diarrhea
- Stomach upset
- Stomach pain
- Headache
- Stuffy nose
- Constipation
- Cough
- Drowsiness
Some of the side effects where you may need medical attention include:
Rare side effects include:
- Confusion
- Depression
- Hallucinations
- Seizures
- Vision problems
- Allergic reactions, such as angioedema
- Abnormal heart rhythm
- Chest pain
- Complete stoppage of the heart

QUESTION
Pancreatitis is inflammation of an organ in the abdomen called the pancreas. See AnswerWhat are the precautions to be taken before taking cisapride?
Cisapride should be taken only under a doctor's prescription. Inform your doctor if you have any of the following conditions:
- Any eating disorders such as anorexia or bulimia nervosa
- Any heart diseases or heart conditions, such as problems in the heart's valves or irregular heartbeat
- Kidney disease
- Liver and lung diseases
- Low levels of calcium, potassium, or magnesium
- Intestinal bleeding or ulceration or blockage
- Allergy to cisapride or any other medications
- Pregnancy (or planning it)
- Breastfeeding
As this medicine causes drowsiness, avoid activities that require full alertness, such as driving and swimming.
https://my.clevelandclinic.org/health/drugs/18304-cisapride-tablets#:~:text=CISAPRIDE%20(SIS%20a%20pride)%20is,other%20medicines%20have%20not%20worked.
https://www.webmd.com/drugs/2/drug-8899/cisapride-oral/details/list-sideeffects
https://medlineplus.gov/druginfo/meds/a694006.html
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REFERENCES:
American College of Gastroenterology. "Acid Reflux." 2017.
<http://patients.gi.org/topics/acid-reflux/>
familydoctor.org. "Heartburn." Updated: Mar 2014.
<https://familydoctor.org/condition/heartburn/>
National Library of Medicine; PubMed Health. "Heartburn and GERD: Treatment options for GERD." Updated: Nov 18, 2015.
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