
Dermatitis herpetiformis (DH) or Duhring’s disease looks similar to herpes lesion (a cluster of dew drops over skin) but is not caused by herpes virus. It is characterized by a cluster of red, itchy, bumpy skin rashes that may affect the elbows, knees, buttocks, lower back, and scalp. The rash can also be confused with eczema or acne.
What is dermatitis herpetiformis?
Dermatitis herpetiformis (DH) is a chronic skin condition caused by gluten sensitivity. Gluten sensitivity means wheat allergy. If we break down the word DH, we get “derm” meaning skin and “itis” meaning inflammation. The blisters look like herpes lesion; hence, the word herpetiformis.
People with DH do not generally exhibit the digestive symptoms commonly seen in patients with celiac disease. 10-25% of people diagnosed with celiac disease have reported DH.
DH is somewhat more common in men than in women, and men are more likely to have unusual oral or genital rashes.
What causes dermatitis herpetiformis?
Who are at risk of dermatitis herpetiformis?
People with the following risk factors are at the highest risk of dermatitis herpetiformis (DH):
- Age between 30 and 40 years
- Male gender
- Family history of DH
- People of European descent
- Relatives having other autoimmune disorders
What are the symptoms of dermatitis herpetiformis?
The first visible sign of dermatitis herpetiformis (DH) is probably a stinging sensation or burning in certain places on your skin. You may also have symptoms in the skin, mouth, and rarely gastrointestinal tract.
Skin symptoms include:
- Extremely itchy bumps or blisters, most often on the elbows, knees, back, and buttocks
- Rashes that are usually the same size and shape on both sides
- The rash may resemble eczema
- Scratch marks and skin erosions instead of blisters in some people
Oral symptoms include:
- Tooth enamel problems
- Pitting (small depression on the surface of the tooth)
- Discoloration of teeth
- Canker sores (ulcer of the mouth)
- Horizontal grooves (cut or fissure on the teeth)
Gastrointestinal symptoms are not so common in DH. However, if there are any symptoms, it may include:
- Bloating
- Cramping
- Diarrhea
- Constipation
- Pain

SLIDESHOW
The 14 Most Common Causes of Fatigue See SlideshowHow is dermatitis herpetiformis treated?
The physician may prescribe the following treatment regimen for dermatitis herpetiformis (DH):
- Medications: This may include:
- Antibiotic: Oral dapsone has proven to get rid of itching and rashes within 1-3 days.
- Topical corticosteroid cream: Applying corticosteroid cream has been beneficial to relieve itching.
- Gluten-free diet: Sticking to a gluten-free diet manages your DH by
- Reducing the necessity for medication to control the skin condition.
- Reducing the risk of other autoimmune diseases.
- Reducing the risk of intestinal tumor.
- Enhancing nutrition and bone density.
The physician may also ask you to avoid iodine to prevent exacerbations of symptoms. It is essential to follow the physician’s advice and treatment for total relief from the disease.
Health Solutions From Our Sponsors
https://my.clevelandclinic.org/health/diseases/21460-dermatitis-herpetiformis/management-and-treatment
Top What Does Dermatitis Herpetiformis Look Like? Related Articles
Atopic Dermatitis
Eczema is a general term for many types dermatitis (skin inflammation). Atopic dermatitis is the most common of the many types of eczema. Other types of eczema include: contact eczema, allergic contact eczema, seborrheic eczema, nummular eczema, stasis dermatitis, and dyshidrotic eczema.Atopic Dermatitis vs Contact Dermatitis
The word dermatitis refers to inflammation (redness and swelling) of the skin. Dermatitis includes various skin conditions that cause irritation or rashes on the skin. It generally causes no serious harm to the body and does not mean that the affected person’s skin is infected or unhygienic.Atopic Dermatitis vs. Eczema
Atopic dermatitis and eczema both refer to skin conditions. Atopic dermatitis is a cause of eczema, which refers to skin conditions that cause inflammation and irritation. The terms are sometimes used interchangeably. Eczema is not a condition in itself, but a description for a group of skin diseases that cause skin inflammation and irritation.betamethasone
Betamethasone is a synthetic steroid taken as an oral medication, injections into the skin, or a topical cream, and is used to treat inflammation from various disorders, including skin conditions, asthma, ulcerative colitis, arthritis, and others. Common side effects include allergic reactions (swelling), acne, hives, itching, irregular heart rhythms (arrhythmia), heart enlargement, fainting, fluid in the lungs (pulmonary edema), blood clot blockage in a blood vessel (thromboembolism), vein inflammation with blood clots (thrombophlebitis), and others. Consult your doctor before taking if pregnant or breastfeeding.Common Medical Abbreviations & Terms
Doctors, pharmacists, and other health-care professionals use abbreviations, acronyms, and other terminology for instructions and information in regard to a patient's health condition, prescription drugs they are to take, or medical procedures that have been ordered. There is no approved this list of common medical abbreviations, acronyms, and terminology used by doctors and other health- care professionals. You can use this list of medical abbreviations and acronyms written by our doctors the next time you can't understand what is on your prescription package, blood test results, or medical procedure orders. Examples include:
- ANED: Alive no evidence of disease. The patient arrived in the ER alive with no evidence of disease.
- ARF: Acute renal (kidney) failure
- cap: Capsule.
- CPAP: Continuous positive airway pressure. A treatment for sleep apnea.
- DJD: Degenerative joint disease. Another term for osteoarthritis.
- DM: Diabetes mellitus. Type 1 and type 2 diabetes
- HA: Headache
- IBD: Inflammatory bowel disease. A name for two disorders of the gastrointestinal (BI) tract, Crohn's disease and ulcerative colitis
- JT: Joint
- N/V: Nausea or vomiting.
- p.o.: By mouth. From the Latin terminology per os.
- q.i.d.: Four times daily. As in taking a medicine four times daily.
- RA: Rheumatoid arthritis
- SOB: Shortness of breath.
- T: Temperature. Temperature is recorded as part of the physical examination. It is one of the "vital signs."
Contact Dermatitis
Contact dermatitis is a rash that occurs after exposure to an irritant. Symptoms of contact dermatitis include a red, elevated rash at the site of contact with the irritating substance. Contact dermatitis treatment may involve creams, application of cool water compresses, and applying topical steroids.dapsone
Dapsone is a medication used to treat leprosy, a chronic infectious disease caused by Mycobacterium leprae, a type of slow-growing bacteria, and dermatitis herpetiformis, an itchy blistering skin condition caused by celiac disease, an autoimmune gastrointestinal inflammatory condition triggered by gluten. Common side effects of dapsone include methemoglobinemia, low red blood cell count, severely low count of granulocyte immune cells (agranulocytosis), increase in immature red cell count (reticulocytosis), abdominal pain, nausea, vomiting, rapid heart rate (tachycardia), male fertility, and others.dexpanthenol
Dexpanthenol is a topical emollient applied on the skin to relieve itching from eczema and other skin disorders, and promote the healing of skin lesions. Common side effects of dexpanthenol include irritation, tingling, itching, hives (urticaria), and allergic reactions. Use with caution if pregnant or breastfeeding. Keep out of reach of children.Eczema and Atopic Dermatitis Rashes Slideshow
Eczema is a common allergic skin condition. Learn more about types of eczema like atopic dermatitis, dyshidrotic eczema and baby eczema. Find treatments like creams for face, hands, scalp, and more.Eczema (Atopic Dermatitis) Quiz:
Does dry, itchy, flaky, scaly, red, inflamed skin sound familiar to you? Take the Eczema (Atopic Dermatitis) Quiz to learn more about the causes, symptoms, and treatments of this common skin condition.fluocinonide
Fluocinonide is a corticosteroid medication topically applied to treat inflammatory skin conditions such as atopic dermatitis, psoriasis, and other skin conditions that respond to corticosteroid treatment. Fluocinonide relieves dryness, redness, itching, scaling, crusting, and other discomforts associated with inflammatory skin conditions. Common side effects of fluocinonide include irritation, itching (pruritus), pain, burning, swelling, redness, discoloration, aggravation of the condition treated, pimples/zits (acne vulgaris), allergic dermatitis, contact dermatitis, dermatitis around the mouth (perioral dermatitis), thinning of the skin (atrophy), stretch marks (striae), inflammation of follicles (folliculitis), excessive hair growth (hypertrichosis), and others.How Do You Treat Perioral Dermatitis?
Perioral dermatitis (POD) is a rash that involves the skin around the mouth. The rash of POD is bumpy and scaly in appearance. There may be itching and pain, along with the discharge of clear fluid from the rash.hydrocortisone
Hydrocortisone is used as an oral medication, injection, and topical cream to treat allergic skin conditions, such as atopic dermatitis, corticosteroid dermatoses (skin lesions), and inflammation. Side effects of hydrocortisone include allergic reactions, cardiac arrest, irregular heart rhythms (arrhythmia), pulmonary edema, fainting (syncope), blood clot blockage in a blood vessel (thromboembolism), and others. Severe interactions of hydrocortisone include mifepristone. Consult your doctor before taking if pregnant or breastfeeding.hydroquinone
Hydroquinone is a depigmenting agent used to treat dyschromia, a condition of skin discoloration or patches of uneven skin color, caused by freckles, melasma, sun spots/liver spots, and hyperpigmentation. The effects of hydroquinone are reversed with its discontinuation and sun exposure. Common side effects of hydroquinone include mild skin irritation, burning and stinging, allergic contact dermatitis, redness (erythema), dryness of skin, and inflammation. Use with caution in pregnant and lactating women.propolis
Propolis is a natural adhesive and resin-like substance produced and used by bees that is commercially available in the form of capsules, mouthwash solutions, throat lozenges, powder and topical formulations such as ointments, creams, and lotions. Propolis has many uses, which include common cold and respiratory infections, inflammatory gastrointestinal conditions such as colitis and diverticulitis, cancer, herpes simplex infections, improvement of insulin sensitivity and glycemic control in type 2 diabetes, reducing alcohol-induced liver injury, treatment of wounds, burns, acne, psoriasis, and dermatitis; and others.Seborrheic Dermatitis
Seborrheic dermatitis is a chronic skin condition. Symptoms and signs include a red, scaling rash on the scalp, face, ears, and torso. Treatment often includes the use of a medicated shampoo and the application of a topical steroid lotion.Skin Problems and Treatments: Guide to Seborrheic Dermatitis
Get to know the symptoms and treatments of seborrheic dermatitis, a common skin condition that often affects the scalp but can happen in other areas, too.urea
Urea is an emollient used in the treatment of many skin disorders that cause dry, rough, thick, and scaly skin, including dermatitis, eczema, psoriasis, keratosis pilaris, corns, calluses, ingrown nails, and more. Common side effects of urea include local irritation, transient stinging of the skin, transient burning sensation, itching (pruritus), redness, and rash. Applying too much urea products on the skin can cause irritation, redness, itching and pain.