What Are the Odds of Getting Cancer?

Medically Reviewed on 6/8/2022

Lifetime risk of getting cancer

The term cancer refers to uncontrolled growth of cells in the body. There are trillions of cells in our body. Under normal circumstances, the cells grow and divide according to the body's needs.
Cancer can affect almost any part of the body from the head to the toes and is named according to the site of origin.

The term cancer refers to the uncontrolled growth of cells in the body. There are trillions of cells in our body. Under normal circumstances, the cells grow and divide according to the body’s needs. When the cells become old or develop any abnormality, they die. Thus, the growth, division, and death of the cells occur under regulated conditions in the body. This ensures that body functions occur optimally while maintaining the structure of various tissues and organs in the body. When this regulation of cell growth, division, and death is disturbed, cancer begins. Thus, the abnormal or “cancerous” cell is no more under the control of the regulatory machinery, and it keeps dividing to produce more cells of its type. This leads to the crowding of cells at the affected site. The abnormal cells devour the nutrients and oxygen while depriving the normal cells of nutrients, oxygen, and even space. The abnormal cells invade nearby and distant sites (metastasis) hampering normal functioning wherever they go.

Cancer can affect almost any part of the body from the head to the toes and is named according to the site of origin. Cancer can be divided into two broad categories.

  1. Hematologic or blood cancer: It arises from any of the blood cells. Examples include lymphoma, leukemia, and multiple myeloma.
  2. Solid tumor cancer: It arises from the tissues and organs other than the blood cells. Examples include breast, prostate, lung, colorectal and ovarian cancer.

One in three people in the United States suffers from cancer. Cancer is the second leading cause of death worldwide. It affects around 1.8 million people each year in the United States. Moreover, it causes the second-highest number of deaths (after ischemic heart disease) in the United States. It was responsible for around 606,520 deaths in 2020.

The odds of having any type of cancer depend on the presence of several risk factors that make you more likely to have that cancer. These include factors such as

  • Age
  • Gender
  • Personal or family history of cancer
  • Exposure to any cancer-causing chemicals or ultraviolet (UV) rays
  • A lifestyle that includes addictions (smoking and alcohol consumption)

Thus, the lifetime risk or odds of developing or dying from any type of cancer differ from person to person.

Lifetime risk of developing or dying from cancer

The risk of cancer or dying from it can be expressed in two ways: percentage and odds. Thus, if a man’s risk of dying from breast cancer in the United States is 0.03 percent, it means he has around 1 in 3,333 (100/0.03) chance of dying from breast cancer. In terms of odds, it means around 1 in 3,333 men in the United States will die from breast cancer.

The lifetime risks of developing and dying from certain cancers for men and women in the United States are given in the tables below. Data are taken from the National Cancer Institute’s Surveillance Epidemiology and End Results (SEER) database. Risks are expressed as an average for the entire US population. Thus, your individual risk may vary depending upon the presence or absence of any risk factors.

Males

Table 1. Risk of developing or dying from cancer for men in the United States
Risk of developing Risk of dying from

% 1 in % 1 in
All invasive sites 40.2 2 20.5 5
Bladder (includes in situ) 3.8 26 0.9

109

Brain and nervous system 0.7 143 0.5 188
Breast 0.1 727 <0.1 3,260
Colon and rectum 4.2 24 1.8 57
Esophagus 0.8 126 0.7 137
Hodgkin lymphoma 0.2 434 <0.1 2,792
Kidney and renal pelvis 2.2 46 0.6 175
Larynx (voice box) 0.5 200 0.2 561
Leukemia 1.9 54 0.9 107
Liver and bile duct 1.5 69 1 97
Lung and bronchus 6.4 16 5 20
Melanoma of the skin 3.7 27 0.4 235
Multiple myeloma 1.0 105 0.5 218
Non-Hodgkin lymphoma 2.4 42 0.8 126
Oral cavity and pharynx 1.7 60 0.4 239
Pancreas 1.7 59 1.4 71
Prostate 12.5 8 2.4 41
Stomach 1.0 98 0.4 239
Testicles 0.4 244 <0.1 4,982
Thyroid 0.7 149 0.1 1,699

Females

Table 2. Risk of developing or dying from cancer for females in the United States
Risk of developing Risk of dying from

% 1 in % 1 in
All invasive sites 38.5 3 17.9 6
Bladder (includes in situ) 1.2 86 0.3 292
Brain and nervous system 0.5 186 0.4 239
Breast 12.9 8 2.5 39
Cervix 0.6 159 0.2 461
Colon and rectum 4.0 25 1.6 62
Esophagus 0.2 433 0.2 513
Hodgkin lymphoma 0.2 517 0 3.683
Kidney and renal pelvis 1.3 79 0.3 311
Larynx (voice box) 0.1 835 0 2,239
Leukemia 1.3 77 0.7 150
Liver and bile duct 0.6 157 0.5 182
Lung and bronchus 6.0 17 4.2 24
Melanoma of the skin 2.5 40 02 463
Multiple myeloma 0.7 138 04 272
Non-Hodgkin lymphoma 1.9 52 0.6 164
Oral cavity and pharynx 0.7 140 0.2 536
Pancreas 1.6 61 1.4 73
Ovary 1.2 85 0.8 119
Stomach 0.7 152 0.3 351
Testicles 0.4 244 <0.1 4,982
Thyroid 1.8 55 0.1 1,413
Uterus 3.1 32 0.7 154

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Medically Reviewed on 6/8/2022
References
https://www.cancer.org/cancer/cancer-basics/lifetime-probability-of-developing-or-dying-from-cancer.html