An autoimmune disorder occurs when a person’s immune system mistakenly attacks their own body tissues such as the skin or joints considering them as foreign. Below are a few common autoimmune disorders:
- Addison’s disease: In Addison’s disease, patients have deficiency in the production of glucocorticoid hormones due to severe and insufficient functioning of the outer layer of the adrenal gland. This disease is relatively uncommon.
- Adult Still’s disease: It is a type of swelling arthritis that features fevers, rash, and joint pain.
- Agammaglobulinemia: It is related to hypogammaglobulinemia (antibody deficiency) and is manifested in a variety of immune deficiency disorders in which the immune system is compromised.
- Alopecia areata: It is a disorder which is characterized by patchy hair loss.
- Amyloidosis: It is a disorder in which abnormal proteins build up in tissues and organs.
- Ankylosing spondylitis: It is an arthritis of the spine where the spine loses its normal elasticity.
- Anti–glomerular basement membrane/Anti–tubular basement membrane nephritis: It is a disorder caused by autoantibodies that attack the walls of capillaries (small blood vessels) in the kidney.
- Antiphospholipid syndrome: It is also called as Hughes syndrome or sticky blood. It results in multiple miscarriages.
- Autoimmune hepatitis: It is a severe inflammatory autoimmune disease of the liver.
- Autoimmune inner ear disease: There is a progressive non–age-related sensorineural hearing loss.
- Autoimmune oophoritis: There is an autoimmune swelling of ovaries resulting in destruction, atrophy, and fibrosis with a loss of fertility and ovary hormonal production.
- Autoimmune orchitis: It is characterized by testis swelling and the presence of specific antisperm antibodies.
- Axonal and neuronal neuropathy: It is characterized by the loss of muscle function with absence of neurologic reflexes such as the knee jerk reaction, often causing respiratory failure.
- Behcet’s disease: Severe multisystem autoimmune disease involving swelling of blood vessels, called vasculitis, throughout the body. It causes sores in mouth and other parts.
- Benign mucosal pemphigoid: It is a severe autoimmune disease characterized by erosive skin lesions of the mucous membranes.
- Castleman disease: It is a disease of lymph nodes and related tissues. There’s an abnormal overgrowth of cells of the lymph system that is similar in many ways to lymphomas (cancers of lymph nodes).
- Celiac disease: People with this disease can’t eat gluten because immune system may damage their small intestine.
- Chronic inflammatory demyelinating polyneuropathy: This is an autoimmune disorder in which there is swelling of nerve roots and destruction of the myelin sheath (covering) over the nerves. This causes weakness, paralysis, and/or impairment in motor function, especially of the arms and legs. Sensory loss may also be present.
- Churg-Strauss syndrome: It is characterized by accumulated antibodies, swelling of blood vessels, and abnormal clustering of white blood cells. An allergic reaction or asthma may precede the syndrome’s development by several years.
- Cogan’s syndrome: There’s swelling of the eye with hearing problems and dizziness.
- Cold agglutinin disease: It is characterized by anemia caused by cold-reacting autoantibodies (a type of protein produced by the immune system).
- Crohn’s disease: It is an autoimmune bowel disease characterized by severe and persistent swelling of the lining or wall of the gastrointestinal tract.
- Dermatomyositis: It is an autoimmune muscle disease that involves swelling and skin rash.
- Devic’s disease: It is a condition that affects the spinal cord and the optic nerve (nerves that carry information regarding sight from the eye).
- Dressler’s syndrome: It is a condition which causes swelling of the pericardium (sac surrounding the heart).
- Evans syndrome: Immune system destroys the body’s red blood cells, white blood cells, and/or platelets.
- Granulomatosis with Polyangiitis or Wegener’s Granulomatosis: Swelling of blood vessels and other tissues are noted. This swelling limits blood flow to important organs in the body, potentially leading to long-term damage.
- Graves’ disease: It is an autoimmune thyroid disease that causes the thyroid gland to produce excessive hormones. Symptoms may include nervousness, weight loss, heart palpitations, and intolerance to heat.
- Guillain-Barre syndrome: It is a disorder that causes immune system to attack own peripheral nervous system, which nerves connect brain and spinal cord with the rest of your body.
- Hashimoto’s thyroiditis: Immune system attacks and destroys the thyroid gland.
- Hemolytic anemia: It causes the premature destruction of red blood cells.
- Immune thrombocytopenic purpura and thrombocytopenic purpura: It is a bleeding disorder. The immune system destroys platelets that are necessary for normal blood clotting.
- Juvenile myositis , including juvenile dermatomyositis and juvenile polymyositis: This is a group of life-threatening autoimmune diseases, in which the body’s immune system attacks its own cells and tissues.
- Lambert-Eaton syndrome: It is an autoimmune disorder in which faulty communication between nerves and muscles leads to muscle weakness.
- Multiple sclerosis: It is a nervous system disease that affects your brain and spinal cord.
- Myasthenia gravis: It is an autoimmune disease that causes weakness in the muscles; this happens because of a problem in communication between nerves and muscles.
- Palindromic rheumatism: It is characterized by sudden, multiple, and recurring attacks of joint pain and swelling, typically in the hands and feet.
- Pemphigus: It is a group of severe autoimmune skin diseases characterized by blister formations in the outer layer of the skin and the mucous membranes.
- POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes): It is an autoimmune-related blood disorder that damages your nerves and affects many other parts of the body.
- Polyarteritis nodosa: It is a serious autoimmune-related blood vessel disease.
- Psoriasis: It is an autoimmune skin disease that causes itchy or sore patches of thick, red skin with silvery scales. Some people with psoriasis have psoriatic arthritis. It causes pain, stiffness, and swelling of the joints.
- Retroperitoneal fibrosis: It is a disorder that blocks the tubes that carry urine from the kidneys to the bladder.
- Rheumatoid arthritis: It causes pain, swelling, stiffness, and loss of function in joints.
- Sarcoidosis: It is an autoimmune disease that leads to swelling in lungs, skin, or lymph nodes.
- Schmidt syndrome: It is an autoimmune syndrome that commonly has the constellation of three diseases, namely, diabetes mellitus type 1, hypothyroidism, and adrenal insufficiency.
- Scleroderma or hard skin: There’s an abnormal growth of connective tissue.
- Sjögren’s syndrome: It causes dryness in your mouth, eyes, nose, throat, and skin.
- Systemic Lupus Erythematosus: It is an autoimmune disorder which affects multiple body systems, primarily kidneys and joints.
- Susac’s syndrome: Patients display personality changes, bizarre and paranoid behavior, impaired speech, confusion, headaches, and hearing problem.
- Takayasu’s arteritis: It affects the aorta (the largest blood vessel in the body) and its branches.
- Thyroid eye disease: Body mistakenly attacks the cells around the eyes.
- Tolosa-Hunt syndrome: It is characterized by severe and unilateral headaches with pain around the sides and back of the eye, along with weakness and paralysis of certain eye muscles.
- Type 1 diabetes: In type 1 diabetes, pancreas does not make insulin.
- Ulcerative colitis: It causes ulcers, in the lining of the rectum and end part of intestine.
- Undifferentiated connective tissue disease (UCTD): It is systemic autoimmune disease. In UCTD, autoimmunity may cause the immune system to attack specific parts of the body resulting in a variety of problems.
Health Solutions From Our Sponsors
Top What Are the Different Autoimmune Disorders? Related Articles
ambenoniumAmbenonium is a discontinued prescription drug used to treat myasthenia gravis, an autoimmune neuromuscular disease. Ambenonium should be used with caution in people with asthma, Parkinson’s disease, and mechanical intestinal or urinary obstruction. Common side effects of ambenonium include nausea, vomiting, abdominal cramps, diarrhea, excessive salivation, increase in bronchial secretions, excessive watering of eyes (lachrymation), sweating, excessive urination (pollakiuria), urinary urgency, muscle twitches (fasciculation), paralyzed tongue muscles, paralyzed respiratory muscles, difficulty swallowing, difficulty breathing, shortness of breath (dyspnea), and others.
Arcalyst (rilonacept)Arcalyst is a prescription medicine called an interleukin-1 (IL-1) blocker used to treat adults and children with Cryopyrin-Associated Periodic Syndromes (CAPS), including Familial Cold Auto-inflammatory Syndrome (FCAS) and Muckle Wells Syndrome (MWS). Serious side effects of Arcalyst include Changes in your blood cholesterol and triglycerides (lipids) and allergic reaction.
Can a Weak Immune System Cause Cancer?Your immune system plays a vital role in maintaining your health. Although some cancers are caused by genetic mutations, some other factors like old age and a weakened immune system can also play a significant role in causing the disease.
Can You Live a Long Life With Autoimmune Disease?You may be concerned that your condition will affect your projected lifespan. Most people can expect to live a long life with an autoimmune disease, though.
Common Medical Abbreviations & Terms
Doctors, pharmacists, and other health-care professionals use abbreviations, acronyms, and other terminology for instructions and information in regard to a patient's health condition, prescription drugs they are to take, or medical procedures that have been ordered. There is no approved this list of common medical abbreviations, acronyms, and terminology used by doctors and other health- care professionals. You can use this list of medical abbreviations and acronyms written by our doctors the next time you can't understand what is on your prescription package, blood test results, or medical procedure orders. Examples include:
- ANED: Alive no evidence of disease. The patient arrived in the ER alive with no evidence of disease.
- ARF: Acute renal (kidney) failure
- cap: Capsule.
- CPAP: Continuous positive airway pressure. A treatment for sleep apnea.
- DJD: Degenerative joint disease. Another term for osteoarthritis.
- DM: Diabetes mellitus. Type 1 and type 2 diabetes
- HA: Headache
- IBD: Inflammatory bowel disease. A name for two disorders of the gastrointestinal (BI) tract, Crohn's disease and ulcerative colitis
- JT: Joint
- N/V: Nausea or vomiting.
- p.o.: By mouth. From the Latin terminology per os.
- q.i.d.: Four times daily. As in taking a medicine four times daily.
- RA: Rheumatoid arthritis
- SOB: Shortness of breath.
- T: Temperature. Temperature is recorded as part of the physical examination. It is one of the "vital signs."
efgartigimod alfa-fcab (Vyvgart)Vyvgart efgartigimod alfa-fcab injection is a prescription medicine used to treat the symptoms of the autoimmune neuromuscular disease Myasthenia gravis (gMG) in adults who test positive for the antiacetylcholine receptor (AChR) antibody. Serious side effects of Vyvgart include hives, difficulty breathing, swelling of your face/lips/tongue/throat, severe dizziness, fever, and sore throat.
Firdapse (amifampridine)Firdapse is a prescription medicine used to treat Lambert-Eaton myasthenic syndrome (LEMS), an autoimmune disease, in adults. It is not known if Firdapse is safe or effective in children. Serious side effects of Firdapse include seizures and serious allergic reactions (anaphylaxis).
glandular productsGlandular products are nutritional supplements used to enhance the function or mimic the effect of an organ. Glandular products can be used to treat hypothyroidism, low adrenal function, autoimmune disorders, adrenocortical insufficiency, hyperkalemia, ulcerative colitis, liver disorders, vascular insufficiencies, pancreatic disorders, and others. Common side effects of glandular products include allergic reactions, hyperthyroidism symptoms, iron overload, infection, and others.
How Are Antibodies Produced and What's Their Role in the Immune System?Antibodies are created when your immune system reacts to toxins, pollen, and infectious organisms. Your body is constantly making antibodies. There are different kinds of antibodies, but all are necessary to the immune system to fight foreign bacteria and viruses.
16 Immune Boosting FoodsHelp fight colds, flu, as well as viruses like coronavirus with foods that boost and improve your immune system. Reach for bright-colored antioxidant and vitamin-rich fruits and vegetables such berries, broccoli, garlic, ginger, tea and more for vibrant health.
How Your Immune System FunctionsWhat is the immune system and its function? Your immune system finds and kills germ invaders when you are sick from a cold, the flu, or other diseases like COVID-19. Learn every part of your complex immune system, and what diseases come from an overactive or weak immune system.
What Is Microsporidiosis?Microsporidiosis is an infection caused by the microsporidia parasite. The disease is uncommon in people with normal immune systems. Symptoms in people with immune deficiency include diarrhea, malabsorption, gallbladder disease, cough, labored breathing, urinary tract infection, bowel perforation and keratoconjunctivitis. Microsporidiosis treatment depends on the site of infection and the species of microsporidia involved.
Prostate Cancer Treatment: Chemotherapy, Bone-Targeted and Immune Therapy
Doctors may introduce chemotherapy and immune therapy if other measures fail to cure a case of prostate cancer. However, unlike with other forms of cancer, chemotherapy isn’t the first choice for early prostate cancer. Immune therapy uses the body's own immune system to attack the prostate tumor, while bone-targeted therapy aims to preserve bone and prevent metastasis.
Top 15 Immune System BoostersImmune system boosters include foods, supplements, and lifestyle habits to help you fight off infections. A healthy immune system benefits your body and boosts your defenses against viruses (coronavirus), bacteria, and other pathogens.
Cold, Flu, and Cough: Things That Suppress Your Immune SystemA strong immune system is your best protection against infections and illnesses. Find out what can weaken that defense.
What Are the Symptoms of Myopathy?The most common symptoms of myopathy are weakness and impaired daily functions or activities, as well as muscle pain and tenderness. General signs and symptoms of myopathy include symmetric proximal muscle weakness, fatigue and malaise, motor delay, bulbar muscle dystrophy (dysfunction of the swallowing and speech muscles), myoglobinuria (dark-colored urine) and/or fever, no paresthesia (sensory impairments), atrophy and hyporeflexia, consciousness at normal levels, and Gottron papules (dermatomyositis) over the knuckles, elbows, and knees.
What Diseases Can Cause a Positive ANA?An antinuclear antibody (ANA) test shows signs of autoimmune disease. Diseases that may cause a positive ANA include scleroderma, rheumatoid arthritis, thyroid disease, and other conditions.
What Foods Are Good and Bad for Sjogren’s Syndrome?What is Sjogren’s Syndrome? Learn more about this autoimmune disorder, what causes it, good and bad foods, and how it is treated.