- Take the Kidney Disease Quiz
- Kidney Stones Slideshow Pictures
- High Blood Pressure Slideshow Pictures
What is Veltassa (patiromer), and what is it used for?
Veltassa is indicated for the treatment of hyperkalemia, or high levels of potassium. High levels of potassium usually are caused by kidney or adrenal gland malfunctions and may cause
Veltassa works in the colon by binding with potassium from your food and preventing your body from absorbing it.
- Veltassa should not be used as an emergency treatment for life-threatening hyperkalemia because of its delayed onset of action
- Veltassa is contraindicated in patients with a history of a hypersensitivity reaction to Veltassa or any of its components
- Because Veltassa is not absorbed into the bloodstream, doctors consider it low-risk for pregnant women and nursing mothers.
What are the side effects of Veltassa (patiromer)?
Worsening of Gastrointestinal Motility
Avoid use of Veltassa in patients with severe constipation, bowel obstruction or impaction, including abnormal post-operative bowel motility disorders, because Veltassa may be ineffective and may worsen gastrointestinal conditions.
Patients with a history of bowel obstruction or major gastrointestinal surgery, severe gastrointestinal disorders, or swallowing disorders were not included in the clinical studies.
Veltassa binds to magnesium in the colon, which can lead to hypomagnesemia. In clinical studies, hypomagnesemia was reported as an adverse reaction in 5.3% of patients treated with Veltassa. Monitor serum magnesium.
Consider magnesium supplementation in patients who develop low serum magnesium levels on Veltassa.
During the clinical studies, the most commonly reported adverse reactions leading to discontinuation of Veltassa were gastrointestinal adverse reactions (2.7%), including
What is the dosage for Veltassa (patiromer)?
Administer Veltassa at least 3 hours before or 3 hours after other oral medications
Do not heat Veltassa (e.g., microwave) or add to heated foods or liquids. Do not take Veltassa in its dry form.
- Measure 1/3 cup of water.
- Pour half of the water into a glass, then add Veltassa and stir.
- Add the remaining half of the water and stir thoroughly.
- The powder will not dissolve and the mixture will look cloudy.
- Add more water to the mixture as needed for desired consistency.
- Drink the mixture immediately.
- If powder remains in the glass after drinking, add more water, stir and drink immediately. Repeat as needed to ensure the entire dose is administered.
The recommended starting dose of Veltassa is 8.4 grams patiromer once daily. Monitor serum potassium and adjust the dose of Veltassa based on the serum potassium level and the desired target range.
The dose may be increased or decreased, as necessary, to reach the desired serum potassium concentration, up to a maximum dose of 25.2 grams once daily. The dose can be up-titrated based on serum potassium level at 1-week or longer intervals, in increments of 8.4 grams.
What drugs interact with Veltassa (patiromer)?
In clinical studies, Veltassa decreased systemic exposure of some coadministered oral medications. Binding of Veltassa to other oral medications could cause decreased gastrointestinal absorption and loss of efficacy when taken close to the time Veltassa is administered.
Administer other oral medications at least 3 hours before or 3 hours after Veltassa.
Is Veltassa (patiromer) safe to take while pregnant or breastfeeding?
Veltassa is not absorbed systemically following oral administration and maternal use is not expected to result in fetal risk. Veltassa is not absorbed systemically by the mother, so breastfeeding is not expected to result in risk to the infant.
Latest Medications News
Daily Health News
Veltassa is indicated for the treatment of hyperkalemia, or high levels of potassium. High levels of potassium usually are caused by kidney or adrenal gland malfunctions and may cause nausea, fatigue, weakness, and slow heartbeat. Veltassa works in the colon by binding with potassium from your food and preventing your body from absorbing it.
Multimedia: Slideshows, Images & Quizzes
Kidney Stones: Symptoms, Causes, and Treatment
What causes kidney stones? Where is kidney stone pain located on your body? Learn the symptoms and signs of kidney stone pain....
Kidney Disease Quiz: Test Your Medical IQ
Kidney disease is common. Take this kidney disease quiz to test your knowledge and learn the symptoms, causes and types of kidney...
Picture of Kidney Stone Crystal
Kidney stones are made of salts and minerals in the urine that stick together, creating small "pebbles" formed within the kidney...
Picture of Kidney Stone Diagnosis
The diagnosis of kidney stones is suspected by the typical pattern of symptoms when other possible causes of the abdominal or...
Picture of Kidney Stone
A stone in the kidney (or lower down in the urinary tract). See a picture of Kidney Stone and learn more about the health topic.
Picture of Kidneys
The kidneys are a pair of organs located in the back of the abdomen. See a picture of the Kidneys and learn more about the health...
Related Disease Conditions
Kidney (Renal) Failure
Kidney failure can occur from an acute event or a chronic condition or disease. Prerenal kidney failure is caused by blood loss, dehydration, or medication. Some of the renal causes of kidney failure include sepsis, medications, rhabdomyolysis, multiple myeloma, and acute glomerulonephritis. Post renal causes of kidney failure include bladder obstruction, prostate problems, tumors, or kidney stones.Treatment options included diet, medications, or dialysis.
The First Signs of Kidney Stones (Nephrolithiasis)
Kidney stones are solid masses of crystalline material that form in the kidneys. Symptoms of kidney stones can include pain, nausea, vomiting, and even fever and chills. Kidney stones are diagnosed via CT scans and specialized X-rays. Treatment of kidney stones involves drinking lots of fluids and taking over-the-counter pain medications to medical intervention including prescription medications, lithotripsy, and sometimes even surgery.
Kidney Pain: Symptoms, Treatment, and Causes
Kidney pain has a variety of causes and symptoms. Infection, injury, trauma, bleeding disorders, kidney stones, and less common conditions may lead to kidney pain. Symptoms associated with kidney pain may include fever, vomiting, nausea, flank pain, and painful urination. Treatment of kidney pain depends on the cause of the pain.
Kidney Infection (Pyelonephritis)
Kidney infection (pyelonephritis) usually is caused by E. coli and other bacteria that have spread from the bladder from a UTI (urinary tract infection), poor hygiene, sexual intercourse, pregnancy, catheter, cystoscope exam, surgery, kidney stones, or prostate enlargement. Symptoms of kidney infection include back pain, frequent urination, pain during urination, fever, and or pus or blood in the urine. Kidney infection can be cured with antibiotic treatment. Cranberry juice may prevent UTIs, but that hasn’t been proven in all research studies.
Kidney Pain vs. Back Pain
The signs and symptoms of kidney pain and back pain depend upon the underlying cause. Doctors may use blood tests, X-rays, CT, and/or MRI to diagnose kidney pain and back pain. Treatment may include rest, ice, stretching, muscle strengthening, and pain-relieving medications.
Kidney Infection in Adults
Second Source article from Government
Kidney Stones in Adults
Second Source article from Government
Second Source article from Government
Hypertension-Related Kidney Disease
Second Source WebMD Medical Reference
Hypertensive Kidney Disease
High blood pressure can damage the kidneys and is one of the leading causes of kidney failure (end-stage renal kidney disease). Kidney damage, like hypertension, can be unnoticeable and detected only through medical tests. If you have kidney disease, you should control your blood pressure. Other treatment options include prescription medications.
There are several types of kidney cancer, including renal cell cancer (renal adenocarcinoma or hypernephroma), transitional cell carcinoma, and Wilms tumor. Symptoms of kidney cancer include blood in the urine, an abdominal lump or mass, chronic pain in the side, and tiredness. Treatment of kidney cancer -- which may include surgery, arterial embolization, radiation therapy, biological therapy or chemotherapy -- depends upon the stage of the disease and the patient's overall health.
Diabetes and Kidney Disease
In the United States diabetes is the most common cause of kidney failure. High blood pressure and high levels of blood glucose increase the risk that a person with diabetes will eventually progress to kidney failure. Kidney disease in people with diabetes develops over the course of many years. albumin and eGFR are two key markers for kidney disease in people with diabetes. Controlling high blood pressure, blood pressure medications, a moderate protein diet, and compliant management of blood glucose can slow the progression of kidney disease. For those patients who's kidneys eventually fail, dialysis or kidney transplantation is the only option.
Kidney Dysplasia: In Infants and Children
Kidney dysplasia is a condition in which one or both of a baby's kidneys do not develop normally. In kidney dysplasia, cysts replace normal kidney tissue. Signs of kidney dysplasia include enlarged kidneys and, rarely, high blood pressure. A child with kidney dysplasia may not have any symptoms. Genes and maternal exposure to certain drugs may cause kidney dysplasia. Regular checkups should include blood pressure measurements, kidney function tests, and urine testing for protein.
Treatment & Diagnosis
- Kidney Disease FAQs
- Kidney Infections During Pregnancy
- Polycystic Kidney Disease Gene Isolated
- Kidney Stones and Calcium
- What Are Risk Factors for Diabetic Kidney Disease?
- Does Kidney Transplant or Chronic Dialysis Offer Longer Survival?
- Side Effects of Zyloprim (Allopurinol) for Kidney Damage Prevention
- How Are Kidney Stones Diagnosed?
- Kidney Stone Causes
- Lacerated Kidney Symptoms, Treatment, and Recovery Time
- What Are the Symptoms and Signs of Kidney Stones?
- Kidney Stone Treatment
- Kidney Stones: Symptoms and Prevention Podcast
- Blood Pressure Elevation Established as Risk for Kidney Failure
Medications & Supplements
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.