- Side Effects
- Drug Interactions
- Pregnancy & Breastfeeding
- What Else to Know
Generic Name: valsartan
Brand Name: Diovan
Drug Class: ARBs
What is valsartan, and what is it used for?
Valsartan is an oral medication that is used to treat high blood pressure and congestive heart failure. It also is prescribed after heart attacks since valsartan may reduce deaths in patients who developed congestive heart failure after a heart attack. Valsartan also may reduce hospitalizations in patients with congestive heart failure.
Angiotensin, formed in the blood by the action of angiotensin-converting enzyme (ACE), is a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on smooth muscle cells of blood vessels. Angiotensin's attachment to the receptors causes the blood vessels to narrow (vasoconstrict) which leads to an increase in blood pressure (hypertension). Valsartan blocks the angiotensin receptor. By blocking the action of angiotensin, valsartan dilates blood vessels and reduces blood pressure.
Valsartan was approved by the FDA in December 1996.
What are the side effects of valsartan?
Valsartan is generally well-tolerated. The most common side effects are:
Other important side effects are:
What is the dosage for valsartan?
- The usual dose of valsartan for adults with high blood pressure is 80 to 160 mg once daily.
- The maximum dose is 320 mg daily. Maximum blood pressure reduction occurs within 4 weeks.
- For congestive heart failure, the usual dose is 40 mg twice daily.
- The doses may be increased to 80-160 mg twice daily.
- The initial dose after a heart attack is 20 mg twice daily.
- The dose may be increased to 160 mg twice daily if tolerated without side effects.
Which drugs interact with valsartan?
- Combining valsartan with potassium-sparing diuretics (for example., spironolactone (Aldactone), triamterene, amiloride), potassium supplements, or salt substitutes containing potassium may lead to hyperkalemia (elevated potassium in the blood) and in heart failure patients, it increases serum creatinine, a blood test used for monitoring function of the kidneys.
- Combining valsartan or other ARBs with nonsteroidal anti-inflammatory drugs (NSAIDs) in patients who are elderly, fluid-depleted (including those on diuretic therapy), or with poor kidney function may result in reduced kidney function, including kidney failure. These effects are usually reversible. There have been reports that aspirin and other NSAIDs such as ibuprofen (Advil, Children's Advil/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever, etc.), indomethacin (Indocin, Indocin-SR), and naproxen (Anaprox, Naprelan, Naprosyn, Aleve) may reduce the effects of ARBs.
Pregnancy and breastfeeding
- When used in the second or third trimester of pregnancy, valsartan and similar drugs can cause injury and even death to the fetus. Valsartan should not be used during pregnancy. When pregnancy is detected, valsartan should be stopped as soon as possible.
- It is not known whether valsartan is secreted into human milk. Valsartan is secreted into the milk of rats.
What else should I know about valsartan?
Preparations, storage, generic and prescription information about valsartan
- Valsartan is available as Tablets: 40, 80, 160 and 320 mg. Tablets are scored and can be split.
- Capsules should be stored at room temperature, 15-30 C (59-86 F).
- Valsartan is available in generic form. You need a prescription for Vasartan.
Valsartan is an ARB drug prescribed for the treatment of high blood pressure and congestive heart failure. Valsartan is generally well-tolerated. The most common side effects are headache, dizziness, fatigue, abdominal pain, cough, diarrhea, and nausea. Do not take valsartan during pregnancy because of the risk of fetal harm. Consult your doctor before taking if breastfeeding.
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Related Disease Conditions
High Blood Pressure (Hypertension)
High blood pressure (hypertension) is a disease in which pressure within the arteries of the body is elevated. About 75 million people in the US have hypertension (1 in 3 adults), and only half of them are able to manage it. Many people do not know that they have high blood pressure because it often has no has no warning signs or symptoms. Systolic and diastolic are the two readings in which blood pressure is measured. The American College of Cardiology released new guidelines for high blood pressure in 2017. The guidelines now state that blood normal blood pressure is 120/80 mmHg. If either one of those numbers is higher, you have high blood pressure. The American Academy of Cardiology defines high blood pressure slightly differently. The AAC considers 130/80 mm Hg. or greater (either number) stage 1 hypertension. Stage 2 hypertension is considered 140/90 mm Hg. or greater. If you have high blood pressure you are at risk of developing life threatening diseases like stroke and heart attack.REFERENCE: CDC. High Blood Pressure. Updated: Nov 13, 2017.
What Is Considered Stroke-Level High Blood Pressure?
Blood pressure readings above 180/120 mmHg are considered stroke-level and require immediate medical attention. Check out the center below for more medical references on hypertension, including multimedia (slideshows, images, and quizzes), related diseases, treatment, diagnosis, medications, and prevention or wellness.
Congestive Heart Failure (CHF)
Congestive heart failure (CHF) refers to a condition in which the heart loses the ability to function properly. Heart disease, high blood pressure, diabetes, myocarditis, and cardiomyopathies are just a few potential causes of congestive heart failure. Signs and symptoms of congestive heart failure may include fatigue, breathlessness, palpitations, angina, and edema. Physical examination, patient history, blood tests, and imaging tests are used to diagnose congestive heart failure. Treatment of heart failure consists of lifestyle modification and taking medications to decrease fluid in the body and ease the strain on the heart. The prognosis of a patient with congestive heart failure depends on the stage of the heart failure and the overall condition of the individual.
Chronic cough is a cough that does not go away and is generally a symptom of another disorder such as asthma, allergic rhinitis, sinus infection, cigarette smoking, GERD, postnasal drip, bronchitis, pneumonia, medications, and less frequently tumors or other lung disease. Chronic cough treatment is based on the cause, but may be soothed natural and home remedies.
Is Turmeric OK to Take With High Blood Pressure?
Turmeric is an ancient remedy, a perennial plant in the ginger family. Turmeric may help lower blood pressure, but talk to your doctor if you take medication to make sure it doesn't interact with it.
Things to Know About High Blood Pressure Treatment
High blood pressure (hypertension) means high pressure (tension) in the arteries. Treatment for high blood pressure include lifestyle modifications (alcohol, smoking, coffee, salt, diet, exercise), drugs and medications such as ACE inhibitors, angiotensin receptor blockers, beta blockers, diuretics, calcium channel blockers (CCBs), alpha blockers, clonidine, minoxidil, and Exforge.
What Are the 4 Stages of Congestive Heart Failure?
The New York Heart Association developed the four stages of congestive heart failure depending on the functional capabilities of the heart which includes Class I, Class II, Class III, and Class IV.
Can High Blood Pressure (HBP) Cause Blood in Urine?
Blood in your urine is also known as hematuria. Very rarely, it is caused by high blood pressure (HBP) — also known as hypertension.
Febrile seizures, or convulsions caused by fever, can be frightening in small children or infants. However, in general, febrile seizures are harmless. Febrile seizure is not epilepsy. It is estimated that one in every 25 children will have at least one febrile seizure. It is important to know what to do to help your child if he/she has a febrile seizure. Some of the features of a febrile seizure include losing consciousness, shaking, moving limbs on both sides of the body, and lasts 1-2 minutes. Less commonly, a febrile seizure may only affect one side of the body.
Can High Blood Pressure Hurt My Eyes?
Unfortunately, yes. Suffering from untreated or poorly controlled high blood pressure for a long time can be detrimental to your eyes. Several eye diseases are directly or indirectly caused by high blood pressure (hypertension).
What Causes Congestive Heart Failure?
Congestive heart failure is a chronic disease that progresses with time if left untreated. Heart failure can occur due to diseases of the heart, the blood vessels supplying oxygen and nutrients to the heart, or sometimes from factors outside the heart (extracardiac causes). With proper management, people who have congestive heart failure can lead nearly normal lives, depending on the severity of the condition.
Can You Be Physically Fit and Have High Blood Pressure?
It is entirely possible and common for physically fit people to have high blood pressure (hypertension). Check out the center below for more medical references on high blood pressure, including multimedia (slideshows, images, and quizzes), related disease conditions, treatment and diagnosis, medications, and prevention or wellness.
What Is High Blood Pressure (Hypertension)?
High blood pressure or hypertension is when the blood pressure readings consistently range from 140 or higher for systolic or 90 or higher for diastolic. Blood pressure readings above 180/120 mmHg are dangerously high and require immediate medical attention.
What Happens If You Get High Blood Pressure During Pregnancy?
High blood pressure during pregnancy may result in decreased blood flow to the placenta. Check out the center below for more medical references on high blood pressure, including multimedia (slideshows, images, and quizzes), related disease conditions, treatment and diagnosis, medications, and prevention or wellness.
How Does High Blood Pressure Affect Pregnancy?
High blood pressure during pregnancy can cause serious complications. Learn more about the signs of and risks associated with the condition.
What Causes High Blood Pressure in Children?
Research states that kidney disease is the main cause of high blood pressure in children; however, here are the other potential causes of hypertension in kids.
Treatment & Diagnosis
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Medications & Supplements
- Drugs: Questions to Ask Your Doctor or Pharmacist about Your Drugs
- Drug Interactions
- Types of High Blood Pressure Medications
- Angiotensin II Receptor Blockers (ARBs)
- Congestive Heart Failure Medications
- losartan and hydrochlorothiazide (Hyzaar)
- candesartan cilexetil, Atacand
- Entresto (sacubitril and valsartan)
- telmisartan, Micardis
- Side Effects of Exforge (amlodipine and valsartan)
- Side Effects of Diovan (valsartan)
- valsartan/hydrochlorothiazide (Diovan HCT)
- Types of High Blood Pressure (Hypertension) Medications
- Diovan HCT (valsartan/hydrochlorothiazide) Side Effects, Warnings, and Drug Interactions
Prevention & Wellness
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.