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Medically reviewed by John Cunha, DO
Reference: FDA Prescribing Information
Quick GuideRheumatoid Arthritis (RA) Symptoms & Treatment
Related Disease Conditions
Rheumatoid Arthritis (RA)
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints, the tissue around the joints,...
Arthritis is inflammation of one or more joints. When joints are inflamed they can develop stiffness, warmth, swelling, redness...
Osteoarthritis is a type of arthritis caused by inflammation, breakdown, and eventual loss of cartilage in the joints. Also...
Treatment & Diagnosis
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- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Generic Drugs, Are They as Good as Brand-Names?
- Drugs: Buying Prescription Drugs Online Safely
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Medications & Supplements
- Nonsteroidal Antiinflammatory Drugs (NSAIDs)
- meloxicam (Mobic) Side Effects
- ibuprofen (Advil, Children's Advil/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever, and others)
- indomethacin, Indocin, Indocin-SR (Discontinued Brand in U.S.)
- celecoxib, Celebrex
- diclofenac, Voltaren, Cataflam, Voltaren-XR, Cambia
- nabumetone, Relafen (Discontinued)
- Drug Interactions
- aspirin (acetylsalicylic acid, Bayer, Ecotrin, and others)
- piroxicam, Feldene
- etodolac, Lodine (Discontinued)
- flurbiprofen (Ansaid is a discontinued brand)
- diclofenac and misoprostol, Arthrotec
- sulindac, Clinoril
- oxaprozin, Daypro
- ketoprofen (Discontinued brands: Nexcede, Orudis, Oruvail, Actron)
- fenoprofen, Nalfon
- salsalate, Amigesic, Salflex, Argesic-SA, Marthritic, Salsitab, Artha-G
- tolmetin, Tolectin (Discontinued Brand)
Prevention & Wellness
Daily Health News
Rheumatoid Arthritis Resources
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Reference: FDA Prescribing Information
Top valdecoxib Related ArticlesComplete List
acetylsalicylic acidAspirin (Aspirin, Arthritis Foundation Safety Coated Aspirin, Bayer Aspirin, Bayer Children's Aspirin, Ecotrin, and many others) is a NSAID used to treat fever, pain, and inflammation in the body that results from forms of arthritis, and soft tissue injuries. Aspirin is also used for decreasing the risk of heart attacks and strokes. Side effects, drug interactions, pregnancy information, and pregnancy safety information should be reviewed prior to taking any medication.
ArthritisArthritis is inflammation of one or more joints. When joints are inflamed they can develop stiffness, warmth, swelling, redness and pain. There are over 100 types of arthritis, including osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus, gout, and pseudogout.
celecoxibCelecoxib (Celebrex - Discontinued Brand) is a NSAID (nonsteroidal antiinflammatory drug) that is used to treat pain, arthritis pain, menstrual cramps, and colonic polyps. Celebrex is also used relief of pain, fever, swelling, and tenderness caused by osteoarthritis, juvenile arthritis, rheumatoid arthritis, and ankylosing spondylitis. There are important drug interactions to review when taking Celebrex. Side effects should also be reviewed.
diclofenacDiclofenac (Voltaren, Cataflam, Voltaren-XR, Cambia) is a nonsteroidal anti-inflammatory medication prescribed to treat inflammation and pain caused by conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and menstrual cramps. Side effects, drug interactions, dosage, and pregnancy safety should be reviewed prior to taking this medication.
Drug InteractionsDrug interactions occur frequently. Get facts about the types of drug interactions, what substances or other things that may interact with drugs such as OTC drug and prescription drugs, vitamins, food(s) (grapefruit), and laboratory tests. Find out how to protect yourself from potential drug interactions.
etodolacEtodolac (Lodine ([Discontinued]) is a NSAID prescribed to treat pain and inflammation associated with osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, tendinitis, bursitis, and menstrual cramps. Side effects, drug interactions, and pregnancy safety information should be reviewed prior to taking this medication.
flurbiprofenflurbiprofen (Ansaid - discontinued brand) is a medication prescribed for the treatment of inflammation and pain caused by osteoarthritis, rheumatoid arthritis, soft tissue injuries like bursitis and tendinitis. Side effects, drug interactions, dosage, and pregnancy safety information should be reviewed prior to taking this medication.
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce mild to moderate pain, inflammation, and fever. Ibuprofen works by blocking an enzyme that makes prostaglandin (a hormone-like substance that participates in a variety of body functions), which results in lower levels of prostaglandins in the body. Lower levels of prostaglandins reduce pain, inflammation, and fever.
Ibuprofen is prescribed to treat diseases and conditions that cause mild to moderate pain, fever, and inflammation. For example, Pain from strains and sprains; pain from cuts, scrapes, and puncture wounds; muscle aches and pains; tooth pain; common cold; mild headache; some arthritis conditions; joint pain; and to reduce fever.
Common side effects of ibuprofen include, diarrhea, constipation, nausea, heartburn, belly pain, drowsiness, headaches, tinnitus (ringing in the ears), and mild rash.
More serious side effects and adverse effects include, increased bleeding after injury, stomach ulcers, impaired kidney function, severe allergic reaction (anaphylaxis), blood clots, heart attack, heart failure, and high blood pressure.
The maximum dose prescribed under a doctor's care is 3.2 g daily. Otherwise, the over-the-counter (OTC) maximum daily dose is 1.2 g daily. Dosage depends upon the age, weight, and any current medical conditions of the patient. Several drugs interact with ibuprofen so check with your doctor, pharmacist, or other health care professional with questions in regard to this drug. Doctors don't know if it is safe to take ibuprofen if your are pregnant, therefore it is not recommended if you are pregnant. According to the American Academy of Pediatrics, ibuprofen is safe to take while breastfeeding.
REFERENCE: FDA Prescribing Information.
indomethacinindomethacin; Indocin, Indocin-SR (Discontinued Brand in U.S.) is a nonsteroidal anti-inflammatory (NSAID) drug prescribed for the treatment of inflammation caused by gouty arthritis, osteoarthritis, soft tissue injuries such as bursitis and tendinitis, rheumatoid arthritis, and ankylolsing spondylitis. Side effects, drug interactions, pregnancy safety, and dosage information should be reviewed prior to taking this medication.
meloxicamMeloxicam (Mobic) is a NASAID prescribed for the treatment of swelling, tenderness, and pain caused by the inflammation of arthritis conditions such as osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis in persons over two years of age. Side effects, drug interactions, and pregnancy safety information should be reviewed prior to taking this medication.
nabumetoneNabumetone, Relafen (Discontinued) is a drug prescribed to treat inflammation and pain resulting from rheumatoid arthritis and osteoarthritis. Side effects, drug interactions, and patient safety information should be reviewed prior to taking this medication.
Nonsteroidal Antiinflammatory DrugsNonsteroidal antiinflammatory drugs (NSAIDs) are a class of drugs are used to treat inflammation, mild to moderate pain, and fever. Examples of the most common NSAIDs include: aspirin salsalate (Amigesic), diflunisal (Dolobid), ibuprofen (Motrin), ketoprofen (Orudis), nabumetone (Relafen), piroxicam (Feldene), naproxen (Aleve, Naprosyn,) diclofenac (Voltaren), indomethacin (Indocin), sulindac (Clinoril), tolmetin (Tolectin), etodolac (Lodine), ketorolac (Toradol), oxaprozin (Daypro), celecoxib (Celebrex).
OsteoarthritisOsteoarthritis is a type of arthritis caused by inflammation, breakdown, and eventual loss of cartilage in the joints. Also known as degenerative arthritis. Osteoarthritis can be caused by aging, heredity, and injury from trauma or disease.
piroxicamPiroxicam (Feldene) is a NSAID prescribed for the treatment of rheumatoid arthritis and osteoarthritis. Side effects, drug interactions, warnings and precautions, and pregnancy safety information should be reviewed prior to taking this medication.
Rheumatoid ArthritisRheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints, the tissue around the joints, as well as other organs in the body. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease.