Uremia: Symptoms & Signs

  • Medical Author:
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Medically Reviewed on 9/10/2019

Uremia refers to a clinical syndrome in which there are elevated amounts of urea in the blood. The syndrome causes fluid and electrolyte imbalances as well as hormonal imbalances.

Symptoms associated with uremia include nausea, vomiting, fatigue, appetite loss, weight loss, itching, muscle cramps, thirst, visual disturbances, and changes in mental status. Other associated symptoms and signs can include low urine output, confusion, hiccups, and high blood pressure. Serious complications can include seizure, cardiac arrest due to electrolyte imbalances, coma, and bleeding into the brain or gastrointestinal tract.

Causes of uremia

Chronic kidney disease or failure is the most common cause of uremia, but it can also occur in severe cases of acute or sudden damage to the kidneys.

Other Causes of Uremia Symptoms and Signs

REFERENCE:

Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.

SLIDESHOW

Kidney Stones: Symptoms, Causes, and Treatment See Slideshow

Subscribe to MedicineNet's General Health Newsletter

By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time.

Medically Reviewed on 9/10/2019
References
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.