GENERIC NAME: TRICYCLIC ANTIDEPRESSANTS - ORAL, INJECTION
Medication Uses | Other Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
USES: This medication is used to treat depression, obsessive- compulsive disorders, and bed-wetting in children over 6 years of age (enuresis).
OTHER USES: This medication may also be used to treat nerve pain, sleeping problems (insomnia), and has other uses as determined by your doctor.
HOW TO USE: Use this as prescribed. Try to use each dose at the same time(s) each day so you remember to routinely use it. It may take 2 to 3 weeks before the full benefit of this medication becomes apparent. Do not stop using this medication without your doctor's approval. Nausea, headache or fatigue can occur if the drug is suddenly stopped.
SIDE EFFECTS: May cause drowsiness, dizziness, increased sun sensitivity or blurred vision. May initially cause dizziness and lightheadedness when rising too quickly from a sitting or lying position. Other side effects include heartburn, loss of appetite, dry mouth, strange taste in mouth, anxiety, restlessness or sweating. If any side effects persist or worsen, notify your doctor. Report promptly: chest pain, rapid or irregular heartbeat, difficulty urinating, nightmares, ringing in the ears, excessive drowsiness, uncoordinated movements, fainting. Taking this medication at bedtime may help minimize side effects. Talk to your doctor about this. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before using this drug tell your doctor your medical history, especially of: glaucoma, prostate problems, decreased urine output, thyroid disease, breathing problems, seizure problems, alcohol use, heart disease, mental/emotional problems, liver or kidney disease, any drug allergies. Use caution when engaging in tasks requiring alertness such as driving or operating machinery. Limit alcohol consumption as it may increase the drowsiness and dizziness effects of this drug. Limit exposure to hot weather as it may lead to heat stroke. Though uncommon, depression itself can lead to thoughts or attempts of suicide. Tell your doctor immediately if you have any suicidal thoughts, or other mental/mood changes. Keep all medical appointments so your doctor can monitor your progress closely. Caution is advised when using this drug in the elderly, because they may be more sensitive to the effects of the drug (e.g., confusion may occur or worsen). This drug should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor. This drug may be excreted into breast milk. The effects on the infant are not known at this time. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Inform your doctor about the medicines you take, especially if you take: clonidine, guanadrel, guanethidine, MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), cimetidine, SSRIs (e.g., fluoxetine, sertraline), warfarin, carbamazepine, certain diet pills (e.g., phentermine, fenfluramine), adrenaline-type drugs (e.g., dopamine, ephedrine, epinephrine, pseudoephedrine, phenylephrine, isoproterenol- some of which may be found in cough-and-cold or asthma products), narcotic pain medications (e.g., codeine), cisapride, St John's wort, heart rhythm drugs (e.g., quinidine, flecainide, propafenone), phenothiazines (e.g., chlorpromazine), any other prescription or nonprescription drugs you take. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include agitation, confusion, hallucinations, fever, irregular movement of the eyes, seizures, change in amount of urine, dry mouth or nose, constipation, large pupils, drowsiness, slow or shallow breathing, dizziness, unconsciousness, unusually fast or slow heartbeat, or flushing..
NOTES: Do not allow anyone else to use this medication.
MISSED DOSE: If you miss a dose and are taking more than 1 daily: do not take it if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. If you take it once daily at bedtime, do not take it the following morning. Call your doctor. Do not double the dose to catch up.
STORAGE: Store at room temperature away from moisture and sunlight. Do not store in the bathroom. Do not freeze liquid forms of this medication.
Related Disease Conditions
Irritable Bowel Syndrome (IBS)
Irritable bowel syndrome or IBS is a GI disorder with symptoms of constipation, abdominal pain, bloating, and gas. IBS treatment includes medications, dietary changes, and lifestyle changes.
Migraine headache is a type of headache associated with a sensitivity to light, smells, or sounds, eye pain, severe pounding on one side of the head, and sometimes nausea and vomiting. The exact cause of migraine headaches is not known. Triggers for migraine headaches include certain foods, stress, hormonal changes, strong stimuli (loud noises), and oversleeping. Treatment guidelines for migraines include medicine, pain management, diet changes, avoiding foods that trigger migraines, staying hydrated, getting adequate sleep, and exercising regularly. Prevention of migraine triggers include getting regular exercise, drinking water daily, reducing stress, and avoiding trigger foods.
Vaginal Pain (Vulvodynia)
Vulvodynia or vaginal pain, genital pain is a condition in which women have chronic vulvar pain with no known cause. There are two types of vulvodynia, generalized vulvodynia, and vulvar vestibulitis. Researchers are trying to find the causes of vulvodynia, for example, nerve irritation, genetic factors, hypersensitivity to yeast infections, muscle spasms, and hormonal changes. The most common symptoms of vaginal pain (vulvodynia) are burning, rawness, itching, stinging, aching, soreness, and throbbing. There are a variety of treatments that can ease the symptoms of vulvodynia (vaginal pain).
Depression is an illness that involves the body, mood, and thoughts and affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. The principal types of depression are major depression, dysthymia, and bipolar disease (also called manic-depressive disease).
Alzheimer's disease is a common cause of dementia. Symptoms and warning signs of Alzheimer's disease include memory loss, difficulty performing familiar tasks, disorientation to time and place, misplacing things, and more. The biggest risk factor for Alzheimer's disease is increased age. Treatment for Alzheimer's is often targeted toward decreasing the symptoms and progression of the disease.
People with bulimia nervosa, an eating disorder that involves episodes of bingeing and purging, experience symptoms and signs such as deteriorating teeth, sore throat, constipation, thinning hair, and dehydration. Treatment of bulimia may involve cognitive behavior therapy, family therapy, nutritional counseling, and medication.
Treatment & Diagnosis
Medications & Supplements
Prevention & Wellness
- What Is Avascular Necrosis and How Does It Affect Bones?
- The Arch of the Human Foot Was Key to Upright Walking, Scientists Say
- Worried About Cataracts? Here's What You Need to Know
- FDA Issues Warning About Compounded Versions of Wegovy, Ozempic
- Sick Restaurant Workers Fuel Many Foodborne Illness Outbreaks
- More Health News »
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.