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- What is triamcinolone acetonide nasal inhaler-spray, and how does it work (mechanism of action)?
- What are the side effects of triamcinolone acetonide nasal inhaler-spray?
- What is the dosage for triamcinolone acetonide nasal inhaler-spray?
- Which drugs or supplements interact with triamcinolone acetonide nasal inhaler-spray?
- Is triamcinolone acetonide nasal inhaler-spray safe to take if I'm pregnant or breastfeeding?
- What else should I know about triamcinolone acetonide nasal inhaler-spray?
What is triamcinolone acetonide nasal inhaler-spray, and how does it work (mechanism of action)?
Triamcinolone acetonide is a synthetic (man-made) corticosteroid. It is administered either as an oral metered-dose inhaler for the treatment of asthma (Azmacort), as a topical preparation for the skin (Kenalog; Aristocort) or as a nasal spray (Nasacort AQ) for relieving symptoms of rhinitis. Corticosteroids are naturally occurring hormones produced by the adrenal glands that prevent or suppress inflammation and immune responses. When given by intranasal spray, triamcinolone acetonide provides relief from allergy-induced watery nasal discharge (rhinorrhea), nasal congestion, postnasal drip, sneezing, and itching of the back of the throat which are symptoms associated with allergy. Approximately 50% of the triamcinolone acetonide is absorbed into the blood. A beneficial response usually is noted within a few days but can take as long as 4 weeks. The FDA approved Nasacort in July 1991.
What brand names are available for triamcinolone acetonide nasal inhaler?
Nasacort (discontinued brand in USA), Nasacort AQ
Is triamcinolone acetonide nasal inhaler available as a generic drug?
Do I need a prescription for triamcinolone acetonide nasal inhaler-spray?
What are the side effects of triamcinolone acetonide nasal inhaler-spray?
The most common side effects following nasal inhalation of triamcinolone acetonide are nasal irritation and itching, increased cough, nausea or vomiting, sore throat, nasal congestion, sneezing, nasal burning, bloody nasal discharge, and nasal dryness. Other adverse effects reported with intranasal triamcinolone acetonide include headache, dizziness, and watery eyes. All of these are either mild or uncommon. Nasal septal perforation, oral or nasal fungal infections, growth suppression in children, glaucoma, cataracts, and decreased production of cortisol by the adrenal glands also may occur.
What is the dosage for triamcinolone acetonide nasal inhaler-spray?
The recommended dose is one or two sprays in each nostril once daily. Before use of the nasal spray, the nose should be blown gently, and the inhaler or spray should be shaken. The head should be tilted backwards, with the nozzle inserted into one nostril, the opening of the nozzle toward the swollen area. The other nostril should be closed. and the spray or inhaler activated while breathing in through the nose and out through the mouth. The inhaler or spray should be cleaned daily. The canister should be removed from the inhaler, rinsing the cap, nosepiece, and the inhaler with warm water and then drying them thoroughly.
Which drugs or supplements interact with triamcinolone acetonide nasal inhaler-spray?
No drug interactions have been described with nasal triamcinolone.
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Is triamcinolone acetonide nasal inhaler-spray safe to take if I'm pregnant or breastfeeding?
Serious complications (including cleft palate and still births) have been reported when oral corticosteroids were administered during pregnancy. It is not known if the small amounts of corticosteroids that appear in the blood following intranasal use carry the same risk. Triamcinolone acetonide use during pregnancy should be avoided unless the physician feels that the potential therapeutic benefit justifies the potential risk to the fetus.
It is unknown whether triamcinolone acetonide accumulates in breast milk. However, it is known that other corticosteroids are excreted in breast milk. The effects on the child, if any, are unknown.
What else should I know about triamcinolone acetonide nasal inhaler-spray?
What preparations of triamcinolone acetonide nasal inhaler-spray are available?
Nasal Spray: 16.5 g, 120 actuations. Each spray delivers 55 mcg triamcinolone acetonide.
How should I keep triamcinolone acetonide nasal inhaler-spray stored?
Triamcinolone spray should be stored at room temperature, 59-86 F (15-30 C), and protected from heat, and direct light.
Triamcinolone acetonide nasal inhaler-spray (Nasacort [discontinued brand in USA]; Nasacort AQ) is a medication prescribed for relieving the symptoms of rhinitis. Side effects, dosage, and drug interactions should be reviewed prior to taking this medication.
Related Disease Conditions
Chronic Rhinitis and Post-Nasal Drip
Chronic rhinitis and post-nasal drip symptoms include an itchy, runny nose, sneezing, itchy ears, eyes, and throat. Seasonal allergic rhinitis (also called hay fever) usually is caused by pollen in the air. Perennial allergic rhinitis is a type of chronic rhinitis and is a year-round problem, often caused by indoor allergens, such as dust, animal dander, and pollens that may exist at the time. Treatment of chronic rhinitis and post nasal drip are dependent upon the type of rhinitis condition.
An allergy refers to a misguided reaction by our immune system in response to bodily contact with certain foreign substances. When these allergens come in contact with the body, it causes the immune system to develop an allergic reaction in people who are allergic to it. It is estimated that 50 million North Americans are affected by allergic conditions. The parts of the body that are prone to react to allergies include the eyes, nose, lungs, skin, and stomach. Common allergic disorders include hay fever, asthma, allergic eyes, allergic eczema, hives, and allergic shock.
Asthma is a condition in which hyperreactive airways constrict and result in symptoms like wheezing, coughing, and shortness of breath. Causes of asthma include genetics, environmental factors, personal history of allergies, and other factors. Asthma is diagnosed by a physician based on a patient's family history and results from lung function tests and other exams. Inhaled corticosteroids (ICS) and long-acting bronchodilators (LABAs) are used in the treatment of asthma. Generally, the prognosis for a patient with asthma is good. Exposure to allergens found on farms may protect against asthma symptoms.
Hay Fever (Allergic Rhinitis)
Hay fever (allergic rhinitis) is an irritation of the nose caused by pollen and is associated with the following allergic symptoms: nasal congestion, runny nose, sneezing, eye and nose itching, and tearing eyes. Avoidance of known allergens is the recommended treatment, but if this is not possible, antihistamines, decongestants, and nasal sprays may help alleviate symptoms.
Allergy Treatment Begins at Home
Avoiding allergy triggers at home is one of the best ways to prevent allergy symptoms. Controlling temperature, humidity, and ventilation are a few ways to allergy-proof the home. Cleaning, vacuuming, and using HEPA air filters also helps control allergies.
What Causes Chronic Sinusitis?
Chronic sinusitis occurs when the tissue lining the facial sinuses becomes inflamed for at least three months. Chronic sinusitis usually involves nasal airway swelling (rhinitis). The causes of chronic sinusitis include nasal polyps, deviated nasal septum, medical conditions, respiratory tract infections, and allergies.
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