- What is triamcinolone acetonide inhaler, and how does it work (mechanism of action)?
- What are the side effects of triamcinolone acetonide inhaler?
- What is the dosage for triamcinolone acetonide inhaler?
- Which drugs or supplements interact with triamcinolone acetonide inhaler?
- Is triamcinolone acetonide inhaler safe to take if I'm pregnant or breastfeeding?
- What else should I know about triamcinolone acetonide inhaler?
What is triamcinolone acetonide inhaler, and how does it work (mechanism of action)?
Triamcinolone is a synthetic (man-made) steroid of the glucocorticoid family used for treating asthma. It is similar to beclomethasone (Vanceril, QVAR) and fluticasone (Flovent). The naturally-occurring glucocorticoid hormone is cortisol or hydrocortisone produced in the adrenal glands. Glucocorticoids have potent anti-inflammatory actions. Some symptoms of asthma are caused by chronic inflammation in the airways within the lungs that obstruct the flow of air into and out of the lungs. Triamcinolone reduces inflammation in the lungs and airways and thereby improves breathing in individuals with asthma. When used as an inhaler, triamcinolone goes directly to the airways of the lungs, and very little is absorbed into the body. The FDA approved the triamcinolone inhaler in April 1982.
Is triamcinolone acetonide inhaler available as a generic drug?
GENERIC AVAILABLE: No
Do I need a prescription for triamcinolone acetonide inhaler?
What are the side effects of triamcinolone acetonide inhaler?
Common side effects are:
Mild cough or wheezing due to chemical irritation may be minimized by using an inhaled bronchodilator, for example, albuterol (Ventolin), prior to using the triamcinolone. Oral candidiasis or thrush (a fungal infection) may occur in 1 in 20 to 1 in 10 persons who use triamcinolone, the risk being higher with higher doses. The risk of thrush in children is lower than in adults. Hoarseness also may result from the use of triamcinolone inhaler. Using a spacer (a device that is attached to the inhaler) and washing the mouth out with water following each use reduces the risk of thrush and hoarseness.
High doses of inhaled glucocorticoids may decrease the formation of bone and increase the breakdown (resorption) of bone leading to weak bones and fractures. Very high doses may cause suppression of the body's ability to make its own natural glucocorticoid in the adrenal glands. It is possible that patients with suppression of their adrenal glands may need increased amounts of glucocorticoids by the oral or intravenous route during periods of high physical stress such as illnesses when increased amounts of glucocorticoids are needed by the body.
What is the dosage for triamcinolone acetonide inhaler?
The usual recommended dosage for adults is two inhalations (150 mcg) given 3-4 times daily or 4 inhalations (300 mcg) given twice daily. The maximum daily dose is 16 inhalations (1200 mcg) in adults. Higher initial doses (12 to 16 inhalations per day) may be considered in patients with more severe asthma.
The usual recommended dosage for children (6-12 years old) is 1 or 2 inhalations.
(75 to 150 mcg) given 3-4 times daily or 2-4 inhalations (150 to 300 mcg) twice daily. The maximum daily dose is 12 inhalations (900 mcg).
Which drugs or supplements interact with triamcinolone acetonide inhaler?
No drug interactions have been described with inhaled triamcinolone.
Is triamcinolone acetonide inhaler safe to take if I'm pregnant or breastfeeding?
There are no adequate studies of the triamcinolone inhaler in pregnant women.
It is not known if triamcinolone is secreted in breast milk. Other medications in its family are secreted into breast milk, but it is not known whether the small amounts that may appear in milk affect the infant.
What else should I know about triamcinolone acetonide inhaler?
What preparations of triamcinolone acetonide inhaler are available?
Metered Dose Inhaler: 60 mg (75 mcg/actuation)
How should I keep triamcinolone acetonide inhaler stored?
Triamcinolone inhaler should be kept at room temperature, 20 C - 25 C (68 F - 77 F) and protected from direct light. Exposure to temperatures above 38.8 C (120 F) may cause bursting of the canister. The canister should never be thrown into a fire or incinerator.
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Triamcinolone inhaler (Azmacort) is a glucocorticoid steroid medication used for the treatment of asthma. Triamcinolone inhaler (Azmacort) should not be used for acute asthma attacks. Review side effects, drug interactions, warnings and precautions, and patient safety information prior to taking this medication.
Related Disease Conditions
Asthma is a condition in which hyperreactive airways constrict and result in symptoms like wheezing, coughing, and shortness of breath. Causes of asthma include genetics, environmental factors, personal history of allergies, and other factors. Asthma is diagnosed by a physician based on a patient's family history and results from lung function tests and other exams. Inhaled corticosteroids (ICS) and long-acting bronchodilators (LABAs) are used in the treatment of asthma. Generally, the prognosis for a patient with asthma is good. Exposure to allergens found on farms may protect against asthma symptoms.
COPD (Chronic Obstructive Pulmonary Disease)
COPD or chronic obstructive pulmonary disease is a lung condition caused by smoking tobacco, exposure to secondhand smoke, and/or air pollutants. Conditions that accompany COPD include chronic bronchitis, chronic cough, and emphysema. Symptoms of COPD include shortness of breath, wheezing, and chronic cough. Treatment of COPD includes GOLD guidelines, smoking cessation, medications, and surgery. The life expectancy of a person with COPD depends on the stage of the disease.
Asthma: Over the Counter Treatment
Patients who have infrequent, mild bouts of asthma attacks may use over-the-counter (OTC) medications to treat their asthma symptoms. OTC asthma medicines are limited to epinephrine and ephedrine. These OTC drugs are best used with the guidance of a physician, as there may be side effects and the drugs may not be very effective.
There are many unusual symptoms of asthma, including sighing, difficulty sleeping, anxiety, chronic cough, recurrent walking pneumonia, and rapid breathing. These symptoms may vary from individual to individual. These asthma complexities make it difficult to accurately diagnose and treat asthma.
Asthma in Children
Asthma in children manifests with symptoms such as coughing and wheezing. Rates of asthma in children are increasing. Asthma in children is usually diagnosed based on the description of symptoms. Lung function tests may also be used. A variety of medications are used for the treatment of childhood asthma.
There are two types of asthma medications: long-term control with anti-inflammatory drugs and quick relief from bronchodilators. Asthma medicines may be inhaled using a metered-dose inhaler or nebulizer or they may be taken orally. People with high blood pressure, diabetes, thyroid disease, or heart disease shouldn't take OTC asthma drugs like Primatene Mist and Bronkaid.
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.