Toxic Shock Syndrome (TSS): Symptoms & Signs

Medically Reviewed on 9/10/2019

Toxic shock syndrome (TSS) is a severe illness that can cause widespread organ dysfunction. TSS has been associated with certain bacterial infections.

Associates symptoms and signs of toxic shock syndrome can include high fever, chills, low blood pressure, rash, skin peeling, dizziness, lightheadedness, fainting, headache, fatigue, vomiting, trouble breathing, muscle aches, problems with blood clotting, and problems with kidney and liver function. Kidney failure can lead to insufficient urine production.

Causes of toxic shock syndrome

Exotoxins secreted by Streptococcus or Staphylococcus bacteria cause toxic shock syndrome. Some early outbreaks were described in women who used tampons during menstruation, but the majority of cases do not arise from tampon use. Other possible risk factors for developing TSS include deep wound infections and decreased immune function.

Other toxic shock syndrome (tss) symptoms and signs


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Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.