Type of Drug: Protease Inhibitor
Once HIV has infected a cell and made copies of itself, it uses an enzyme called protease to process itself correctly so it can be released from the cell to infect other cells. Protease inhibitors work by blocking that enzyme.
Approved adult dosing
Notes on taking this medication
- Should take with food; high-fat meal increases absorption
- Must take with Norvir
- Aptivus interacts with many other drugs; persons using Aptivus with those drugs may need an adjustment to their dose of Aptivus or the other drugs; consult your medical provider
- Abdominal pain; nausea; vomiting; diarrhea
- Elevations in cholesterol and triglycerides
- Liver inflammation and increased liver enzyme levels
SOURCE: United States Department of Veterans Affairs. "Drug Dosing Toolkit, Aptivus (tipranavir)."
Quick GuideHIV AIDS Facts: Symptoms and Treatments
Aptivus (tipranavir) is a protease inhibitor prescribed for the treatment of human immunodeficiency virus (HIV). Side effects, drug interactions, warnings and precautions, and patient information should be reviewed prior to taking any medication.
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Protease Inhibitors (PI) Drug Class
Protease Inhibitors (PIs) are a class of antiviral drugs prescribed to treat HIV and hepatitis (HCV) viral infections. There are several protease inhibitors that treat HIV infection, for example:
- Lexiva (fosamprenavir)
- Invirase (saquinavir)
- Kaletra (lopinavir/ritonavir)
- Viracept (nelfinavir)
- Norvir (ritonavir)
Examples of hepatitis C virus protease inhibitors include:
- Olysio (simeprevir)
- Technivie (ombitasvir/paritaprevir and ritonavir, a combination of these three drugs)
- Viekira Pak (ombitasvir/paritaprevir/ritonavir and dasabuvir, a combination of these four drugs)
Drug interactions, dosage, preparations, and pregnancy and breastfeeding safety should be reviewed prior to taking these drugs.
ritonavirRitonavir (Norvir) is a drug used in combination with other drugs for the treatment of HIV infection. Side effects, drug interactions, and dosing information should be reviewed prior to taking this medication.