- What is testosterone gel-topical, and how does it work (mechanism of action)?
- What brand names are available for testosterone gel-topical?
- Is testosterone gel-topical available as a generic drug?
- Do I need a prescription for testosterone gel-topical?
- What are the side effects of testosterone gel-topical?
- Which drugs or supplements interact with testosterone gel-topical?
- Is testosterone gel-topical safe to take if I'm pregnant or breastfeeding?
- What else should I know about testosterone gel-topical?
What is testosterone gel-topical, and how does it work (mechanism of action)?
Androgel is a gel containing testosterone. It is administered through the skin for treatment of low testosterone levels. It belongs to a class of drugs called androgens. Other testosterone replacement products include Androderm, Axiron, Testim, and Fortesta. Testosterone is the major male sex hormone responsible for the normal growth and development of the male sex organs and secondary sex characteristics. These effects include development of the prostate, penis, and scrotum; distribution of facial, pubic, chest and axillary hair; development of a deep voice and alterations in muscle mass and fat distribution. Low production of testosterone leads to erectile dysfunction, reduced sexual desire, fatigue and loss of energy, depression, regression of secondary sexual characteristics, and weakening of bones (osteoporosis). Androgel and other testosterone replacement products supplement or replace natural production of testosterone and reverse symptoms of low testosterone levels. The FDA approved Androgel in February 2000.
What are the side effects of testosterone gel-topical?
The most common side effects of Androgel are:
Which drugs or supplements interact with testosterone gel-topical?
: Testosterone may decrease blood glucose levels. Therefore, less insulin may be required in diabetic patients. Testosterone may increase the action of the blood thinner warfarin (Coumadin), increasing the risk of bleeding. Combining steroids with testosterone may increase fluid retention.
Quick GuideLow Testosterone (Low T) Treatments
Is testosterone gel-topical safe to take if I'm pregnant or breastfeeding?
Androgel should not be used by nursing mothers because of the possibility of adverse effects in the nursing infant.
What else should I know about testosterone gel-topical?
What preparations of testosterone gel-topical are available?
1% Solution; 1.62% solution; 20 mg/1.25gm: 25 mg/2.5 gm; 40.5 mg/2.5gm: 50 mg/5 g, 1%: 1.62%.
How should I keep testosterone gel-topical stored?
Androgel should be stored at room temperature 15 C to 30 C (59 F to 86 F)DOSING: The recommended starting dose is 50 mg applied once daily to the skin of shoulders, upper arm, or abdomen. The dose may be increased based on blood testosterone levels. The hands should be washed thoroughly with soap and water after applying Androgel.
REFERENCE: FDA Prescribing Information.
Testosterone gel (Androgel) is a gel containing testosterone and is prescribed for the treatment of low testosterone levels. Side effects, drug interactions, and patient safety information should be reviewed prior to taking this medication.
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DepressionDepression is an illness that involves the body, mood, and thoughts and affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. The principal types of depression are major depression, dysthymia, and bipolar disease (also called manic-depressive disease).
Depression in the ElderlyDepression in the elderly is very common. That doesn't mean, though, it's normal. Treatment may involve antidepressants, psychotherapy, or electroconvulsive therapy.
Erectile Dysfunction (ED, Impotence)Erectile dysfunction (ED, impotence) is the failure to achieve or maintain an erection. There are many potential underlying causes of erectile dysfunction, including stress and emotional problems, brain dysfunction, problems with blood supply to the penis, and structural problems with the penis. Erectile dysfunction is diagnosed by taking the patient's history and physical exam. Blood tests measuring kidney function and blood sugar, cholesterol, hormone, and prostate-specific antigen (PSA) levels may be ordered. Urinalysis, ultrasound, and other more sophisticated tests may be required. The treatment of erectile dysfunction depends on the underlying cause. Medications, penile injections, penile implants, and vacuum devices may be used. Treatment for erectile dysfunction is usually successful. The patient should manage heart disease risk factors (high blood pressure, high cholesterol, diabetes) as they are related to erectile dysfunction risk.
Low Testosterone (Low T)
Low testosterone (low-T) can be caused by conditions such as type 2 diabetes, obesity, liver or kidney disease, hormonal disorders, certain infections, and hypogonadism. Signs and symptoms that a person may have low-T include:
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- Weight gain
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- Decreased sex drive
- Worsening of congestive heart failure or sleep apnea.
Low-T can be treated with testosterone therapy in the form of gels, injections, pellets, or skin patches. Side effects of testosterone treatment include:
- Hair loss
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OsteoporosisLearn about osteoporosis, a condition characterized by the loss of bone density, which leads to an increased risk of bone fracture. Unless one experiences a fracture, a person may have osteoporosis for decades without knowing it. Treatment for osteoporosis may involve medications that stop bone loss and increase bone strength and bone formation, as well as quitting smoking, regular exercise, cutting back on alcohol intake, and eating a calcium- and vitamin D-rich balanced diet.
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Testosterone Therapy to Treat EDThe testicles produce testosterone a hormone responsible for the proper development of male sexual characteristics. Testosterone is also important for maintaining muscle bulk, adequate levels of red blood cells, bone growth, sense of well-being and sexual function. As a man ages, the amount of testosterone in his body gradually declines and the significance of testosterone decline is controversial and poorly understood. The treatment for testosterone deficiency can include intramuscular injections, generally every two or three weeks, testosterone patch worn either on the body or on the scrotum, testosterone gel, mucoadhesive material applied above the teeth twice a day, or oral tablets.
testosterone topical solution (Axiron)Testosterone topical solution (Axiron) is a testosterone solution that is administered through the skin of the armpit to treat low levels of testosterone. Side effects, drug interactions, and patient safety information should be reviewed prior to taking this medication.