terconazole, Terazol, Zazole

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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What is terconazole, and how does it work (mechanism of action)?

Terconazole is an anti-fungal cream and suppository used for treating vaginal yeast infections (Candida). It is related to several other anti-fungal drugs including fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), miconazole (Micatin, Monistat), and clotrimazole (Lotrimin). It prevents growth of yeast by preventing production of the membranes that surround the yeast cells. The FDA approved terconazole in December 1987.

What brand names are available for terconazole?

Terazol 3, Terazol 7

Is terconazole available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for terconazole?

Yes

What are the side effects of terconazole?

The most common side effects associated with terconazole are irritation, increased sensitivity and burning of the vulvae or vagina. Other side effects include headache, painful menstrual periods, aches, abdominal pain, fever, chills, and itching.

What is the dosage for terconazole?

One applicator full of the 0.4% vaginal cream should be applied into the vagina at bedtime for 7 days. One applicator full of the 0.8% vaginal cream or one vaginal suppository should be applied at bedtime for 3 days.

Which drugs or supplements interact with terconazole?

: There are no known drug interactions with topical terconazole.

Is terconazole safe to take if I'm pregnant or breastfeeding?

It is not known if terconazole is secreted in breast milk.

What else should I know about terconazole?

What preparations of terconazole are available?

Vaginal cream: 0.4 and 0.8%. Vaginal suppositories: 80 mg.

How should I keep terconazole stored?

Terconazole should be stored at room temperature, 15 C - 30 C (59 F - 86 F).

Reference: FDA Prescribing Information

Summary

Terconazole (Terazol, Zazole) is an anti-fungal cream and suppository prescribed for the treatment of vaginal yeast infections (Candida). Side effects, warnings and precautions, drug interactions, and safety during pregnancy should be reviewed prior to taking this medication.

Treatment & Diagnosis

Medications & Supplements

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See more info: terconazole on RxList
Reviewed on 10/27/2014
References
Reference: FDA Prescribing Information

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