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- What is Flomax (tamsulosin) drug?
- Why is Flomax (tamsulosin) prescribed to patients?
- Do I need a prescription for Flomax (tamsulosin)?
- Is Flomax (tamsulosin) available as a generic drug?
- What are the side effects of Flomax (tamsulosin)?
- What is the dosage for Flomax (tamsulosin)?
- Which drugs or supplements interact with Flomax (tamsulosin)?
- Is Flomax (tamsulosin) safe to use during pregnancy or while breastfeeding?
- What else should I know about Flomax (tamsulosin)?
What is Flomax (tamsulosin) drug?
Flomax (tamsulosin) is an oral drug for the treatment of men who are having difficulty urinating because of enlarged prostates from benign prostatic hyperplasia (BPH).
Why is Flomax (tamsulosin) prescribed to patients?
What are the side effects of Flomax (tamsulosin)?
The most common adverse effects of Flomax are
- anemia (decreased red blood cells),
- decreased white blood cells,
- abnormal taste,
- increased triglycerides, and
Other side effects include
- low blood pressure,
- abdominal pain,
- weight loss,
- muscle pain,
- abnormal ejaculation,
- upper respiratory tract infections, and
More serious side effects of Flomax
The following have been observed in male patients during Flomax treatment:
What is the dosage for Flomax (tamsulosin)?
- The recommended starting dose is 0.4 once daily about 30 minutes after the same meal time each day.
- When taken on an empty stomach, more of the medication is absorbed.
- This could cause a greater effect and potentially a drop in blood pressure.
- The dose may be increased to 0.8 mg once daily after 2 to 4 weeks if the response is not adequate.
- The capsules should not be crushed, chewed or opened.
Which drugs or supplements interact with Flomax (tamsulosin)?
The elimination of Flomax from the body may be reduced by:
- ketoconazole (Nizoral, Extina, Xolegel, Kuric),
- paroxetine (Paxil),
- cimetidine (Tagamet),
- ritonavir (Norvir),
- lopinavir, and
- other drugs that reduce the elimination of drugs by liver enzymes.
Reduced elimination may lead to increased side effects of Flomax. PDE-5 inhibitors (for example, vardenafil [Levitra, Staxyn], Adcirca, sildenafil [Viagra, Revatio], tadalafil [Cialis]) add to the blood pressure lowering effects of Flomax and may result in severe blood pressure reduction.
Is Flomax (tamsulosin) safe to use during pregnancy or while breastfeeding?
- Flomax is not prescribed for women.
- This medication is used only in men. It is not known if Flomax is secreted into human milk.
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What else should I know about Flomax (tamsulosin)?
What preparations of Flomax (tamsulosin) are available?
Capsules: 0.4 mg.
How should I keep Flomax (tamsulosin) stored?
Capsules should be stored at room temperature, 15 C to 30 C (59 F to 86 F).
How does Flomax (tamsulosin) work?
- In men, the tube which carries urine from the bladder through the penis (called the urethra) passes through the prostate gland. As men get older, the prostate gland enlarges, and the muscle cells within the prostate gland and the neck of the bladder (which controls the flow of urine) tighten. The combination of enlargement and tightening of muscles compresses the urethra and obstructs the flow of urine. This results in difficulty urinating and retention of urine within the bladder. The tightening or contraction of the muscle cells is controlled by nerves. One type of nerve, the alpha adrenergic nerves, cause the muscle cells to tighten by releasing a chemical related to epinephrine (adrenalin). Tamsulosin blocks the effects of this chemical on the muscle cells and causes the muscles to relax. This results in a decrease in obstruction to the flow of urine.
- There are other drugs that block alpha adrenergic nerves throughout the body and which are used in treating diseases of the heart, blood vessels, and prostate for example, prazosin (Minipress), terazosin (Hytrin), doxazosin (Cardura), and alfuzosin (Uroxatral). Tamsulosin is more active against the alpha adrenergic nerves of the prostate and bladder neck than these other drugs and has a lesser effect on alpha adrenergic nerves elsewhere in the body. For this reason, tamsulosin causes fewer side effects, especially low blood pressure, than other alpha adrenergic blocking drugs. Moreover, tamsulosin therapy can be started at the optimum dose whereas other alpha adrenergic blocking drugs need to be started at low doses with the doses slowly increased over time in order to minimize the side effects.
When was Flomax (tamsulosin) approved by the FDA?
Tamsulosin was approved by the FDA in 1997.
Flomax (tamsulosin) is a drug prescribed for the treatment of benign prostatic hyperplasia (BPH, enlarged prostate). Side effects may include:
- Low blood pressure
- Increased triglycerides
- Abnormal ejaculation
- Upper respiratory tract infections
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Related Disease Conditions
Kidney Stones (nephrolithiasis)
Kidney stones are solid masses of crystalline material that form in the kidneys. Symptoms of kidney stones can include pain, nausea, vomiting, and even fever and chills. Kidney stones are diagnosed via CT scans and specialized X-rays. Treatment of kidney stones involves drinking lots of fluids and taking over-the-counter pain medications to medical intervention including prescription medications, lithotripsy, and sometimes even surgery.
Prostatitis (Inflammation of the Prostate Gland)
Prostatitis is an inflammation of the prostate gland. Signs and symptoms of prostatitis include painful or difficulty urinating; fever; chills; body aches; blood in the urine; pain in the rectum, groin, abdomen, or low back; and painful ejaculation or sexual dysfunction. Causes of prostatitis include STDs, bacteria from urinary tract infections, or E. coli. Treatment for prostatitis depends on if it is a bacterial infection or chronic inflammation of the prostate gland.
Enlarged Prostate (BPH, Benign Prostatic Hyperplasia)
Benign prostatic hyperplasia (BPH or enlarged prostate) is very common in men over 50 years of age. Half of all men over the age of 50 develop symptoms of BPH, but few need medical treatment. This noncancerous enlargement of the prostate can impede urine flow, slow the flow of urine, create the urge to urinate frequently and cause other symptoms like complete blockage of urine and urinary tract infections. More serious symptoms are urinary tract infections (UTIs) and complete blockage of the urethra, which may be a medical emergency. BPH is not cancer. Not all men with the condition need treatment, and usually is closely monitored if no symptoms are present. Treatment measures usually are reserved for men with significant symptoms, and can include medications, surgery, microwave therapy, and laser procedures. Men can prevent prostate problems by having regular medical checkups that include a prostate exam.
There are many types of urinary incontinence (UI), which is the accidental leakage of urine. These types include stress incontinence, urge incontinence, and overflow incontinence. Urinary incontinence in men may be caused by prostate or nerve problems. Treatment depends upon the type and severity of the UI and the patient's lifestyle.
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