- Heartburn Slideshow: Foods to Eat, Foods to Avoid
- 10 Facts About the Amazing Brain
- Weight Gain Shockers Slideshow Pictures
- What brand names are available for tacrolimus?
- Is tacrolimus available as a generic drug?
- Do I need a prescription for tacrolimus?
- What are the uses for tacrolimus?
- What are the side effects of tacrolimus?
- What is the dosage for tacrolimus?
- Is tacrolimus safe to take if I'm pregnant or breastfeeding?
- What else should I know about tacrolimus?
What are the uses for tacrolimus?
What are the side effects of tacrolimus?
Tacrolimus is associated with many and various side effects. These include:
- loss of appetite,
- high concentrations of potassium in the blood,
- high blood pressure,
- tingling sensation in the extremities,
- high blood sugar concentrations, and
- abdominal pain.
Other side effects include
Quick GuidePrescription Drug Abuse: Know The Warning Signs
What is the dosage for tacrolimus?
- Oral tacrolimus is taken twice daily.
- Starting doses range between 0.075 mg/kg/day to 0.2 mg/kg/day (immediate release capsules).
- Doses vary widely and are based on tests that measure the amount of tacrolimus in the blood.
- Taking tacrolimus with food can reduce some of the abdominal pain that can occur with this medicine; however, food can reduce the amount of tacrolimus that is absorbed. This is especially true with fatty foods.
- Capsules should be taken consistently with or without food in order to avoid major swings in blood levels.
- Grapefruit juice increases blood levels of tacrolimus and should be avoided.
- The injection is only used for patients who cannot tolerate tacrolimus capsules.
Is tacrolimus safe to take if I'm pregnant or breastfeeding?
- Tacrolimus crosses the placenta, but there have been no adequate studies in pregnant women to assess the effects on the fetus. Among women who have received tacrolimus while pregnant, high potassium levels and kidney injury in newborns have been reported. Therefore, tacrolimus should be used during pregnancy only when it is clearly needed.
- Tacrolimus passes into breast milk. It is recommended that breastfeeding be discontinued while women are receiving oral tacrolimus.
What else should I know about tacrolimus?
What preparations of tacrolimus are available?
- Capsule: 0.5, 1, and 5 mg
- Tablets: 0.75, 1, 4 mg
- Injection: 5 mg/ml
How should I keep tacrolimus stored?
Tacrolimus should be stored at room temperature between 15 C and 30 C (59 F and 86 F).
Tacrolimus (Prograf, Astagraf XL, Envarsus XR) is a medication prescribed for the prevention of rejection of transplanted liver, heart, or kidneys. Side effects may include:
Multimedia: Slideshows, Images & Quizzes
Heart Disease: Causes of a Heart Attack
Learn about heart disease and heart attack symptoms and signs of a heart attack in men and women. Read about heart disease...
Heart Disease: Symptoms, Signs, and Causes
What is heart disease (coronary artery disease)? Learn about the causes of heart disease. Symptoms of heart disease include chest...
Kidney Disease Quiz: Test Your Medical IQ
Kidney disease is common. Take this kidney disease quiz to test your knowledge and learn the symptoms, causes and types of kidney...
Liver Disease Quiz: Fatty Liver Disease, Cirrhosis & Symptoms
What is liver disease? Take the Liver Disease Quiz and test your knowledge about this organ and its function....
Picture of Liver
Front View of the Liver. The liver is a large, meaty organ that sits on the right side of the belly. See a picture of the Liver...
Picture of Kidneys
The kidneys are a pair of organs located in the back of the abdomen. See a picture of the Kidneys and learn more about the health...
Related Disease Conditions
Kidney Failure (Symptoms, Signs, Stages, Causes, and Treatment)
Kidney failure can occur from an acute event or a chronic condition or disease. Prerenal kidney failure is caused by blood loss,...
Jock itch is an itchy red rash that appears in the groin area. The rash may be caused by a bacterial or fungal infection. People...
Liver disease can be cause by a variety of things including infection (hepatitis), diseases such as: gallstones, high...
Psoriasis is a long-term skin condition that may cause large plaques of red, raised skin, flakes of dry skin, and skin scales....
Eczema refers to skin inflammation. There are many different types of eczema that produce symptoms and signs that range from...
Liver (Anatomy and Function)
The liver is the largest gland and organ in the body. There are a variety of liver diseases caused by liver inflammation,...
Seborrheic dermatitis is a chronic skin condition. Symptoms and signs include a red, scaling rash on the scalp, face, ears, and...
Encephalopathy means brain disease, damage, or malfunction. Causes of encephalopathy are varied and numerous. The main symptom of...
Inflammatory Bowel Disease (Intestinal Problems of IBD)
The inflammatory bowel diseases (IBD) are Crohn's disease (CD) and ulcerative colitis (UC). The intestinal complications of...
Myasthenia gravis, a chronic autoimmune neuromuscular disease. Varying degrees of weakness of the voluntary muscles of the body...
Primary Sclerosing Cholangitis (PSC)
Primary sclerosing cholangitis or PSC is a disease of the liver. The cause of PSC is not known. Symptoms may include itching,...
Graft Versus Host Disease (GVHD)
Graft versus host disease (GVHD) is a condition that happens when immune cells from transplanted donor tissue attack the...
Treatment & Diagnosis
- Kidney Disease FAQs
- Liver Disease FAQs
- How To Reduce Your Medication Costs
- Pharmacy Visit, How To Get The Most Out of Your Visit
- Indications for Drugs: Approved vs. Non-approved
- Generic Drugs, Are They as Good as Brand-Names?
- Drugs: Buying Prescription Drugs Online Safely
- Drugs: The Most Common Medication Errors
- Medication Disposal - What to Do with Old or Unusable Medication
- Dangers of Mixing Medications
Medications & Supplements
Prevention & Wellness
- Study Suggests Causes for Lupus' Impact on Immune System
- New Kidney Transplant Drug Cuts Risk of Earlier Death: Study
- Mouse Study Hints at New 'Male Contraceptive'
- Drug Combo Helps Lupus-Related Kidney Condition
- New Technique Protects Tissue Transplant From Rejection: Study
- Many Lupus Patients Forgo Needed Medication, Study Finds
- HIV Drug May Prevent Bone Marrow Transplant Complication
Daily Health News
Drugs and Treatment Resources
Subscribe to MedicineNet's General Health Newsletter
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Top tacrolimus Related Articles
Eczema FactsEczema refers to skin inflammation. There are many different types of eczema that produce symptoms and signs that range from oozing blisters to crusty plaques of skin. Treatment varies depending upon the type of eczema the person has.
EncephalopathyEncephalopathy means brain disease, damage, or malfunction. Causes of encephalopathy are varied and numerous. The main symptom of encephalopathy is an altered mental state. Other symptoms include lethargy, dementia, seizures, tremors, and coma. Treatment of encephalopathy depends on the type of encephalopathy (anoxia, diabetic, Hashimoto's, hepatic, hyper - hypotensive, infectious, metabolic, infections, uremic, or Wernicke's) are examples of types of encephalopathy.
CAD SlideshowWhat is heart disease (coronary artery disease)? Learn about the causes of heart disease. Symptoms of heart disease include chest pain and shortness of breath. Explore heart disease diagnosis, treatment, and prevention.
Heart Disease SlideshowLearn about heart disease and heart attack symptoms and signs of a heart attack in men and women. Read about heart disease diagnostic tests, treatments, and prevention strategies.
Inflammatory Bowel Disease: Intestinal ProblemsThe inflammatory bowel diseases (IBD) are Crohn's disease (CD) and ulcerative colitis (UC). The intestinal complications of Crohn's disease and ulcerative colitis differ because of the characteristically dissimilar behaviors of the intestinal inflammation in these two diseases.
Jock ItchJock itch is an itchy red rash that appears in the groin area. The rash may be caused by a bacterial or fungal infection. People with diabetes and those who are obese are more susceptible to developing jock itch. Antifungal shampoos, creams, and pills may be needed to treat fungal jock itch. Bacterial jock itch may be treated with antibacterial soaps and topical and oral antibiotics.
Kidney Disease QuizKidney disease is common. Take this kidney disease quiz to test your knowledge and learn the symptoms, causes and types of kidney disease and what foods to eat and avoid!
Kidney failure can occur from an acute event or a chronic condition or disease. Prerenal kidney failure is caused by blood loss, dehydration, or medication. Some of the renal causes of kidney failure include sepsis, medications, rhabdomyolysis, multiple myeloma, and acute glomerulonephritis.
Post renal causes of kidney failure include bladder obstruction, prostate problems, tumors, or kidney stones.Treatment options included diet, medications, or dialysis.
Liver (Anatomy and Function)The liver is the largest gland and organ in the body. There are a variety of liver diseases caused by liver inflammation, scarring of the liver, infection of the liver, gallstones, cancer, toxins, genetic diseases, and blood flow problems. Symptoms of liver disease generally do not occur until the liver disease is advanced. Some symptoms of liver disease include jaundice, nausea and vomiting, easy bruising, bleeding excessively, fatigue, weakness, weight loss, shortness of breath, leg swelling, impotence, and confusion. Treatment of diseases of the liver depend upon the cause.
Liver DiseaseLiver disease can be cause by a variety of things including infection (hepatitis), diseases such as:
- high cholesterol or triglycerides,
- blood flow obstruction to the liver, and
- toxins (medications and chemicals).
- upper right abdominal pain, and
Liver Disease QuizWhat is liver disease? Take the Liver Disease Quiz and test your knowledge about this organ and its function.
Liver PictureFront View of the Liver. The liver is a large, meaty organ that sits on the right side of the belly. See a picture of the Liver and learn more about the health topic.
Liver TransplantA liver transplant may be needed when the liver functions inadequately. Patients on the waiting list for a liver transplant are given a priority score based on their creatinine, bilirubin, and INR. Complications of liver transplantation include rejection of the donor organ and infection.
PsoriasisPsoriasis is a long-term skin condition that may cause large plaques of red, raised skin, flakes of dry skin, and skin scales. There are several types of psoriasis, including psoriasis vulgaris, guttate psoriasis, inverse psoriasis, and pustular psoriasis. Symptoms vary depending on the type of psoriasis the patient has. Treatment of psoriasis may include creams, lotions, oral medications, injections and infusions of biologics, and light therapy. There is no cure for psoriasis.
Seborrheic DermatitisSeborrheic dermatitis is a chronic skin condition. Symptoms and signs include a red, scaling rash on the scalp, face, ears, and torso. Treatment often includes the use of a medicated shampoo and the application of a topical steroid lotion.