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What is Survanta, and how does it work?
Survanta (beractant) Intratracheal Suspension is a pulmonary surfactant made from animal lung extract and is used to treat or prevent respiratory distress syndrome in newborn infants.
What are the side effects of Survanta?
Common side effects of Survanta include:
- noisy breathing,
- feeding or bowel problems, or
- bleeding around the endotracheal tube.
Tell your child's doctor if the child has serious side effects of Survanta including:
What is the dosage for Survanta?
Important Administration Instructions
- For intratracheal administration (given via needle or catheter inserted into the throat) only.
- Survanta should be administered by or under the supervision of clinicians experienced in intubation, ventilator management, and general care of premature infants. The administration of Survanta is facilitated if one person administers the dose while another person positions and monitors the infant.
- Before administering Survanta, assure proper placement and patency of the endotracheal tube. At the discretion of the clinician, the endotracheal tube may be suctioned before administering Survanta. The infant should be allowed to stabilize before proceeding with dosing.
- Administer Survanta intratracheally by instillation through a 5 French end-hole catheter.
- Each dose of Survanta is 100 mg of phospholipids/kg birth weight (4 mL/kg).
- In the prevention strategy, in premature infants with evidence of surfactant deficiency, give the first dose of Survanta as soon as possible, preferably within 15 minutes of birth.
- To treat infants with RDS confirmed by radiographic and clinical findings, give the first dose of Survanta as soon as possible, preferably by 8 hours of age.
- Four doses of Survanta can be administered in the first 48 hours of life.
- Doses should be given no more frequently than every 6 hours.
- The need for additional doses of Survanta is determined by evidence of continuing respiratory distress. Radiographic confirmation of RDS should be obtained before administering additional doses to those who received a prevention dose.
Is Survanta safe to use while pregnant or breastfeeding?
Survanta (beractant) Intratracheal Suspension is a pulmonary surfactant made from animal lung extract and is used to treat or prevent respiratory distress syndrome in newborn infants. Common side effects of Survanta include noisy breathing, feeding or bowel problems, or bleeding around the endotracheal tube.
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Related Disease Conditions
Sudden Infant Death Syndrome (SIDS)
The cause of sudden infant death syndrome (SIDS) is unknown. The risk of SIDS peaks in infants 2-4 months of age. SIDS is more common among male infants, particularly African American and Native American infants, during the winter months. Putting the baby to sleep on his/her back, avoiding fluffy, loose bedding, using a firm mattress, and avoiding co-sleeping may help to prevent SIDS.
Jaundice (Newborn, Kernicterus)
Jaundice in infants occur when the baby's liver may not be developed enough to efficiently rid the body of bilirubin. Symptoms of jaundice include yellowish colored eyes, and yellowing of the skin. Some babies are more at risk to develop jaundice. Kernicterus is a type of brain damage that occurs when a baby has jaundice and is not treated. Treatment of infant jaundice is generally with phototherapy so that kernicterus should not develop.
ARDS (Acute Respiratory Distress Syndrome)
Acute respiratory distress syndrome (ARDS) is a lung condition in which trauma to the lungs leads to inflammation of the lungs, accumulation of fluid in the alveolar air sacs, low blood oxygen, and respiratory distress. ARDS can be life-threatening. Signs and symptoms of are shortness of breath and low levels of oxygen in the blood, which can cause your organs to fail. Causes of ARDS include: Pneumonia Aspiration into the lungs Severe blow to the chest Sepsis Severe injury with shock Drug overdose Inflamed pancreas Other lung conditions and infections Burns Sepsis Near drowning Fractures There have been genetic factors linked to ARDS. Treatment for includes supplemental oxygen, and/or medication. According to some studies, survival rates for ARDS depend upon the cause associated with it, but can vary from 48% to 68%.REFERENCES: Harman, EM, MD. "Acute Respiratory Distress Syndrome Clinical Presentation." Medscape. Updated: Aug 11, 2016. Harman, EM, MD. "Acute Respiratory Distress Syndrome." Medscape. Updated: Aug 11, 2016. PubMed Health. "ARDS." Updated: Jun 11, 2014. Reynolds, HN. et al. Acute respiratory distress syndrome: estimated incidence and mortality rate in a 5 million-person population base. Crit Care. 1998; 2(1): 29–34. Published online 1998 Mar 12. doi: 10.1186/cc121
Urine Blockage in Newborns
There are many syndromes and defects that may cause urine blockage in newborns. Defects in the urinary tract that may cause urine blockage include vesicoureteral reflux, ureteropelvic junction obstruction, bladder outlet obstruction, posterior urethral valves, nerve disease, and ureterocele. Syndromes that may cause urinary blockage include congenital heart defects, esophageal atresia, and prune belly syndrome. Treatment for urine blockage in newborns depends on the cause of the blockage.
Newborn Jaundice (Neonatal Jaundice)
Jaundice in newborns and babies (neonatal jaundice) usually occurs because of a normal increase in red blood cell breakdown and the fact that their immature livers are not efficient at removing bilirubin from the bloodstream. Symptoms of jaundice are fever, poor feeding, and looking ill. Newborn jaundice is very common and is caused because the newborns liver isn’t mature enough to remove bilirubin from the blood. Treatment of jaundice in newborns include phototherapy, tanning booths, and other treatments.
How Long Can a Newborn Go Without Peeing?
A newborn baby usually passes urine for the first time within 12 to 24 hours after birth. Not peeing in the first 24 hours points to some urinary tract problem. As the mother and her baby need to stay in the hospital for 24 to 48 hours after a normal delivery, it becomes easy for the doctors to diagnose the condition early.
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