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- Suprax (cefixime) vs. cefuroxime: What's the difference?
- What are Suprax and cefuroxime?
- What are the side effects of Suprax and cefuroxime?
- What is the dosage of Suprax vs. cefuroxime?
- What drugs interact with Suprax and cefuroxime?
- Are Suprax and cefuroxime safe to use while pregnant or breastfeeding?
Suprax (cefixime) vs. cefuroxime: What's the difference?
- Suprax (cefixime) and cefuroxime are cephalosporin antibiotics used to treat infections of the middle ear (otitis media), tonsillitis, throat infections (pharyngitis), laryngitis, bronchitis, pneumonia, urinary tract infections (UTIs), gonorrhea, and acute bacterial bronchitis in patients with chronic obstructive pulmonary disease (COPD).
- Cefuroxime is also used to treat early Lyme disease.
- Suprax is a brand name for cefixime.
- Brand names for cefuroxime include Ceftin and Zinacef.
- Side effects of Suprax and cefuroxime that are similar include diarrhea, nausea, vomiting, abdominal pain, skin rash, vaginitis, and headaches.
- Side effects of Suprax that are different from cefuroxime include fever, joint pain, abnormal liver tests, itching, and dizziness.
- Side effects of cefuroxime that are different from Suprax include hives and mouth ulcers.
What are Suprax and cefuroxime?
Suprax is a cephalosporin antibiotic used to treat infections of the middle ear (otitis media), tonsillitis, throat infections (pharyngitis), laryngitis, bronchitis, pneumonia, urinary tract infections (UTIs), gonorrhea, and acute bacterial bronchitis in patients with chronic obstructive pulmonary disease (COPD). Other cephalosporins include cephalexin (Keflex), cefaclor (Ceclor), cefuroxime (Zinacef), cefpodoxime (Vantin), cefprozil (Cefzil), and injectable forms. Like other cephalosporins, Suprax stops bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together; most bacteria cannot survive without a cell wall. Suprax is active against bacteria such as Staphylococcus aureus, Streptococcus pyogenes (causes strep throat), Streptococcus pneumoniae, Hemophilus influenzae, E. coli, Klebsiella, Moraxella catarrhalis, Proteus mirabilis, Salmonella, Shigella, and Neisseria gonorrhoeae.
Cefuroxime is a cephalosporin antibiotic used to treat infections of the middle ear, sinuses, skin, tonsils, and throat, and to treat laryngitis, bronchitis, pneumonia, urinary tract infections, gonorrhea, COPD, and early Lyme disease. Cephalosporins stop or slow the growth of bacterial cells by preventing bacteria from forming the cell wall that surrounds each cell. The cell wall protects bacteria from the external environment and keeps the contents of the cell together. Without a cell wall, bacteria are not able to survive. Cefuroxime is effective against a wide variety of bacteria, such as Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, E. coli, N. gonorrhea, and many others.
What are the side effects of Suprax and cefuroxime?
Common side effects of Suprax include:
Other side effects include:
Cefuroxime is generally well tolerated, and side effects are usually transient. Commonly reported side effects are:
Other important side effects include:
Since cefuroxime is chemically related to penicillin, patients allergic to penicillin may develop an allergic reaction (sometimes even anaphylaxis) to cefuroxime. Cefuroxime like other antibiotics can alter the colon's normal bacteria, leading to overgrowth of a bacterium called Clostridium difficile. Overgrowth of this bacterium leads to the release of toxins that contribute to the development of Clostridium difficile-associated diarrhea, which may range in severity from mild diarrhea to fatal pseudomembranous colitis.
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What is the dosage of Suprax vs. cefuroxime?
The recommended adult dose for otitis media, tonsillitis, pharyngitis, and urinary tract infections is 400 mg once daily or divided and given as 200 mg every 12 hours. Pediatric patients (6 months and older) have a recommended dose of 8 mg/kg/day once daily or in two doses of 4/mg/kg every 12 hours.
Typical adult oral doses are 250 or 500 mg twice daily for 7-20 days depending on the type and severity of the infection. A single 1000 mg dose may be used for uncomplicated gonorrhea. The tablets and suspension are not interchangeable.
What drugs interact with Suprax and cefuroxime?
Probenecid (Benemid) may increase the blood concentration of Suprax by decreasing removal of Suprax by the kidney. This interaction sometimes is used to enhance the effect of cephalosporins.
Combining Suprax with aminoglycosides -- for example, tobramycin (Tobradex) -- produces additive bacterial killing effects but also may increase the risk of harmful effects to the kidney.
Suprax may cause a false positive urine ketone test.
Probenecid increases the concentration of cefuroxime in the blood. Drugs that reduce acidity in the stomach (for example, antacids, H2-blockers, proton pump inhibitors) may reduce absorption of cefuroxime.
Are Suprax and cefuroxime safe to use while pregnant or breastfeeding?
Cephalosporins are usually considered safe for use during pregnancy.
Cefuroxime is excreted in breast milk and may cause adverse effects in the infant. Cefuroxime is approved for pediatric patients 3 months and older.
Suprax and cefuroxime are cephalosporin antibiotics used to treat infections of the middle ear (otitis media), tonsillitis, throat infections (pharyngitis), laryngitis, bronchitis, pneumonia, urinary tract infections (UTIs), gonorrhea, and acute bacterial bronchitis in patients with chronic obstructive pulmonary disease (COPD). Cefuroxime is also used to treat early Lyme disease.
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Related Disease Conditions
Staph Infection (Staphylococcus Aureus)
Staphylococcus or staph is a group of bacteria that can cause a multitude of diseases. Staph infections can cause illness directly by infection or indirectly by the toxins they produce. Symptoms and signs of a staph infection include redness, swelling, pain, and drainage of pus. Minor skin infections are treated with an antibiotic ointment, while more serious infections are treated with intravenous antibiotics.
Pneumonia (Symptoms, Causes, Types, Treatment, and Recovery)
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.
Upper Respiratory Tract Infection (URTI)
An upper respiratory infection is a contagious infection of the structures of the upper respiratory tract, which includes the sinuses, nasal passages, pharynx, and larynx. Common causes of an upper respiratory infection include bacteria and viruses such as rhinoviruses, group A streptococci, influenza, respiratory syncytial, whooping cough, diphtheria, and Epstein-Barr. Examples of symptoms of upper respiratory infection include sneezing, sore throat, cough, fever, and nasal congestion. Treatment of upper respiratory infections are based upon the cause. Generally, viral infections are treated symptomatically with over-the-counter (OTC) medication and home remedies.
Middle Ear Infection (Otitis Media)
Middle ear infection (otitis media) is inflammation of the middle ear. There are two forms of this type of ear infection, acute and chronic. Acute otitis media is generally short in duration, and chronic otitis media generally lasts several weeks. Babies, toddlers, and children with a middle ear infection may be irritable, pull and tug at their ears, and experience numerous other symptoms and signs. Treatment depends upon the type of ear infection.
Urinary Tract Infection (UTI)
A urinary tract infection (UTI) is an infection of the bladder, kidneys, ureters, or urethra. E. coli, a type of bacteria that lives in the bowel and near the anus, causes most UTIs. UTI symptoms include pain, abdominal pain, mild fever, urinary urgency and frequency. Treatment involves a course of antibiotics.
Tonsillitis is a contagious infection with symptoms of bad breath, snoring, congestion, headache, hoarseness, laryngitis, and coughing up blood. Tonsillitis can be caused acute infection of the tonsils, and several types of bacteria or viruses (for example, strep throat or mononucleosis). There are two types of tonsillitis, acute and chronic. Acute tonsillitis lasts from one to two weeks while chronic tonsillitis can last from months to years. Treatment of tonsillitis and adenoids include antibiotics, over-the-counter medications, and home remedies to relieve pain and inflammation, for example, salt water gargle, slippery elm throat lozenges, sipping warm beverages and eating frozen foods (ice cream, popsicles), serrapeptase, papain, and andrographism Some people with chronic tonsillitis may need surgery (tonsillectomy or adenoidectomy).
Sore throat (throat pain) usually is described as pain or discomfort in the throat area. A sore throat may be caused by bacterial infections, viral infections, toxins, irritants, trauma, or injury to the throat area. Common symptoms of a sore throat include a fever, cough, runny nose, hoarseness, earaches, sneezing, and body aches. Home remedies for a sore throat include warm soothing liquids and throat lozenges. OTC remedies for a sore throat include OTC pain relievers such as ibuprofen or acetaminophen. Antibiotics may be necessary for some cases of sore throat.
Laryngitis is an inflammation of the voice box (vocal cords). The most common cause of acute laryngitis is infection, which inflames the vocal cords. Symptoms may vary from degree of laryngitis and age of the person (laryngitis in infants and children is more commonly caused by croup). Common symptoms include a "barky" cough, a hoarse cough, fever, cold, runny nose, dry cough, and loss of voice. Chronic laryngitis generally lasts more than three weeks. Causes other than infection include smoking, excess coughing, GERD, and more. Treatment depends on the cause of laryngitis.
E. coli (0157:H7) Infection
There are many types of E. coli (Escherichia coli). E. coli can cause urinary tract and bladder infections, or lead to sepsis. E coli O157:H7 (EHEC) causes bloody diarrhea and colitis. Complications of E. coli infection include hemorrhagic diarrhea, hemolytic-uremic syndrome, and thrombotic thrombocytopenic purpura. Symptoms include severe abdominal pain and bloody diarrhea. E coli O157:H7 commonly is due to eating raw or undercooked hamburger or raw milk or dairy products.
Gonorrhea In Women
Gonorrhea is a bacterial infection transmitted during sexual contact. In women, symptoms include a yellow vaginal discharge, burning or frequent urination, and redness, swelling, burning and itching of the vaginal area. Gonorrhea can be treated with injectable (penicillin) or oral medications.
COPD (Chronic Obstructive Pulmonary Disease)
COPD or chronic obstructive pulmonary disease is a lung condition caused by smoking tobacco, exposure to secondhand smoke, and/or air pollutants. Conditions that accompany COPD include chronic bronchitis, chronic cough, and emphysema. Symptoms of COPD include shortness of breath, wheezing, and chronic cough. Treatment of COPD includes GOLD guidelines, smoking cessation, medications, and surgery. The life expectancy of a person with COPD depends on the stage of the disease.
Group A streptococcal infections are caused by group A streptococcus, a bacteria that causes a variety of health problems, including strep throat, impetigo, cellulitis, erysipelas, and scarlet fever. There are more than 10 million group A strep infections each year.
Bronchitis (Acute) Contagoius Symptoms, Causes, Treatment, and Recovery Time
Bronchitis is inflammation of the airways in the lung. Acute bronchitis is is short in duration (10 to 20 days) in comparison with chronic bronchitis, which lasts for months to years. Causes of acute bronchitis include viruses and bacteria, which means it can be contagious. Acute bronchitis caused by environmental factors such as pollution or cigarette smoke is not contagious. Common symptoms for acute bronchitis include nasal congestion, cough, headache, sore throat, muscle aches, and fatigue. Acute bronchitis in children also my include runny nose, fever, and chest pain. Treatment for acute bronchitis are OTC pain relievers, cough suppressants (although not recommended in children), and rest. Infrequently antibiotics may be prescribed to treat acute bronchitis.
Lyme disease is a bacterial illness, which is spread by ticks when they bite the skin. Initially the disease affects the skin causing a reddish rash associated with flu-like symptoms. It takes weeks to months after the initial redness of the skin for its effects to spread throughout the body. Lyme disease can be treated with antibiotics. Lyme disease can be prevented by using tick avoidance techniques.
Group A Streptococcal Infections
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Chronic Bronchitis (Symptoms, Causes, Treatment, Remedies)
Chronic bronchitis is a cough that occurs daily with production of sputum that lasts for at least three months, two years in a row. Causes of chronic bronchitis include cigarette smoking, inhaled irritants, and underlying disease processes (such as asthma, or congestive heart failure). Symptoms include cough, shortness of breath, and wheezing. Treatments include bronchodilators and steroids. Complications of chronic bronchitis include COPD and emphysema.
Shigellosis is a disease caused by the Shigella bacteria. Bloody diarrhea, stomach cramps, and fever are common symptoms. Mild infections usually resolve on their own. Antibiotics are used to treat more severe cases.
Treatment & Diagnosis
- Swollen Tonsils
- Urinary Tract Infection (UTI)
- Upper Respiratory Infection
- Middle Ear Infection (Otitis Media)
- Sore Throat (Pharyngitis)
- Lyme Disease
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- Doctor: Getting the Most from Your Doctor's Appointment
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- Lyme Disease FAQs
- Pneumonia FAQs
- Strep Streptococcal Throat Infection FAQs
- Ear Infection FAQs
- Bronchitis FAQs
- How Do You Get Staph Infection?
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- How Do You Get an Ear Infection?
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Medications & Supplements
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