Soybean Oil

What other names is Soybean Oil known by?

Aceite de Soja, Dolichos soja, Glycine gracilis, Glycine hispida, Glycine max, Glycine soja, Huile de Germes de Soja, Huile de Germes de Soya, Huile de Soja, Huile de Soya, Intralipid, Intralipide, Legume, Légumineuse, Phaseolus max, Soja hispida, Soja max, Soy Bean Oil, Soy Oil, Soya Oil, Soyca, Travmulsion.

What is Soybean Oil?

Soybean oil is produced from the seeds of the soybean plant.

Plant sterols, chemicals derived from soybean oil, are used to lower total cholesterol and “bad” low-density lipoprotein (LDL) cholesterol. Specially processed soybean oil is used to treat osteoarthritis.

Some people apply soybean oil directly to the skin to repel mosquitoes and other insects.

Soybean oil is also used as a nutritional supplement in intravenous feedings.

Effective for...

  • Use as a nutritional supplement in intravenous feedings.

Likely Effective for...

  • Preventing mosquito bites when applied to the skin. Soybean oil is an ingredient in some commercial mosquito repellents. It seems to work about as well as some other mosquito repellents including some products that contain a small amount of DEET.

Possibly Effective for...

  • Lowering cholesterol levels in people with high cholesterol. Soybean oil plant sterols used in margarine seem to help lower total cholesterol and “bad” LDL cholesterol without affecting “good” HDL. The FDA has allowed the makers of the products Take Control and Benecol to include this claim on their labels.
  • Osteoarthritis, when a specific processed part of the oil (unsaponifiable fractions) is used in combination with avocado oil. This combination seems to significantly improve pain and overall disability. It appears to work better for osteoarthritis of the hip than the knee.

QUESTION

What joints are most often affected by osteoarthritis? See Answer

Insufficient Evidence to Rate Effectiveness for...

How does Soybean Oil work?

Soybean oil works to lower cholesterol levels by decreasing cholesterol absorption in the gut. Specific processed parts of soybean oil called unsaponifiables may have a beneficial effect on joints.

Are there safety concerns?

Soybean oil is safe for most adults when taken by mouth in amounts normally found in food and when applied to the skin as an insect repellent in recommended amounts. Pharmaceutical quality soybean oil is also safe when used as a nutritional supplement in intravenous feedings. The processed soybean oil (unsaponifiable fractions of soybean oil) has been used safely in research studies for up to 6 months.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Soybean oil is safe for pregnant and breast-feeding women when used as part of the diet. But the safety of soybean oil during pregnancy and breast-feeding is not known when used in amounts greater than those commonly found in foods.

Peanut or soybean allergy: People who are allergic to peanuts, soybeans and other plants that are members of the Fabaceae/Leguminosea family might also be allergic to soybean oil.

Dosing considerations for Soybean Oil.

The following doses have been studied in scientific research:

BY MOUTH:

  • In the form of an enriched margarine, such as Take Control, a serving size is one tablespoon, or 14 grams.
  • For osteoarthritis: 300 mg soybean oil daily along with avocado oil.
APPLIED TO THE SKIN:
  • For preventing mosquito bites: 2% soybean oil products have been used. Directions on one commercial product (Bite Blocker) suggest reapplying every 2 hours.

CONTINUE SCROLLING FOR RELATED SLIDESHOW

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

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Reviewed on 9/17/2019
References

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Bardare M, Magnolfi C, Zani G. Soy sensitivity: personal observation on 71 children with food intolerance. Allerg Immunol (Paris) 1988;20:63-6.

Drugs in Pregnancy and Lactation. 4th ed. Baltimore, MD: Williams & Wilkins, 1994.

Eigenmann PA, Burks AW, Bannon GA, et al. Identification of unique peanut and soy allergens in sera adsorbed with cross-reacting antibodies. J Allergy Clin Immunol 1996;98:969-78. View abstract.

Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182

FDA. Center for Science in the Public Interest. A Food Labeling Guide. Available at: http://www.cfsan.fda.gov/~dms/flg-6c.html

Fradin MS, Day JF. Comparative efficacy of insect repellents against mosquito bites. N Engl J Med 2002;347:13-8. View abstract.

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Henrotin YE, Sanchez C, Deberg MA, et al. Avocado/soybean unsaponifiables increase aggrecan synthesis and reduce catabolic and proinflammatory mediator production by human osteoarthritic chondrocytes. J Rheumatol 2003;30:1825-34. View abstract.

Lequesne M, Maheu E, Cadet C, Dreiser RL. Structural effect of avocado/soybean unsaponifiables on joint space loss in osteoarthritis of the hip. Arthritis Rheum 2002;47:50-8.. View abstract.

Lichtenstein AH, Ausman LM, Jalbert SM, et al. Effects of different forms of dietary hydrogenated fats on serum lipoprotein cholesterol levels. N Engl J Med 1999;340:1933-40. View abstract.

Maheu E, Mazieres B, Valat JP, et al. Symptomatic efficacy of avocado/soybean unsaponifiables in the treatment of osteoarthritis of the knee and hip: a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial with a six-month treatment period and a two-month followup demonstrating a persistent effect. Arthritis Rheum 1998;41:81-91. View abstract.

Public Health Agency of Canada. Canadian Recommendations for the Prevention and Treatment of Malaria Among International Travellers. Available at: http://www.phac-aspc.gc.ca/publicat/ccdr-rmtc/04vol30/30s1/page2_e.html (Accessed 24 May 2005).

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Weststrate JA, Meijer GW. Plant sterol-enriched margarines and reduction of plasma total- and LDL-cholesterol concentrations in normocholesterolaemic and mildly hypercholesterolaemic subjects. Eur J Clin Nutr 1998;52:334-43. View abstract.