Sjogren's Syndrome: Symptoms & Signs

Medically Reviewed on 9/10/2019

With Sjögren's syndrome, the immune response attacks and damages glands that produce secretions that pass to the outside of the body. Therefore, symptoms like dry eyes and a dry mouth are common. The exact reason that the autoimmune reaction occurs is not clear. People who have Sjögren's syndrome may also have a rheumatic disease such as rheumatoid arthritis or lupus.

Signs and symptoms of Sjögren's syndrome can include abnormality of taste, loss of taste, hoarseness, impaired voice, difficulty swallowing, throat dryness, dry cough, and dry eyes. Other nonspecific associated symptoms include fatigue, joint stiffness, joint swelling, diarrhea, vaginal dryness, swollen salivary glands, and abdominal pain.

Cause of Sjögren's syndrome

An autoimmune reaction in the body causes Sjögren's syndrome.

Other sjogren's syndrome symptoms and signs


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Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.