Simethicone is an anti-gas (anti-flatulence) medication. It acts in the stomach and intestines to change the surface tension of gas bubbles, enabling their breakdown and the formation of larger bubbles. In this way it is believed that gas can be eliminated more easily by belching or passing flatus. Simethicone was approved by the FDA in 1952.

GENERIC AVAILABLE: Yes

No

Simethicone relieves abdominal pain due to excessive gas in the digestive tract. It also is given to patients undergoing upper abdominal ultrasound imaging.

Common side effects may include:

• diarrhea,
• nausea,
• vomiting, and
• headache.

The recommended dose for relieving gas is 40-125 mg 4 times daily after meals and at bedtime. The drops can be mixed with water, infant formula or other liquids for use in small children.

: There are no known drug interactions with simethicone.

Safety during pregnancy has not been adequately evaluated. Simethicone is generally considered safe during pregnancy because it does not cross the placenta.

Simethicone is considered safe during lactation because it is not absorbed into the body and infants are often treated with simethicone.

What preparations of simethicone are available?

Liquid drops: 40 mg per 0.6 ml. Chewable tablets: 40, 80 and 125 mg. Capsules: 125 and 180 mg.

How should I keep simethicone stored?

Preparations should be stored at room temperature, 15 C - 30 C (59 F - 86 F).