- What is simeprevir, and how does it work (mechanism of action)?
- What brand names are available for simeprevir?
- Is simeprevir available as a generic drug?
- Do I need a prescription for simeprevir?
- What are the side effects of simeprevir?
- What is the dosage for simeprevir?
- Is simeprevir safe to take if I'm pregnant or breastfeeding?
- What else should I know about simeprevir?
What is simeprevir, and how does it work (mechanism of action)?
Simeprevir is an oral, direct-acting an-tiviral agent used for treating infections with the hepatitis C virus (HCV). Boceprevir (Victrelis), telaprevir (Incivek), and sofosbuvir (Sovaldi) are other direct-acting drugs for treating HCV. Simeprevir blocks the effect of pro-teases which are enzymes that HCV needs for making new viruses, leading to reduced numbers of HCV in the body. Simeprevir is effective for treating people infected with HCV genotype 1, including those with liver disease. The FDA approved simeprevir in November 2013.
What is the dosage for simeprevir?
The recommended dose of simeprevir is one 150 mg capsule once daily with food for 12 weeks in combination with peginter-feron and ribavarin. It should be followed by 12 or 36 additional weeks of peginterferon and ribavirin depending on prior response. It can also be combined with sofosbuvir (Sovaldi) for 12 weeks.
Is simeprevir safe to take if I'm pregnant or breastfeeding?
It is not known if simeprevir is secreted into breast milk.
What else should I know about simeprevir?
What preparations of simeprevir are available?
Capsules: 150 mg
How should I keep simeprevir stored?
Capsules should be stored at room temperature below 30 C (86 F).
Simeprevir (Olysio) is an oral, direct-acting antiviral agent prescribed for treating infections with HCV (hepatitis C virus). Simeprevir is used in combination with ribavirin (Rebetol, Copegus) and peginterferon to treat hepatitis C infections. Drug interactions, warnings and precautions, side effects, and dosage information should be reviewed prior to taking this medication.
Multimedia: Slideshows, Images & Quizzes
Hepatitis C Quiz: What is Hepatitis C?
How many Americans have hepatitis C? Take this quiz to learn the facts about this chronic disease....
Hepatitis C, Hep B, Hep A: Symptoms, Causes, Treatment
What is hepatitis? Hepatitis A, B, and C spread in different ways, causing mild to serious effects on the liver. Learn about...
Hepatitis: How Do You Get Hepatitis A, B, and C?
Hepatitis C virus and hepatitis B can make an infected person very sick and they are risk factors for liver cancer, liver...
Hepatitis C (Hep C) Symptoms and Treatment
What is Hepatitis C (Hep C, HVC)? Learn about hepatitis c symptoms, how you get hepatitis c, contagiousness, and hepatitis C...
Related Disease Conditions
Hepatitis (Viral Hepatitis, A, B, C, D, E, G)
Hepatitis is most often viral, due to infection with one of the hepatitis viruses (A, B, C, D, E, F (not confirmed), and G) or...
Hepatitis C (HCV, Hep C)
Hepatitis C is an inflammation of the liver due to the hepatitis C virus (HCV), which is usually spread by blood transfusion,...
Is Hepatitis C Contagious?
Hepatitis C or hep C causes acute and chronic liver disease. Hep C is a form of liver disease with symptoms like: fatigue,...
Hepatitis C Cure (Symptoms, Transmission, Treatments, and Cost)
Hepatitis is inflammation of the liver. There are a variety of toxins, diseases, illicit drugs, medications, bacterial and viral...
Treatment & Diagnosis
Medications & Supplements
Prevention & Wellness
Health Solutions From Our Sponsors
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
REFERENCE: FDA.gov prescribing information. simeprevir.