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- Psoriasis Quiz: Test Your Medical IQ
- Moderate to Severe Forms of Psoriasis Slideshow
What is Topicort (desoximetasone)?
Topicort (desoximetasone) is a corticosteroid used on the skin (topically) to treat adults with moderate to severe plaque psoriasis. Topicort is also used to treat other skin conditions responsive to corticosteroids.
The naturally occurring corticosteroid is cortisol or hydrocortisone produced by the adrenal gland. Corticosteroids have potent anti-inflammatory actions and also suppress the immune response.
Common side effects of Topicort include:
- application site burning,
- irritation, and
Other side effects of Topicort include:
- rash around the mouth,
- allergic contact dermatitis,
- abnormal hair growth,
- loss of skin pigmentation (hypopigmentation),
- stretch marks, and
- “sweat rash.”
Serious side effects of Topicort include:
- softening and breakdown of skin,
- secondary infection, and
- skin atrophy.
Prolonged use (greater than two weeks) of high doses of Topicort can depress the ability of the body's adrenal glands to produce corticosteroids. Abruptly stopping Topicort in these individuals can cause symptoms of corticosteroid insufficiency, along with nausea, vomiting, and shock.
Topicort has not been adequately evaluated in pregnant women. Pregnant patients should not use corticosteroids extensively, in large amounts, or for prolonged periods of time.
What are the important side effects of Topicort (desoximetasone)?
Common side effects of Topicort include:
Other side effects include:
- Perioral dermatitis
- Allergic contact dermatitis
- Abnormal hair growth
- Acneiform eruptions
Other less common side effects include:
Possible serious side effects include:
- Maceration of the skin
- Secondary infection
- Skin atrophy
Prolonged use (greater than two weeks) of high doses of Topicort can depress the ability of the body's adrenal glands to produce corticosteroids. Abruptly stopping Topicort in these individuals can cause symptoms of corticosteroid insufficiency, along with:
Topicort (desoximetasone) side effects list for healthcare professionals
The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence:
- acneiform eruptions,
- perioral dermatitis,
- allergic contact dermatitis,
- maceration of the skin,
- secondary infection,
- skin atrophy,
- striae, and
In controlled clinical studies the incidence of adverse reactions was low (0.2%) for Topicort (desoximetasone) Ointment USP, 0.05% and included mild burning sensation at the site of application.
Multimedia: Slideshows, Images & Quizzes
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Picture of Psoriasis 1
A reddish, scaly rash often located over the surfaces of the elbows, knees, scalp, and around or in the ears, navel, genitals or...
Picture of Psoriasis 2
More than one-quarter of all individuals with psoriasis develop their disease during childhood or adolescence. See a picture of...
Picture of Psoriasis 3
This figure shows the erythema, scaling, and thickening of portions of the thumb and soles that are very common in both children...
Picture of Psoriasis Vulgaris Soles
Well-demarcated, erythematous plaques with thick, yellowish lamellar scale and desquamation on sites of pressure arising on the...
Picture of Psoriasis Vulgaris Palms
Silvery-white scaly plaque, sharply demarcated, of irregular configuration. See a picture of Psoriasis Vulgaris Palms and learn...
Picture of Guttate Psoriasis
Guttate psoriasis is a type of psoriasis that looks like small, salmon-pink drops on the skin. See a picture of Guttate Psoriasis...
Picture of Inverse Psoriasis
Inverse psoriasis consists of bright red, smooth (not scaly) patches found in the folds of the skin. See a picture of Inverse...
Picture of Pustular Psoriasis
Pustular psoriasis is an uncommon form of psoriasis. See a picture of Pustular Psoriasis and learn more about the health topic.
Picture of Erythrodermic Psoriasis
This is the least common type of psoriasis and can be quite serious. See a picture of Erythrodermic Psoriasis and learn more...
Picture of Psoriasis of the Scalp
The scalp may have fine, dry, scaly skin or have heavily crusted plaque areas. See a picture of Psoriasis of the Scalp and learn...
Picture of Psoriasis Vulgaris
Pinpoint pits and distal onycholysis (so-called "oil-spot" discoloration) are seen in the fingernails of a child with psoriasis....
Picture of Psoriasis Vulgaris Erythematous
Well-delineated erythematous plaque located on the elbow of a child with psoriasis.See a picture of Psoriasis Vulgaris...
Picture of Psoriasis Vulgaris Plaque
Well-delineated erythematous plaque with a silvery-white scale characteristic of psoriasis. See a picture of Psoriasis Vulgaris...
Related Disease Conditions
Psoriasis is a long-term skin condition that may cause large plaques of red, raised skin, flakes of dry skin, and skin scales. There are several types of psoriasis, including psoriasis vulgaris, guttate psoriasis, inverse psoriasis, and pustular psoriasis. Symptoms vary depending on the type of psoriasis the patient has. Treatment of psoriasis may include creams, lotions, oral medications, injections and infusions of biologics, and light therapy. There is no cure for psoriasis.
Scalp Psoriasis (Psoriasis of the Scalp)
Scalp psoriasis causes red, raised, scaly patches that may extend from the scalp to the forehead and the back of the neck and ears. Symptoms and signs include itching, hair loss, flaking, silvery scales, and red plaques. Treatment includes topical medicated shampoos, creams, gels, oils, ointments, and soaps, medications, and light therapy.
What Is the Best Treatment for Psoriasis?
Psoriasis is an incurable chronic autoimmune disorder of the skin that causes patches of thick, flaky, scaly skin, mostly around the scalp, knees, and elbows, though any skin surface may be involved. Some people experience only small patches while others have red, inflamed skin and think scaly patches all over the body. The exact cause of psoriasis is not clear, but it isn’t contagious.
Is Psoriasis Contagious?
Psoriasis is an incurable skin disease that causes reddish patches of skin topped with a thick layer of dry silvery scales. Psoriasis cannot spread and is not contagious.
Treatment & Diagnosis
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Medications & Supplements
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration.