Does Sudafed (pseudoephedrine) cause side effects?
Vasoconstriction reduces nasal congestion by preventing fluid from draining from blood vessels into nasal passages. Sudafed also directly stimulates beta-adrenergic receptors and causes relaxation of bronchioles, as well as increased heart rate and contractility. Sudafed is available over-the-counter (OTC) and as a generic.
Common side effects of Sudafed include
Serious side effects of Sudafed include
What are the important side effects of Sudafed (pseudoephedrine)?
Common side effects of pseudoephedrine include:
- Possible serious side effects of pseudoephedrine include:
- High blood pressure
- Heart attack
- Abnormal heartbeats
- Ischemic colitis
It should be used with caution in people with
Sudafed (pseudoephedrine) side effects list for healthcare professionals
Common side effects of Sudafed include
What drugs interact with Sudafed (pseudoephedrine)?
Sudafed drug interactions include
- monoamine oxidase inhibitors or MAOIs (for example, isocarboxazid [Marplan]),
- serotonin and norepinephrine reuptake inhibitors (for example, venlafaxine [Effexor]),
- bronchodilators (for example, albuterol [Proventil]),
- blood pressure medications (such as beta blockers [Atenolol]) and
- calcium channel blockers [for example, verapamil]).
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Related Disease Conditions
Cold Sores (Nongenital Herpes Simplex Infections)
Herpes simplex infections are common and when they appear around the mouth and lips, people often refer to them as "cold sores" and "fever blisters." Canker sores are different than cold sores. Air droplets can spread the virus, as can direct contact with the fluid from the blisters. Cold sore treatment include over-the-counter medication, as well as prescription medications.
The common cold (viral upper respiratory tract infection) is a contagious illness that may be caused by various viruses. Symptoms include a stuffy nose, headache, cough, sore throat, and maybe a fever. Antibiotics have no effect upon the common cold, and there is no evidence that zinc and vitamin C are effective treatments.
Pimple vs. Cold Sore
Pimples are areas of skin inflammation with pus in the center. Cold sores are fluid-filled blisters. Pimples are caused by bacterial overgrowth and inflammation. Cold sores are caused by infection with herpes simplex viruses (HSV-1 and HSV-2). Benzoyl peroxide and sometimes antibiotics treat acne. Antiviral medications accelerate the healing process of oral herpes.
Cold and Cough Medicine for Infants and Children
The safety of giving infants and children over-the-counter (OTC) cold and cough medicine is important for caregivers to understand. While there is no "gold standard" recommendation for giving infants and children OTC cold and cough medicine for fever, aches, cough, and runny nose, a few standards have been recommended. The American Academy of Pediatrics recommends that OTC cold and cough medicine only be used in children age four years and older. The American College of Chest Physicians recommend that these medicines only be used in children age 15 years and older. The FDA recommends that OTC cold and cough medicine be used in children 2 years of age and older. However, there is agreement in regard to which OTC medications should not be used in children under the age of four (or the age of two, depending upon which guidelines are used), and they are 1) certain antihistamines like brompheniramine, chlorpheniramine maleate, and diphenhydramine (Benadryl); 2) cough expectorants (guaifenesin); 3) cough suppressants (dextromethorphan, DM); and 4) decongestants (pseudoephedrine and phenylephrine). Aspirin should never be given to infants, children, and adolescents due to the possibility of a rare, but often severe and even fatal illness called Reye's syndrome. REFERENCES:FDA. "Most Young Children with a Cough or Cold Don't Need Medicines." July 18, 2017. FDA. "Use Caution When Giving Cough and Cold Products to Kids." Updated: Nov 04, 2016.
How Long Is a Cold or Flu Contagious?
Viruses cause the common cold and the flu. Early symptoms and signs for a cold and the flu are similar, however, flu symptoms are typically more severe than cold symptoms. Cold and flu viruses are transmitted typically via coughing or sneezing.
Hyothermia or extreme exposure to cold can be classified as either accidental hypothermia (unintentional cold exposure) and intentional hypothermia (generally induced for a medical procedure). Hypothermia is caused by exposure to extremely cold temperatures. Risk factors for hypothermia include cold exposure and/or certain medical conditions. Symptoms of hypothermia include shivering; increased heart rate, breathing rate, and blood pressure; apathy, confusion, slurred speech, no reflexes, and dilated pupils. Medical attention is generally necessary to treat hypothermia.
Adenovirus 14 (Killer Cold Virus)
Adenovirus infection, particularly Ad14, or the "killer cold virus" has been on the increase in the past two years. Symptoms range from those experienced with colds, sore throat, bronchitis, pneumonia, diarrhea, pinkeye, fever, bladder infection, and neurological conditions. Diagnosis and treatment options need to be discussed with your physician.
Cold, Flu, Allergy Treatments
Before treating a cold, the flu, or allergies with over-the-counter (OTC) medications, it's important to know what's causing the symptoms, which symptoms one wishes to relieve, and the active ingredients in the OTC product. Taking products that only contain the medications needed for relieving your symptoms prevents ingestion of unnecessary medications and reduces the chances of side effects.
Killer Cold Virus (Adenovirus Infection, Ad14)
Second Source article from Government
Diabetes and Safe Medications for Colds and the Flu: OTC Medication Guide
If you have diabetes and catch a cold or the flu, can be more difficult to recover from infections and their complications, for example, pneumonia. Home remedies and over-the-counter (OTC) drugs used for the treatment of the signs and symptoms of colds and the flu may affect blood sugar levels in people with diabetes.Some medications are OK to take if you have diabetes get a cold or the flu include nonsteroidal anti-inflammatory drugs or NSAIDs, like acetaminophen (Tylenol) and ibuprofen (Motrin) to control symptoms of fever and pain. Most cough syrups are safe to take; however, check with your pediatrician to see what medications are safe to give your child if he or she has type 1 or 2 diabetes. If you have diabetes and are sick with a cold or flu, you need to check your blood sugar levels more frequently. Continue taking your regular medications. Eat a diabetic low-glycemic index diet rich in antioxidants. To prevent colds and the flu drink at least eight 8 ounce glasses of water a day. To replenish fluids, drink sports drinks like Gatorade and Pedialyte to replenish electrolytes. Avoid people who are sick, sneezing, coughing, or have other symptoms of a cold or flu.
COVID-19 vs. Flu vs. Cold
When you're feeling sick, it can be difficult to distinguish the symptoms of a COVID-19 infection from the symptoms of the common cold or the flu (influenza). While fever is common with the flu and COVID-19, sneezing is typically only associated with colds. Though sore throats are typical with colds, they are uncommon with COVID-19 infections and the flu.
Are Cold Sores (Fever Blisters) Contagious?
About 20% of cases of cold sores are caused by herpes simplex virus type 2 (HSV-2), and approximately 80% of cold sores are caused by herpes simplex virus type 1 (HSV-1). Cold sores are transmitted by sharing utensils and razors, kissing, and oral sex. There is no cure for cold sores.
Cold vs. Flu
Though the common cold and flu share many signs and symptoms, they are caused by different viruses. Signs and symptoms include sneezing, sore throat, runny nose, fatigue, and cough. Treatment options for the cold and flu are similar and focus on reducing symptoms. Doctors may prescribe antivirals/neuraminidase inhibitors for the flu.
Sinus Infection vs. Cold
Viruses cause the common cold and most sinus infections. Bacterial and fungal infections may also cause a sinus infection. Signs and symptoms of colds and sinus infections include nasal irritation or dryness, sore throat, stuffy nose, nasal discharge/congestion, sneezing, and cough. Additional symptoms of sinus infections include sinus pressure behind the cheeks or eyes, facial pain when pressure is applied, bad breath, and thick yellow or green mucus. Treatment focuses on symptom relief.
Emphysema, Chronic Bronchitis, and Colds
If you have a COPD such as emphysema, avoiding chronic bronchitis and colds is important to avoid a more severe respiratory infection such as pneumonia. Avoiding cigarette smoking, practice good hygeine, stay away from crowds, and alerting your healthcare provider if you have a sinus infection or cold or cough that becomes worse. Treatment options depend upon the severity of the emphysema, bronchitis, or cold combination.
Treatment & Diagnosis
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Medications & Supplements
- fexofenadine/pseudoephedrine extended-release - oral, Allegra D
- pseudoephedrine/loratadine 24-hour tablet - oral, Claritin-D
- loratadine/pseudoephedrine sustained-release - oral, Claritin-D
- fexofenadine and pseudoephedrine (Allegra-D)
- Side Effects of Claritin-D (loratadine/pseudoephedrine)
- loratadine and pseudoephedrine (Alavert Allergy & Sinus, Claritin-D, Claritin-D 24 hour)
- pseudoephedrine (Oral, Afrinol, Sudafed)
- chlorpheniramine, pseudoephedrine
- guaifenesin and phenylephrine, Sudafed PE Non-Drying Sinus Caplets, (Entex, discontinued)
- guaifenesin/theophylline/pseudoephedrine elixir - oral, Broncomar-1
- guaifenesin/pseudoephedrine - oral, Duratuss, Maxifed
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration.