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Does Ortho Micronor (norethindrone) cause side effects?
Common side effects of Ortho Micronor include
- menstrual irregularity (frequent and irregular bleeding, long bleeding episodes, missed periods, delayed periods, heavy periods),
- breast tenderness,
- excessive unwanted hair growth,
- weight gain,
- fluid retention (edema),
- pain in extremities,
- genital discharge,
- breast pain,
- suppressed lactation, and
- withdrawal bleeding.
Serious side effects of Ortho Micronor include
- serious allergic reactions,
- yellowing skin and eyes (jaundice),
- ovarian cyst, and
- ectopic pregnancy.
Drug interactions of Ortho Micronor include medications that can decrease the blood levels of Ortho Micronor by increasing its elimination in the liver such as carbamazepine, phenobarbital, phenytoin, rifampin, St. John's wort, and bosentan.
Oral contraceptives such as Ortho Micronor are generally avoided during pregnancy. Use of Ortho Micronor during pregnancy has been associated with masculinization of female infants.
Small amounts of progestin pass into breast milk and are detectable in the infant. Use of birth control pills during such as Ortho Micronor lactation has been associated with decreased milk production. Ortho Micronor may be used by breastfeeding women.
What are the important side effects of Ortho Micronor (norethindrone)?
Common side effects of norethindrone include:
Other possible side effects of norethindrone include:
- Long bleeding episodes
- Lack of menstruation
- Weight gain
- Pain in extremity
- Genital discharge
- Breast pain
- Menstruation delayed
- Suppressed lactation
- Vaginal bleeding
- Heavy menstruation
- Withdrawal bleeding
Possible serious side effects of norethindrone include:
Ortho Micronor (norethindrone) side effects list for healthcare professionals
Adverse reactions reported with the use of POPs include:
- Menstrual irregularity is the most frequently reported side effect.
- Frequent and irregular bleeding are common, while long duration of bleeding episodes and amenorrhea are less likely.
- Headache, breast tenderness, nausea, and dizziness are increased among progestin-only oral contraceptive users in some studies.
- Androgenic side effects such as acne, hirsutism, and weight gain occur rarely.
What drugs interact with Ortho Micronor (norethindrone)?
The effectiveness of progestin-only pills is reduced by hepatic enzyme-inducing drugs such as the anticonvulsants phenytoin, carbamazepine, and barbiturates, and the antituberculosis drug rifampin. No significant interaction has been found with broad-spectrum antibiotics.
Interactions with Laboratory Tests
The following endocrine tests may be affected by progestin-only oral contraceptive use:
- Sex hormone-binding globulin (SHBG) concentrations may be decreased.
- Thyroxine concentrations may be decreased, due to a decrease in thyroid binding globulin (TBG).
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Choosing Your Birth Control Method
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Birth Control Quiz: Test Your Medical IQ
What is the best form of birth control? Take this quiz to find out about hormonal, surgical, barrier, and natural methods!
Related Disease Conditions
Birth Control Options
Birth control is available in a variety of methods and types. The method of birth control varies from person to person, and their preferences to either become pregnant or not. Examples of barrier methods include barrier methods (sponge, spermicides, condoms), hormonal methods (pill, patch), surgical sterilization (tubal ligation, vasectomy), natural methods, and the morning after pill. Side effects and risks of each birth control option should be reviewed prior to using any birth control method.
Which Birth Control Has Least Side Effects?
No form of birth control is free of side effects, but there are some that have the least noticeable ones.
Birth Control Pill vs. Depo-Provera Shot
Birth control pills (oral contraceptives) and the Depo-Provera shot are two hormonal methods of birth control. Both methods work by changing the hormone levels in your body, which prevents pregnancy, or conception. Differences between "the pill" and "the shot." Birth control pills are available as combination pills, which contain the hormones estrogen and progestin, or mini-pills that only contain progestin. In comparison to the Depo-Provera injection, which prevents pregnancy for three consecutive months. Both methods of birth control are very effective in preventing pregnancy. Both the combination pill (if you take them as directed) and shot are up to 99% effective in preventing pregnancy. While the mini-pill is only about 95% effective in preventing pregnancy. Both methods cause weight gain, and have other similar side effects like breast pain, soreness or tenderness, headaches, and mood changes. They may lead to decreased interest in sex in some women. There are differences between the other side effects of these methods (depending upon the method) that include breakthrough bleeding or spotting, acne, depression, fatigue, and weakness. Both oral contraceptives and the Depo-Provera shot have health risks associated with them, such as, heart attack, stroke, blood clots, and cervical cancer. Birth control pills appear to increase the risk of cervical cancer. Talk with your OB/GYN or other doctor or health care professional about which birth control method is right for you.
DVT and Birth Control Pills (Oral Contraceptives)
Deep vein thrombosis (DVT) is a blood clot that has traveled deep into the veins of the arm, pelvis, or lower extremities. Oral contraceptives or birth control pills can slightly increase a woman's risk for developing blood clots, including DVT. DVT symptoms and signs in the leg include leg or calf pain, redness, swelling, warmth, or leg cramps, and skin discoloration. If a blood clot in the leg is not treated, it can travel to the lungs, which can cause a pulmonary embolism (blood clot in the lung) or post-thrombotic syndrome, both of which can be fatal if not treated immediately. Increased risk factors for DVT and birth control pills include over 40 years of age, family history, smoking, and obesity. Other medical problems that increase the risks of blood clots, for example, lung or heart disease, or inflammatory bowel disease or IBD (Crohn's disease and ulcerative colitis (UC). Other options for preventing pregnancy include IUDs, birth control shots, condoms, diaphragms, and progestin-only oral contraceptives.
What Does Birth Control Do to Your Body?
Different birth control methods work in different manners. No birth control method is perfect and every procedure or method has a side effect.
What Is the Best Form of Birth Control?
What's "best" among birth control methods differs from person to person. What's right for one person may not be right for others. And a person’s needs may also change over time.
Treatment & Diagnosis
Medications & Supplements
- Birth Control Pills (List of Oral Contraceptives and Side Effects)
- Birth Control Pills vs. Nuvaring
- Birth control pills (oral contraceptives) vs. Plan B (levonorgestrel)
- Birth Control Pills vs. Condoms
- norethindrone (Nor QD, Nora-BE, Ortho Micronor)
- Birth Control Pills (Oral Contraceptives) vs. Patch (Ortho Evra)
- Birth Control Pills (Oral Contraceptive) vs. Depo-Provera (medroxyprogesterone injection)
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration.