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Does Lidoderm (lidocaine) cause side effects?
Lidoderm (lidocaine) is an amide-type, local anesthetic medication available in a patch form prescribed for relief of pain associated with postherpetic neuralgia. Lidocaine, like other local anesthetics causes a loss of sensation by reducing the flow of sodium in and out nerves to decrease the initiation and transfer of nerve signals.
Common side effects of Lidoderm include
- application site reactions (local burning, bruising, blisters, itching, irritation),
- blurred vision, and
- low blood pressure.
Serious side effects of Lidoderm include
- severe application site reactions (burning, stinging, irritation, swelling, or redness),
- sudden dizziness or drowsiness after medicine is applied,
- blurred vision,
- ringing in your ears, and
- unusual sensations of temperature.
Drug interactions of Lidoderm include anti-arrhythmia medications like amiodarone, propafenone, sotalol, tocainide, and mexiletine because such combinations can affect heart rate and rhythm and cause other additive side effects.
There are no adequate studies done on Lidoderm patches to determine safe and effective use in pregnant women.
Lidoderm (lidocaine) side effects list for healthcare professionals
Application Site Reactions
- During or immediately after treatment with Lidoderm (lidocaine patch 5%), the skin at the site of application may develop blisters, bruising, burning sensation, depigmentation, dermatitis, discoloration, edema, erythema, exfoliation, irritation, papules, petechia, pruritus, vesicles, or may be the locus of abnormal sensation.
- These reactions are generally mild and transient, resolving spontaneously within a few minutes to hours.
- Allergic and anaphylactoid reactions associated with lidocaine, although rare, can occur.
- They are characterized by angioedema, bronchospasm, dermatitis, dyspnea, hypersensitivity, laryngospasm, pruritus, shock, and urticaria.
- If they occur, they should be managed by conventional means. The detection of sensitivity by skin testing is of doubtful value.
Other Adverse Events
- Due to the nature and limitation of spontaneous reports in postmarketing surveillance, causality has not been established for additional reported adverse events including:
- Asthenia, confusion, disorientation, dizziness, headache, hyperesthesia, hypoesthesia, lightheadedness, metallic taste, nausea, nervousness, pain exacerbated, paresthesia, somnolence, taste alteration, vomiting, visual disturbances such as blurred vision, flushing, tinnitus, and tremor.
Systemic (Dose-Related) Reactions
- Systemic adverse reactions following appropriate use of Lidoderm are unlikely, due to the small dose absorbed. Systemic adverse effects of lidocaine are similar in nature to those observed with other amide local anesthetic agents, including CNS excitation and/or depression (light-headedness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, tinnitus, blurred or double vision, vomiting, sensations of heat, cold or numbness, twitching, tremors, convulsions, unconsciousness, respiratory depression and arrest).
- Excitatory CNS reactions may be brief or not occur at all, in which case the first manifestation may be drowsiness merging into unconsciousness. Cardiovascular manifestations may include bradycardia, hypotension and cardiovascular collapse leading to arrest.
What drugs interact with Lidoderm (lidocaine)?
- Lidoderm should be used with caution in patients receiving Class I antiarrhythmic drugs (such as tocainide and mexiletine) since the toxic effects are additive and potentially synergistic.
- When Lidoderm is used concomitantly with other products containing local anesthetic agents, the amount absorbed from all formulations must be considered.
Lidoderm (lidocaine) is an amide-type, local anesthetic medication available in a patch form prescribed for relief of pain associated with postherpetic neuralgia. Common side effects of Lidoderm include application site reactions (local burning, bruising, blisters, itching, irritation), lightheadedness, dizziness, nausea, nervousness, blurred vision, and low blood pressure. There are no adequate studies done on Lidoderm patches to determine safe and effective use in pregnant women. Lidocaine may enter breast milk in trace amounts; therefore, it is best to be cautious before using it in breastfeeding mothers.
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Related Disease Conditions
Shingles (Herpes Zoster)
Shingles, or herpes zoster, is a painful rash caused by the varicella zoster virus. Other shingles symptoms include headache, fever, nausea, and body aches. Treatment focuses on pain management and shortening the duration of the illness with antiviral medications.
Can You Have a Mild Case of Shingles?
The severity of shingles depends on various factors, such as age of the patient, general health condition of the patient, and the part of the body where shingles develops.
Is Shingles Contagious?
Shingles is an infection caused by the varicella-zoster virus. Shingles symptoms and signs include skin burning, numbness, and tingling along with a painful red, blistering rash. Shingles is contagious until all of the blisters have crusted over.
Occipital Neuralgia (Headache)
Occipital neuralgia is a type of headache that involves inflammation or irritation of occipital nerves. Signs and symptoms include a stabbing and throbbing head pain, and an aching pain in the upper back of the head and neck. Potential causes include infection, irritation, or trauma of the occipital nerves. This type of headache is diagnosed by physical examination findings and imaging tests. Treatment involves a multidisciplinary approach that includes massage, rest, physical therapy, heat, muscle relaxants, and anti-inflammatory drugs. Invasive procedures and even surgery may be considered if first-line treatments fail to bring relief from the chronic pain of this type of headache.
What Does a Shingles Rash Look Like at First?
The typical shingles red rash or blisters occur after pain, itching, and tingling. They are usually limited to one side of the face and body.
How Long Is Shingles Contagious?
Shingles is contagious from the time the blisters are oozing until the time the blisters have scabbed.
Pain that originates in the face is referred to as trigeminal neuralgia. This pain may be caused by: an injury, an infection in the face, a nerve disorder, or it can occur for no known reason. Trigeminal neuralgia can be treated with antiseizure medications. Some antidepressant drugs also have significant pain relieving effects.
Postherpetic neuralgia (PHN) is a painful complication of shingles. Symptoms include severe pain, itchy skin, and possible weakness or paralysis of the area. There is no treatment for postherpetic neuralgia that is effective for all patients.
What Happens When You Get Shingles When Pregnant?
Becoming infected with chickenpox during pregnancy could cause birth defects in your unborn child. Likewise, shingles could also cause problems for your unborn child. If you are pregnant and haven't had chickenpox, avoid exposure to infected people. Zostavax, the shingles vaccine, can reduce the incidence of shingles by half. Women should wait at least three months after receiving the vaccine before trying to get pregnant.
Treatment & Diagnosis
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Medications & Supplements
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration.