Does Cortenema (hydrocortisone enema) cause side effects?
Cortenema (hydrocortisone enema) is a corticosteroid used rectally for the treatment of ulcerative proctitis, inflamed hemorrhoids, and anal itching, burning, and inflammation caused by several conditions that affect the anal area.
Common side effects of Cortenema include
- local pain,
- rectal bleeding,
- allergic reaction,
- reduced wound healing,
- spinning sensation (vertigo), and
Serious side effects of Cortenema include
- high blood pressure,
- fluid retention,
- heart failure,
- sodium retention,
- low potassium,
- peptic ulcer,
- increased risk of diabetes,
- adrenal insufficiency, and
- growth suppression in children.
The risk of drug interactions from Cortenema is low because it is administered rectally.
Cortenema has not been adequately evaluated during pregnancy.
Hydrocortisone taken orally can appear in breast milk, and can have adverse effects on the baby. It is unknown if Cortenema administered rectally is absorbed in sufficient amounts to appear in breast milk. Consult your doctor before breastfeeding.
What are the important side effects of Cortenema (hydrocortisone enema)?
Side effects of hydrocortisone enema include:
- Local pain
- Rectal bleeding
Other side effects include:
Possible serious side effects include:
- High blood pressure
- Fluid retention
- Heart failure
- Sodium retention
- Low potassium
- Peptic ulcer
- Increased risk of diabetes
- Adrenal insufficiency
- Growth suppression in children
Cortenema (hydrocortisone enema) side effects list for healthcare professionals
Local pain or burning, and rectal bleeding attributed to Cortenema have been reported rarely. Apparent exacerbations or sensitivity reactions also occur rarely. The following adverse reactions should be kept in mind whenever corticosteroids are given by rectal administration.
Fluid and Electrolyte Disturbances
- Sodium retention;
- fluid retention;
- congestive heart failure in susceptible patients;
- potassium loss;
- hypokalemic alkalosis;
- Muscle weakness;
- steroid myopathy;
- loss of muscle mass;
- vertebral compression fractures;
- asceptic necrosis of femoral and humeral heads;
- pathologic fracture of long bones.
- Peptic ulcer with possible perforation and hemorrhage;
- abdominal distention;
- ulcerative esophagitis.
- Impaired wound healing;
- thin fragile skin;
- petechiae and ecchymoses;
- facial erythema;
- increased sweating;
- may suppress reactions to skin tests.
- increased intracranial pressure with papilledema (pseudo-tumor cerebri) usually after treatment;
- Menstrual irregularities;
- development of Cushingoid state;
- suppression of growth in pediatric patients;
- secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness, decreased carbohydrate tolerance;
- manifestations of latent diabetes requirements for insulin or oral hypoglycemic agents in diabetics.
- Posterior subcapsular cataracts;
- increased intraocular pressure;
- Negative nitrogen balance due to protein catabolism.
Cortenema (hydrocortisone enema) is a corticosteroid used rectally for the treatment of ulcerative proctitis, inflamed hemorrhoids, and anal itching, burning, and inflammation caused by several conditions that affect the anal area. Common side effects of Cortenema include local pain, burning, rectal bleeding, allergic reaction, reduced wound healing, spinning sensation (vertigo), and headache. Cortenema has not been adequately evaluated during pregnancy. Hydrocortisone taken orally can appear in breast milk, and can have adverse effects on the baby.
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Related Disease Conditions
Hemorrhoids (Internal and External)
Hemorrhoids (piles) are swollen veins in the rectum and anus. Causes include pregnancy, obesity, diarrhea, low-fiber diet, and prolonged sitting on the toilet. Treatment varies depending upon the severity of the hemorrhoids. Some treatment options include over-the-counter creams and suppositories, stool softeners, warm sitz baths, and hemorrhoidectomies.
How to Stop Anal Itching
Anal itching is the irritation of the skin at the exit of the rectum, known as the anus, accompanied by the desire to scratch. Causes include everything from irritating foods we eat, to certain diseases, and infections. Treatment options include over-the-counter medications, using moist pads, and gentle cleaning and drying of the anus.
Ulcerative Colitis Diet Plan
An ulcerative colitis diet plan can help a person with the disease avoid foods and drinks that trigger flares. There also are foods that can soothe ulcerative colitis symptoms during a flare. Types of ulcerative colitis plans include a high-calorie diet, a lactose-free diet, a low-fat diet, a low-fiber diet (low-residue diet), or a low-salt diet. Self-management of ulcerative colitis using healthy lifestyle habits and a nutrient rich diet can be effective in management of the disease. Learn what foods to avoid that aggravate, and what foods help symptoms of the disease and increase bowel inflammation.
An anal fissure is a small tear or cut in the skin lining of the anus. Pain and/or rectal bleeding during bowel movements are common symptoms of anal fissures. Treatment includes increasing liquid intake, using stool softeners, prescription medications, and surgery.
How Long Do Thrombosed External Hemorrhoids Last?
Many thrombosed external hemorrhoids may go away within a few weeks. Pain may improve within 7-10 days without surgery and may disappear within 2-3 weeks.
Ulcerative colitis is a chronic inflammation of the colon. Symptoms and signs include abdominal pain, diarrhea, and rectal bleeding. Ulcerative colitis is closely related to Crohn's disease, and together they are referred to as inflammatory bowel disease. Treatment depends upon the type of ulcerative colitis diagnosed.
Crohn's Disease vs. Ulcerative Colitis
Crohn's disease and ulcerative colitis are diseases that cause inflammation of part of or the entire digestive tract (GI). Crohn's affects the entire GI tract (from the mouth to the anus), while ulcerative colitis or ulcerative colitis only affects the large and small intestine and ilium. Researchers do not know the exact cause of either disease. About 20% of people with Crohn's disease also have a family member with the disease. Researchers believe that certain factors may play a role in causing UC. Both Crohn's disease and ulcerative colitis are a type of inflammatory bowel disease or IBD. Crohn's disease and ulcerative colitis both have similar symptoms and signs, for example, nausea, loss of appetite, fatigue, weight loss, episodic and/or persistent diarrhea, fever, abdominal pain and cramping, rectal bleeding, bloody stools, joint pain and soreness, eye redness, or pain. Symptoms unique to Crohn’s disease include anemia and skin changes. Symptoms of unique to ulcerative colitis include certain rashes, and an urgency to defecate (have a bowel movement). Doctors diagnose both diseases with similar tests and procedures. While there is no cure for either disease, doctors and other health care professionals can help you treat disease flares, and manage your Crohn's or ulcerative colitis with medication, diet, nutritional supplements, and/or surgery.
Home Remedies for Hemorrhoids
Hemorrhoids are enlarged, swollen veins in the lowest part of the rectum and anus. These veins bulge and get irritated, especially when the patient defecates, and cause bleeding. Hemorrhoids are also commonly called piles. It is one of the most common causes of rectal bleeding.
When Should You Go to the Doctor for Hemorrhoids?
If you're dealing with painful or bleeding hemorrhoids, you're not alone. About one in 20 Americans have hemorrhoids, and that includes half of all adults over age 50.
What Is the Life Expectancy of Someone With Ulcerative Colitis?
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that affects the inner lining of the large intestine (large bowel) leading to erosion and ulcers. It is a lifelong illness with no specific cause or cure.
Is Ulcerative Colitis Curable?
Ulcerative colitis is an inflammatory bowel disease (IBD) that affects the inner lining of the large intestine (large bowel or colon) leading to erosion and ulcers. It is also associated with various manifestations outside of the colon, such as inflammation of the eyes, joints, skin, and lungs. Ulcerative colitis is a lifelong illness with no specific cause or cure. Patients have repeated cycles of flare-ups and disappearance of the disease.
How Do Hemorrhoids Go Away?
Hemorrhoid symptoms may go away with diet and lifestyle modifications. You must, however, seek immediate medical care if your symptoms do not go away in a week or you experience symptoms.
What Is the Best Treatment for Ulcerative Colitis?
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that affects the inner lining of the large intestine (large bowel) leading to erosion and ulcers. It is a lifelong illness with no specific cause or cure. Patients have repeated cycles of flare-ups and remission with potential extraintestinal (beyond the bowel) manifestations, such as joint pain, eye pain, and skin rashes.
Can Ulcerative Colitis Be Cured With Surgery?
Ulcerative colitis is a chronic inflammatory condition of the colon (the large bowel) characterized by frequent bloody diarrhea (10-30 episodes) throughout the day. Medicines can only reduce the intensity of its symptoms and surgery is the only option to cure it.
How Serious Is Ulcerative Colitis?
Ulcerative colitis (UC) is a lifelong disease with constant periods of flare-ups and remissions (periods without symptoms, which may last for weeks or years). Presently, there is no permanent medical cure for it, but there are various medications that can provide symptomatic relief, reduce inflammation and manage flare-ups.
Treatment & Diagnosis
Medications & Supplements
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Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration.