What is Ephedrine?
Ephedrine is a central nervous system stimulant used to treat bronchospasm due to asthma and nasal congestion. It is also used illegally for weight loss and for performance enhancement diet supplements.
Ephedrine directly stimulates alpha and beta-adrenergic receptors and increases the release of norepinephrine. Its actions include relaxation of bronchioles, increased heart rate and contractility, and increased blood pressure.
Ephedrine also causes blood vessels in the nasal passages to shrink (vasoconstrict). Vasoconstriction reduces nasal congestion by preventing fluid from draining from blood vessels into the lining of the nasal passages.
Drug interactions of ephedrine include monoamine oxidase inhibitors (MAOIs), for example, rasagiline, selegiline, isocarboxazid, phenelzine, and tranylcypromine, because combining MAOIs with ephedrine can cause an acute hypertensive episode.
What are the side effects of Ephedrine?
What are the common side effects of ephedrine?
Common side effects of ephedrine include
What are the serious side effects of ephedrine?
Serious side effects of ephedrine include
Is Ephedrine addictive?
Drug Abuse And Dependence
Prolonged abuse of Ephedrine Sulfate Injection, USP can lead to symptoms of paranoid schizophrenia. When this occurs, patients exhibit such physical signs as
Some measure of tolerance may develop with prolonged or excessive use but addiction does not occur. Temporary cessation of medication and subsequent readministration restores its effectiveness.
What drugs interact with Ephedrine?
- Concurrent use of ephedrine sulfate with general anesthetics, especially cyclopropane or halogenated hydrocarbons or digitalis glycosides may cause cardiac arrhythmias, since these medications may sensitize the myocardium to the effects of ephedrine sulfate.
- Therapeutic doses of ephedrine sulfate can inhibit the hypotensive effect of guanethidine, bethanidine, and debrisoquin by displacing the adrenergic blockers from their site of action in the sympathetic neurons.
- The effect in man is seen as a relative or a complete blockade of the antihypertensive drug by a sudden rise in blood pressure.
- Concomitant use of Ephedrine Sulfate Injection, USP and oxytocics may cause severe hypotension.
- Monoamine oxidase inhibitors may potentiate the pressor effect of ephedrine sulfate, possibly resulting in a hypertensive crisis.
- Ephedrine Sulfate Injection, USP should not be administered during or within 14 days following the administration of MAO inhibitors.
Ephedrine side effects list for healthcare professionals
With large doses of ephedrine sulfate most patients will experience
Some patients have
Multimedia: Slideshows, Images & Quizzes
What Is Asthma? Symptoms, Causes, and Treatments
What is asthma? Learn information about asthma, a chronic disease of the bronchiole tubes. Discover information about asthma...
Asthma is a chronic disease of the airways of the lungs, which can be managed with proper treatment. Triggered by two main...
Asthma: Asthma and the Weather
Does the weather affect your asthma? Find out how heat, cold and thunderstorms can make it hard to breathe -- and what you can do...
Asthma and Your Diet: Foods That Help and Hurt
Even though there's no specific asthma diet that can help your condition, certain foods may help or harm your breathing. Learn...
Asthma: Natural Ways to Ease Asthma Symptoms
You can do more than take medication to manage your asthma. Several other things can help you breathe more easily.
What is Asthma? Asthma Myths Debunked
What are asthma myths and facts? There is currently no cure for asthma, and no specific, single cause for asthma has been...
Asthma Attacks: Triggers, Symptoms, and Treatment
Asthma symptoms include coughing, wheezing, headache, fatigue, dark circles under the eyes, trouble sleeping, and loss of...
Worst Smog Cities in Pictures: Air Pollution, Ozone, and Asthma
Learn the worst smog cities in America. See the 10 cities with the most polluted, unclean and smoggy air.
Related Disease Conditions
Asthma is a condition in which hyperreactive airways constrict and result in symptoms like wheezing, coughing, and shortness of breath. Causes of asthma include genetics, environmental factors, personal history of allergies, and other factors. Asthma is diagnosed by a physician based on a patient's family history and results from lung function tests and other exams. Inhaled corticosteroids (ICS) and long-acting bronchodilators (LABAs) are used in the treatment of asthma. Generally, the prognosis for a patient with asthma is good. Exposure to allergens found on farms may protect against asthma symptoms.
Asthma: Over the Counter Treatment
Patients who have infrequent, mild bouts of asthma attacks may use over-the-counter (OTC) medications to treat their asthma symptoms. OTC asthma medicines are limited to epinephrine and ephedrine. These OTC drugs are best used with the guidance of a physician, as there may be side effects and the drugs may not be very effective.
COPD vs. Asthma (Differences and Similarities)
COPD (chronic obstructive pulmonary disease) and asthma both have common symptoms like coughing, wheezing, shortness of breath, and a tight feeling in the chest. COPD is caused by tobacco smoking, while asthma is caused by your inherited genetic makeup and their interactions with the environment. Risk factors for asthma are obesity, exposure to cigarette smoke (even secondhand smoke), and personal history of hay fever. There is no cure for either disease, but symptoms can be managed with medication. A person with asthma has a better prognosis and life expectancy than someone with COPD.
There are two types of asthma medications: long-term control with anti-inflammatory drugs and quick relief from bronchodilators. Asthma medicines may be inhaled using a metered-dose inhaler or nebulizer or they may be taken orally. People with high blood pressure, diabetes, thyroid disease, or heart disease shouldn't take OTC asthma drugs like Primatene Mist and Bronkaid.
What Is the Treatment for Asthmatic Bronchitis?
Asthmatic bronchitis refers to inflammation of the bronchial tubes carrying air inside the lungs that occurs because of asthma. Treatment for asthmatic bronchitis involves bronchodilators, steroids, treating secretions, leukotriene inhibitors, antibiotics, oxygen administration and avoiding triggers.
What Is Asthma? 19 Complex Facts
There are many unusual symptoms of asthma, including sighing, difficulty sleeping, anxiety, chronic cough, recurrent walking pneumonia, and rapid breathing. These symptoms may vary from individual to individual. These asthma complexities make it difficult to accurately diagnose and treat asthma.
How Can I Treat My Child's Asthma at Home?
Treatment of a child’s asthma involves following an action plan developed in consultation with your child’s pediatrician. Severe asthmatic attacks require immediate medical attention and treatment at the hospital.
Asthma in Children
Asthma in children manifests with symptoms such as coughing and wheezing. Rates of asthma in children are increasing. Asthma in children is usually diagnosed based on the description of symptoms. Lung function tests may also be used. A variety of medications are used for the treatment of childhood asthma.
Can Asthma Damage Your Lungs?
Asthma inflames the inner lining of the respiratory tubes and tightens the smooth muscles surrounding the airways, and can cause irreversible damage to your lungs if the condition is not controlled well.
How Long Does Asthmatic Bronchitis Last?
The duration of the disease usually depends on the patient’s overall health and age. In patients with acute bronchitis symptoms may last less than 10 days. In patients with severe asthmatic bronchitis, the symptoms are recurrent and usually last between 30 days to even 2 years with flares and remissions.
Can Asthma Go Away on Its Own?
Asthma is a long-term condition for many people, particularly if it first develops when you're an adult. In children, it sometimes goes away or improves during the teenage years, but can come back later in life.
Occupational asthma is a type of asthma caused by exposure to a substance in the workplace. Symptoms and signs include wheezing, chest tightness, and shortness of breath. The usual treatment for occupational asthma involves removal from exposure and the use of bronchodilators and inhaled anti-inflammatory medicines.
Adult-onset asthma is asthma that is diagnosed in people over 20 years of age. Symptoms include wheezing, coughing, shortness of breath and difficulty breathing. Treatment may involve anti-inflammatory medications or bronchodilators.
What Are the Four Types of Asthma?
Asthma is a chronic inflammatory disease of the airways (bronchi). Bronchi generally allow for the passage of air in and out of the lungs. In asthma, these airways develop hypersensitivity, inflammation, and narrowing. This causes difficulty in breathing. The four types are mild intermittent, mild persistent, moderate persistent and severe persistent.
Exercise-induced asthma is asthma triggered by vigorous exercise. Symptoms include coughing, shortness of breath, chest tightness, wheezing, and fatigue while exercising. Preventing exercise-induced asthma attacks involves using inhaled medicines before exercising, performing warm-up exercises and cooling down afterward, avoiding exercising outdoors when pollen counts are high, restricting exercise when you have a viral infection, and wearing a mask over your nose and mouth when exercising in cold weather.
What 5 Things Signal an Asthma Attack?
Understand the five symptoms of an asthma attack to better get the treatment you need during an episode.
What Are the Symptoms of Eosinophilic Asthma?
Eosinophilic asthma is a type of asthma that is hard to manage and quite severe. Here are the symptoms of this respiratory condition.
What Is the Main Cause of Bronchial Asthma?
The main cause of bronchial asthma is genetic makeup interacting with environmental triggers which produce symptoms such as severe attacks that can only be treated with short-lived relief that does not prevent a recurrence.
What Is the Best Treatment for Asthma?
Depending on the severity of your asthma, treatment may include quick-relief or controller medicines, a combination of both or the use of biologics.
How Do You Know if Your Baby Has Asthma?
Properly diagnosing and managing asthma in babies and young children can be challenging. However, be on the lookout for these signs and symptoms.
Can Asthma Be Genetic?
While asthma genes are inherited in families, the risks of developing the condition are half due to genetic susceptibility and half due to environmental factors.
What Is Winter Asthma?
Why is your asthma worse in the colder months? Learn about causes of winter asthma and what you can do now to create an action plan.
What Is Severe Asthma?
Asthma is a chronic inflammatory lung disease caused due to the airway’s hypersensitive response to allergic stimuli. Severe asthma or status asthmaticus is defined as asthma that is uncontrolled, despite adherence with maximal optimized therapy and treatment of contributory factors or asthma that worsens when high dose treatment is decreased.
What Class Is Severe Asthma?
Asthma is termed as a chronic inflammatory lung disease caused by the airway’s hypersensitive response to allergic stimuli (dust, pollen, pollution, smoke or unhygienic conditions). This results in the narrowing of airway passages, making it hard to breathe. It is often genetic and passed down from families and precipitated during childhood.
Treatment & Diagnosis
- Asthma FAQs
- What if I Get COVID-19 with Asthma?
- Methotrexate Spares Steroids in Asthmatics
- Asthma Rates Increasing
- Exercise Preventing Asthma?
- Asthma in Women, Asthma in Pregnancy
- Can Asthma Go Away and Come Back?
- What Are the Side Effects of Asthma Inhalers?
- Does Altitude Affect Asthma?
- What Is Exercise-Induced Asthma?
- Can Asthma Medication Hide Churg-Strauss Syndrome?
- Best Exercises for Asthma: Yoga, Swimming, Biking, and Walking
- Does Stress Cause Asthma?
- Can Asthma Cause a Heart Attack?
- What Causes Asthma?
Medications & Supplements
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration.