What is Ephedrine?
Ephedrine is a central nervous system stimulant used to treat bronchospasm due to asthma and nasal congestion. It is also used illegally for weight loss and for performance enhancement diet supplements.
Ephedrine directly stimulates alpha and beta-adrenergic receptors and increases the release of norepinephrine. Its actions include relaxation of bronchioles, increased heart rate and contractility, and increased blood pressure.
Ephedrine also causes blood vessels in the nasal passages to shrink (vasoconstrict). Vasoconstriction reduces nasal congestion by preventing fluid from draining from blood vessels into the lining of the nasal passages.
Drug interactions of ephedrine include monoamine oxidase inhibitors (MAOIs), for example, rasagiline, selegiline, isocarboxazid, phenelzine, and tranylcypromine, because combining MAOIs with ephedrine can cause an acute hypertensive episode.
What are the side effects of Ephedrine?
What are the common side effects of ephedrine?
Common side effects of ephedrine include
What are the serious side effects of ephedrine?
Serious side effects of ephedrine include
Is Ephedrine addictive?
Drug Abuse And Dependence
Prolonged abuse of Ephedrine Sulfate Injection, USP can lead to symptoms of paranoid schizophrenia. When this occurs, patients exhibit such physical signs as
Some measure of tolerance may develop with prolonged or excessive use but addiction does not occur. Temporary cessation of medication and subsequent readministration restores its effectiveness.
What drugs interact with Ephedrine?
- Concurrent use of ephedrine sulfate with general anesthetics, especially cyclopropane or halogenated hydrocarbons or digitalis glycosides may cause cardiac arrhythmias, since these medications may sensitize the myocardium to the effects of ephedrine sulfate.
- Therapeutic doses of ephedrine sulfate can inhibit the hypotensive effect of guanethidine, bethanidine, and debrisoquin by displacing the adrenergic blockers from their site of action in the sympathetic neurons.
- The effect in man is seen as a relative or a complete blockade of the antihypertensive drug by a sudden rise in blood pressure.
- Concomitant use of Ephedrine Sulfate Injection, USP and oxytocics may cause severe hypotension.
- Monoamine oxidase inhibitors may potentiate the pressor effect of ephedrine sulfate, possibly resulting in a hypertensive crisis.
- Ephedrine Sulfate Injection, USP should not be administered during or within 14 days following the administration of MAO inhibitors.
Ephedrine side effects list for healthcare professionals
With large doses of ephedrine sulfate most patients will experience
Some patients have
Ephedrine is a central nervous system stimulant used to treat bronchospasm due to asthma and nasal congestion. It is also used illegally for weight loss and for performance enhancement diet supplements. Common side effects of ephedrine include nausea, vomiting, tremor, headache, and dizziness. Serious side effects of ephedrine include high blood pressure, palpitations, fast heartbeat, seizures, and death. Ephedrine has not been adequately studied in pregnant women or in women who are breastfeeding.
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Related Disease Conditions
COPD vs. Asthma (Differences and Similarities)
COPD (chronic obstructive pulmonary disease) and asthma both have common symptoms like coughing, wheezing, shortness of breath, and a tight feeling in the chest. COPD is caused by tobacco smoking, while asthma is caused by your inherited genetic makeup and their interactions with the environment. Risk factors for asthma are obesity, exposure to cigarette smoke (even secondhand smoke), and personal history of hay fever. There is no cure for either disease, but symptoms can be managed with medication. A person with asthma has a better prognosis and life expectancy than someone with COPD.
Asthma is a condition in which hyperreactive airways constrict and result in symptoms like wheezing, coughing, and shortness of breath. Causes of asthma include genetics, environmental factors, personal history of allergies, and other factors. Asthma is diagnosed by a physician based on a patient's family history and results from lung function tests and other exams. Inhaled corticosteroids (ICS) and long-acting bronchodilators (LABAs) are used in the treatment of asthma. Generally, the prognosis for a patient with asthma is good. Exposure to allergens found on farms may protect against asthma symptoms.
Asthma Over-the-Counter Treatment
Patients who have infrequent, mild bouts of asthma attacks may use over-the-counter (OTC) medications to treat their asthma symptoms. OTC asthma medicines are limited to epinephrine and ephedrine. These OTC drugs are best used with the guidance of a physician, as there may be side effects and the drugs may not be very effective.
How Can I Treat My Child's Asthma at Home?
Treatment of a child's asthma involves following an action plan developed in consultation with your child's pediatrician. Severe asthmatic attacks require immediate medical attention and treatment at the hospital.
What Is the Treatment for Asthmatic Bronchitis?
Asthmatic bronchitis refers to inflammation of the bronchial tubes carrying air inside the lungs that occurs because of asthma. Treatment for asthmatic bronchitis involves bronchodilators, steroids, treating secretions, leukotriene inhibitors, antibiotics, oxygen administration and avoiding triggers.
There are two types of asthma medications: long-term control with anti-inflammatory drugs and quick relief from bronchodilators. Asthma medicines may be inhaled using a metered-dose inhaler or nebulizer or they may be taken orally. People with high blood pressure, diabetes, thyroid disease, or heart disease shouldn't take OTC asthma drugs like Primatene Mist and Bronkaid.
Can Asthma Damage Your Lungs?
Asthma inflames the inner lining of the respiratory tubes and tightens the smooth muscles surrounding the airways, and can cause irreversible damage to your lungs if the condition is not controlled well.
How Long Does Asthmatic Bronchitis Last?
The duration of the disease usually depends on the patient’s overall health and age. In patients with acute bronchitis symptoms may last less than 10 days. In patients with severe asthmatic bronchitis, the symptoms are recurrent and usually last between 30 days to even 2 years with flares and remissions.
Asthma in Children
Asthma in children manifests with symptoms such as coughing and wheezing. Rates of asthma in children are increasing. Asthma in children is usually diagnosed based on the description of symptoms. Lung function tests may also be used. A variety of medications are used for the treatment of childhood asthma.
Adult-onset asthma is asthma that is diagnosed in people over 20 years of age. Symptoms include wheezing, coughing, shortness of breath and difficulty breathing. Treatment may involve anti-inflammatory medications or bronchodilators.
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Can Asthma Go Away on Its Own?
Asthma is a long-term condition for many people, particularly if it first develops when you're an adult. In children, it sometimes goes away or improves during the teenage years, but can come back later in life.
What Is the Main Cause of Bronchial Asthma?
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What Are the Four Types of Asthma?
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Can Asthma Be Genetic?
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Occupational asthma is a type of asthma caused by exposure to a substance in the workplace. Symptoms and signs include wheezing, chest tightness, and shortness of breath. The usual treatment for occupational asthma involves removal from exposure and the use of bronchodilators and inhaled anti-inflammatory medicines.
What 5 Things Signal an Asthma Attack?
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How Do You Know if Your Baby Has Asthma?
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What Is the Best Treatment for Asthma?
Depending on the severity of your asthma, treatment may include quick-relief or controller medicines, a combination of both or the use of biologics.
What Is Severe Asthma?
Asthma is a chronic inflammatory lung disease caused due to the airway’s hypersensitive response to allergic stimuli. Severe asthma or status asthmaticus is defined as asthma that is uncontrolled, despite adherence with maximal optimized therapy and treatment of contributory factors or asthma that worsens when high dose treatment is decreased.
What Class Is Severe Asthma?
Asthma is termed as a chronic inflammatory lung disease caused by the airway’s hypersensitive response to allergic stimuli (dust, pollen, pollution, smoke or unhygienic conditions). This results in the narrowing of airway passages, making it hard to breathe. It is often genetic and passed down from families and precipitated during childhood.
Treatment & Diagnosis
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Medications & Supplements
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration.