Does Tagamet HB (cimetidine) cause side effects?
Tagamet HB (cimetidine) is an H2 (histamine-2) blocker used to relieve heartburn associated with acid indigestion and sour stomach and to prevent heartburn brought on by eating or drinking certain foods and beverages.
Tagamet HB blocks the production of acid by acid-producing cells in the stomach. Histamine is a naturally-occurring chemical that stimulates cells in the stomach (parietal cells) to produce acid. H2-blockers inhibit the action of histamine on the cells, thus reducing the production of acid by the stomach.
Since excessive stomach acid can damage the esophagus, stomach, and duodenum by reflux and lead to inflammation and ulceration, reducing stomach acid prevents and allows acid-induced inflammation and ulcers to heal.
Common side effects of Tagamet HB include
Serious side effects of Tagamet HB include
- confusion and hallucinations (usually in elderly or critically ill patients),
- enlargement of the breasts,
- impotence (usually seen in patients on high doses for prolonged periods),
- decreased white blood cell counts,
- irregular heartbeat,
- visual changes,
- allergic reactions, and
- Tagamet HB also may increase the blood levels phenytoin, theophylline, lidocaine, amiodarone, metronidazole, loratadine, calcium channel blockers, nifedipine, bupropion, carbamazepine, and fluvastatin.
- Because Tagamet HB reduces stomach acid, it may reduce the absorption of drugs (for example, ketoconazole) that are best absorbed in acidic conditions. Such drugs should be administered at least 2 hours before the administration of Tagamet HB.
What are the important side effects of Tagamet HB (cimetidine)?
Side effects due to cimetidine are rare and generally reversible once the medication is stopped. Minor side effects include:
Major side effects include confusion and hallucinations (usually in elderly or critically ill patients), enlargement of the breasts; impotence (usually seen in patients on high doses for prolonged periods); decreased white blood cell counts.
Other side effects include:
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Related Disease Conditions
Heartburn is a burning sensation experienced from acid reflux (GERD). Symptoms of heartburn include chest pain, burning in the throat, difficulty swallowing, the feeling of food sticking in the throat, and a burning feeling in the chest. Causes of heartburn include dietary habits, lifestyle habits, and medical causes. Treatments for heartburn include lifestyle changes, OTC medication,prescription medication, and surgery.
GERD (Acid Reflux, Heartburn)
GERD (gastroesophageal reflux disease) is a condition in which the acidified liquid contents of the stomach backs up into the esophagus. The symptoms of uncomplicated GERD are: heartburn, regurgitation, and nausea. Effective treatment is available for most patients with GERD.
Ways to Relieve Acid Reflux (GERD, Heartburn)
Most people have experienced some sort of pain or discomfort following a large meal or a particular food that didn’t quite agree with their stomach. Acid reflux symptoms can happen without a specific underlying condition.
What Is the Quickest Way to Get Rid of Heartburn?
Taking antacids is considered the quickest way to get rid of heartburn. These over-the-counter medications help neutralize stomach acid. They are one of the first recommended treatments. They may provide quick relief. However, antacid overuse can cause problems such as diarrhea or chronic kidney disease, especially if they contain aluminum and magnesium.
Heartburn vs. Acid Reflux (Differences and Similarities)
Heartburn and acid reflux are not the same thing. Heartburn is actually a symptom of acid reflux. Heartburn gets its name because it feels like a burning sensation around the heart. Another symptom that occurs with heartburn is a bitter or sour taste in the mouth, usually when you eat or lye down. Heartburn affects more than 60 million people in the US at least once a month. Acid reflux, or GERD, occurs when stomach acid backs up into the esophagus, which irritates it. Heartburn is just one symptom of acid reflux. Other symptoms of acid reflux include: Belching Nausea after eating A feeling of fullness during or after eating Abdominal bloating Upset stomach Belching Wheezing Reflux laryngitis A tightness in the throat Problems swallowing Indigestion In some people, vomiting Causes of acid reflux and heartburn include: Being obese Slouching (poor posture) Medications like calcium channel blockers, theophylline, nitrates, and antihistamines Foods and drinks like caffeine, citrus fruits and vegetables, alcohol, and chocolate Pregnancy Diabetes Increase in stomach acid Eating a heavy meal Eating before bed The treatment for heartburn and acid reflux is to treat the underlying cause, for example, GERD, with over-the-counter (OTC) medicine, prescription medicine, natural remedies, and lifestyle changes like a eating a healthy, less fatty, spicy diet, not eating big meals, not eating before bed, and getting regular exercise to improve your posture.Sometimes a heart attack can mimic heartburn and acid reflux because they feel very similar. If you have symptoms of chest pain, tightness in the chest, heartburn, acid reflux, jaw, tooth, or head pain; shortness of breath, nausea, vomiting, sweating, discomfort in the upper middle of the abdomen, arm or upper back pain, or the general feeling of being ill, go to the nearest Emergency Department immediately because these are the symptoms of a heart attack.REFERENCES:American College of Gastroenterology. "Acid Reflux." 2017.<http://patients.gi.org/topics/acid-reflux/> familydoctor.org. "Heartburn." Updated: Mar 2014.<https://familydoctor.org/condition/heartburn/> National Library of Medicine; PubMed Health. "Heartburn and GERD: Treatment options for GERD." Updated: Nov 18, 2015.<https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0072436/>
Heartburn During Pregnancy
Heartburn during pregnancy is quite common. During pregnancy the lower esophageal sphincter muscle becomes weakened , which likely occurs due to the effect of the high levels of the hormones estrogen and progesterone during pregnancy. Fortunately, this resolves after pregnancy. Management of heartburn during pregnancy are generally involves lifestyle changes and avoiding foods that promote heartburn, for example, don't smoke, avoid tight clothing, eat small, frequent meals, chew gum, or sip liquids.
Beyond Food: What Triggers Heartburn and GERD?
Heartburn is the burning sensation in the chest due to backflow or reflux of the acidic stomach contents into the food pipe (esophagus). Heartburn is a major symptom of gastroesophageal reflux disease or GERD.
Gastroesophageal Reflux Disease (GERD)
Second Source article from Government
Gastroesophageal Reflux Disease (GERD)
Second Source article from The Cleveland Clinic
Heart Attack vs. Heartburn
Heartburn is a symptom of another disease or medical problem and can be described as a feeling of burning in the chest accompanied by symptoms of nausea, vomiting, or a sour taste or food stuck in the back of the throat. Heart attack occurs when an artery in the heart is completely blocked by a blood clot, which causes that portion of heart muscle to die. Heart attack also has symptoms of chest pain, nausea, and vomiting, however, other warning signs and symptoms of a heart attack are unusual weakness or fatigue, and persistent and/or increased severity of symptoms over a few minutes. Heart attack is a life threatening emergency. If you think you or someone you are with is having a heart attack, call 911 immediately for urgent medical treatment. It may save your life.
Quick Relief For Heartburn
Heartburn refers to the burning sensation in the chest due to backflow or reflux of the acidic stomach contents into the food pipe (esophagus). If you are experiencing heartburn, you may ease the problem through various ways.
GERD: Is the Damage Reversible?
Gastroesophageal reflux disease or GERD is caused by the weakening of the lower esophageal sphincter (LES). LES is a group of muscles that act as a valve to prevent the acidic contents of the stomach from refluxing into the esophagus.
GERD (Acid Reflux) in Infants and Children
GERD (gastroesophageal reflux disease) is the upward movement of stomach content, including acid, into the esophagus and sometimes into or out of the mouth. Common symptoms of GERD in children include colic, feeding problems, poor growth, frequent vomiting or coughing, heartburn, regurgitation, recurrent wheezing, pneumonia, choking, or gagging. Treatment may involve elevating the child's bed, keeping the child upright after eating, limiting foods that seem to make the reflux worse, encouraging your child to exercise, and serving several small meals a day.
What Are the Symptoms of GERD in Adults?
Gastroesophageal reflux disease, or GERD, is when stomach acid, food, and fluids move up from the stomach to the esophagus. Learn more about GERD, its common symptoms, how it's diagnosed, and your treatment options.
How Do You Know If You Have Heartburn When Pregnant?
Heartburn is a common issue that affects many pregnant people. Learn the signs of heartburn in pregnancy, what causes it, how doctors diagnose it, and what you can do to treat it.
What Can Heartburn Be a Sign of?
Heartburn symptoms may indicate a bigger health concern. Learn more about heartburn, heartburn symptoms, heartburn related to other health conditions, how it's diagnosed, and your treatment options for heartburn.
What Causes Gastroesophageal Reflux Disease (GERD)?
Gastroesophageal reflux disease (GERD) is a chronic disorder in which acid reflux occurs at least two times a week for several weeks. Acid reflux is a condition in which the acidic stomach contents leak back in the food pipe (esophagus) and cause heartburn.
Treatment & Diagnosis
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Medications & Supplements
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration.