Does Loprox (ciclopirox) cause side effects?

Loprox (ciclopirox) is a broad-spectrum antifungal agent used to treat mild to moderate finger or toenail fungus, ringworm, jock itch, athlete's foot, tinea versicolor, and seborrheic dermatitis

Loprox inhibits the growth of dermatophytes, a type of fungus that grows on the skin, hair, and nails. When applied to skin a very small percentage is absorbed into the body. 

Common side effects of Loprox include

Serious side effects of Loprox include

  • unusual or severe itching,
  • redness,
  • burning,
  • dryness, or
  • irritation of treated skin.

Drug interactions of Loprox include other medications used to treat fungal infections at the same time. Nail polish or other cosmetic products should not be used on the treated nails. When applied to skin a very small amount of Loprox is absorbed into the body. 

There are no adequate or well-controlled studies of Loprox in pregnant women. Loprox should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. 

It is unknown if Loprox is excreted in breast milk. Because of a potential for side effects in the nursing infant, the physician must weigh the potential benefits and possible risks before prescribing Loprox to breastfeeding mothers.

What are the important side effects of Loprox (ciclopirox)?

Side effects of ciclopirox include:

Loprox (ciclopirox) side effects list for healthcare professionals

In clinical trials, 140 (39%) of 359 subjects treated with Loprox Gel (ciclopirox gel) reported adverse experiences, irrespective of relationship to test materials, which resulted in 8 subjects discontinuing treatment.

The most frequent experience reported was skin burning sensation upon application, which occurred in approximately 34% of seborrheic dermatitis patients and 7% of tinea pedis patients.

Adverse experiences occurring between 1% to 5% were contact dermatitis and pruritus. Other reactions that occurred in less than 1% included

What drugs interact with Loprox (ciclopirox)?

No information provided.

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Medically Reviewed on 1/4/2021
References
FDA Prescribing Information

Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration.