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Does Cefzil (cefprozil) cause side effects?
Cefzil (cefprozil) is a cephalosporin antibiotic effective against susceptible bacteria causing infections of the middle ear, tonsils (tonsillitis), throat (pharyngitis), larynx (laryngitis), bronchi (bronchitis), skin and soft tissues, and lungs (pneumonia).
Cephalosporins stop or slow the growth of bacterial cells by preventing bacteria from forming the cell wall that surrounds each cell. The cell wall protects bacteria from the external environment and keeps the contents of the cell together. Without a cell wall, bacteria are not able to survive.
Common side effects of Cefzil include
Serious but rare side effects of Cefzil include
- abnormal liver tests,
- allergic reactions, and
- pseudomembranous colitis, a potentially serious bacterial infection of the colon.
Drug interactions of Cefzil include probenecid, which may increase the blood concentration of Cefzil by decreasing excretion of Cefzil by the kidney. This interaction is sometimes used to enhance the effect of cephalosporins.
- Combining Cefzil with aminoglycosides (for example, tobramycin) produces additive bacterial killing effects but also may increase the risk of harmful effects to the kidney.
- Exenatide may delay or reduce the absorption of cephalosporins.
- Cephalosporins should be administered one hour before exenatide.
- Cefzil may cause false test results with some tests for sugar in the urine.
There are no adequate studies of Cefzil in pregnant women.
What are the important side effects of Cefzil (cefprozil)?
Cefprozil is generally well tolerated. The most common side effects are:
Rare side effects include abnormal liver tests and allergic reactions. Like most antibiotics cefprozil may cause a condition called pseudomembranous colitis, a potentially serious bacterial infection of the colon. Persons with phenylketonuria should be advised that the suspension contains phenylalanine.
Cefzil (cefprozil) side effects list for healthcare professionals
The adverse reactions to cefprozil are similar to those observed with other orally administered cephalosporins. Cefprozil was usually well tolerated in controlled clinical trials. Approximately 2% of patients discontinued cefprozil therapy due to adverse events.
The most common adverse effects observed in patients treated with cefprozil are:
- Elevations of AST (SGOT) (2%),
- ALT (SGPT) (2%),
- alkaline phosphatase (0.2%), and
- bilirubin values ( < 0.1%).
Such reactions have been reported more frequently in children than in adults. Signs and symptoms usually occur a few days after initiation of therapy and subside within a few days after cessation of therapy.
- Dizziness (1%),
- confusion, and
- somnolence have been reported rarely ( < 1%).
All were reversible.
The following adverse events, regardless of established causal relationship to CEFZIL (cefprozil), have been rarely reported during postmarketing surveillance:
- colitis (including pseudomembranous colitis),
- erythema multiforme,
- serum-sickness like reactions,
- Stevens-Johnson syndrome, and
Cephalosporin class paragraph
In addition to the adverse reactions listed above which have been observed in patients treated with cefprozil, the following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics:
- Aplastic anemia,
- hemolytic anemia,
- renal dysfunction,
- toxic epidermal necrolysis,
- toxic nephropathy,
- prolonged prothrombin time,
- positive Coombs' test,
- elevated LDH,
Several cephalosporins have been implicated in triggering seizures, particularly in patients with renal impairment, when the dosage was not reduced. If seizures associated with drug therapy occur, the drug should be discontinued. Anticonvulsant therapy can be given if clinically indicated.
What drugs interact with Cefzil (cefprozil)?
- Nephrotoxicity has been reported following concomitant administration of aminoglycoside antibiotics and cephalosporin antibiotics. Concomitant administration of probenecid doubled the AUC for cefprozil.
- The bioavailability of the capsule formulation of cefprozil was not affected when administered 5 minutes following an antacid.
Drug/Laboratory Test Interactions
- Cephalosporin antibiotics may produce a false positive reaction for glucose in the urine with copper reduction tests (Benedict's or Fehling's solution or with Clinitest tablets), but not with enzyme-based tests for glycosuria (eg, Clinistix).
- A false negative reaction may occur in the ferricyanide test for blood glucose.
- The presence of cefprozil in the blood does not interfere with the assay of plasma or urine creatinine by the alkaline picrate method.
Cefzil (cefprozil) is a cephalosporin antibiotic effective against susceptible bacteria causing infections of the middle ear, tonsils (tonsillitis), throat (pharyngitis), larynx (laryngitis), bronchi (bronchitis), skin and soft tissues, and lungs (pneumonia). Common side effects of Cefzil include diarrhea or loose stools, nausea, abdominal pain, vomiting, rash, and headache. There are no adequate studies of Cefzil in pregnant women. Small amounts of Cefzil are secreted in breast milk, but the effect on the infant is unknown.
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Tonsil stones are small clusters of calcifications that form when food, dead cells, mucus, and bacteria get stuck in the nooks and crannies of the tonsils. Tonsil stones are hard, appear as white or yellowish formations on the tonsils, and usually smell bad due to bacteria. If symptoms occur, they may include persistent bad breath, sore throat, difficulty swallowing, ear pain, and cough.
Ear Infection Home Treatment
Infections of the outer, middle, and inner ear usually are caused by viruses. Most outer (swimmer's ear) and middle ear (otitis media) infections can be treated at home with remedies like warm compresses for ear pain relief, tea tree, ginger, or garlic oil drops. Symptoms of an outer ear (swimmer's ear) and middle ear infection include mild to severe ear pain, pus draining from the ear, swelling and redness in the ear, and hearing problems. Middle and inner ear infections may cause fever, and balance problems. Inner ear infections also may cause nausea, vomiting, vertigo, ringing in the ear, and labyrinthitis (inflammation of the inner ear). Most outer and middle ear infections do not need antibiotics. Inner ear infections should be treated by a doctor specializing in ear and hearing problems.
Inner Ear Infection (Symptoms, Signs, Treatments, Home Remedies)
An inner ear infection or otitis interna is caused by viruses or bacteria and can occur in both adults and children. An inner ear infection can cause symptoms and signs, for example, a severe ear, dizziness, vertigo, nausea and vomiting, and vertigo. An inner ear infection also may cause inflammation of the inner ear or labyrinthitis. Inner ear infections are not contagious; however, the bacteria and viruses that cause the infection can be transmitted to other people. Good hygiene practices will help decrease the chances of the infection spreading to others. Inner ear infection symptoms and signs like ear pain and nausea may be relieved with home remedies or over the counter (OTC) medication. Some inner ear infections will need to be treated and cured with antibiotics or prescription pain or antinausea medication.
Pneumonia is inflammation of the lungs caused by fungi, bacteria, or viruses. Symptoms and signs include cough, fever, shortness of breath, and chills. Antibiotics treat pneumonia, and the choice of the antibiotic depends upon the cause of the infection.
Middle Ear Infection (Otitis Media)
Middle ear infection (otitis media) is inflammation of the middle ear. There are two forms of this type of ear infection, acute and chronic. Acute otitis media is generally short in duration, and chronic otitis media generally lasts several weeks. Babies, toddlers, and children with a middle ear infection may be irritable, pull and tug at their ears, and experience numerous other symptoms and signs. Treatment depends upon the type of ear infection.
Tonsillitis is a contagious infection with symptoms of bad breath, snoring, congestion, headache, hoarseness, laryngitis, and coughing up blood. Tonsillitis can be caused acute infection of the tonsils, and several types of bacteria or viruses (for example, strep throat or mononucleosis). There are two types of tonsillitis, acute and chronic. Acute tonsillitis lasts from one to two weeks while chronic tonsillitis can last from months to years. Treatment of tonsillitis and adenoids include antibiotics, over-the-counter medications, and home remedies to relieve pain and inflammation, for example, salt water gargle, slippery elm throat lozenges, sipping warm beverages and eating frozen foods (ice cream, popsicles), serrapeptase, papain, and andrographism Some people with chronic tonsillitis may need surgery (tonsillectomy or adenoidectomy).
Inner Ear Infection (Labyrinthitis)
Labyrinthitis is inflammation of the labyrinth (the part of the ear responsible for balance and hearing). Doctors do not know the exact cause of labyrinthitis; however, they often are associated viral infections of the inner ear. Symptoms of labyrinthitis are ear pain or earache, ear discharge, problems with balance and walking, ringing in the ears, dizziness, nausea, vomiting, and vertigo. Viral infections associated with labyrinthitis are contagious. Home remedies may help labyrinthitis symptoms and signs. Over-the-counter (OTC) and prescription medication may treat inner ear infections, labyrinthitis symptoms like vertigo and nausea, and help ear pain.
Laryngitis is an inflammation of the voice box (vocal cords). The most common cause of acute laryngitis is infection, which inflames the vocal cords. Symptoms may vary from degree of laryngitis and age of the person (laryngitis in infants and children is more commonly caused by croup). Common symptoms include a "barky" cough, a hoarse cough, fever, cold, runny nose, dry cough, and loss of voice. Chronic laryngitis generally lasts more than three weeks. Causes other than infection include smoking, excess coughing, GERD, and more. Treatment depends on the cause of laryngitis.
Is Pneumonia Contagious?
Pneumonia is inflammation of the lung usually caused by bacterial or viral infection (rarely, also by fungi) that causes the air sacs to fill with pus. If inflammation affects both lungs, the infection is termed double pneumonia. If it affects one lung, it is termed single pneumonia. If it affects only a certain lobe of a lung it's termed lobar pneumonia. Most pneumonias are caused by bacteria and viruses, but some pneumonias are caused by inhaling toxic chemicals that damage lung tissue.
Bronchitis (Acute) Contagoius Symptoms, Causes, Treatment, and Recovery Time
Bronchitis is inflammation of the airways in the lung. Acute bronchitis is is short in duration (10 to 20 days) in comparison with chronic bronchitis, which lasts for months to years. Causes of acute bronchitis include viruses and bacteria, which means it can be contagious. Acute bronchitis caused by environmental factors such as pollution or cigarette smoke is not contagious. Common symptoms for acute bronchitis include nasal congestion, cough, headache, sore throat, muscle aches, and fatigue. Acute bronchitis in children also my include runny nose, fever, and chest pain. Treatment for acute bronchitis are OTC pain relievers, cough suppressants (although not recommended in children), and rest. Infrequently antibiotics may be prescribed to treat acute bronchitis.
Is Tonsillitis Contagious?
Tonsillitis is a common infection, especially in kids. Tonsillitis is caused by viruses and bacteria like the flu and herpes simplex virus, and Streptococcus bacteria. These viruses and bacterium are spread person to person. Symptoms of tonsillitis are a yellow or white coating on the tonsils, throat pain, pain when swallowing, and hoarseness.
How Long Is Pneumonia Contagious?
Pneumonia may be contagious for 2-14 days. Usually, the goal of medications given for pneumonia is to limit the spread of the disease.
Reflux Laryngitis (Diet, Home Remedies, Medicine)
Reflux laryngitis is caused by acid refluxing back up through the esophagus and voice box. Reflux laryngitis causes irritation and inflammation of the lining of the esophagus, larynx, and throat; and can lead to symptoms, signs, and other problems like esophagitis, sinusitis, strictures, throat clearing, swallowing problems, asthma, chronic cough, and growths on the vocal cords. Typical symptoms of reflux laryngitis include heartburn, hoarseness, or a sensation of a foreign body in the throat. Reflux laryngitis can be treated with diet chanes, OTC medication, prescription medication, and lifestyle changes.
Chronic bronchitis is a cough that occurs daily with production of sputum that lasts for at least three months, two years in a row. Causes of chronic bronchitis include cigarette smoking, inhaled irritants, and underlying disease processes (such as asthma, or congestive heart failure). Symptoms include cough, shortness of breath, and wheezing. Treatments include bronchodilators and steroids. Complications of chronic bronchitis include COPD and emphysema.
Is Laryngitis Contagious?
Laryngitis is inflammation and swelling of the voice box (larynx). Causes of laryngitis are viral, bacterial, fungal, strenuous singing or talking, chemical irritants, and other underlying medical conditions. Symptoms of laryngitis are hoarseness, a weak or loss of voice, sore throat, dry throat, a tickling sensation in the back of the throat, or irritated or raw throat. Treatment of laryngitis depends upon the cause.
Second Source article from WebMD
Second Source article from Government
Second Source article from WebMD
Interstitial Lung Disease (Interstitial Pneumonia)
Interstitial lung disease refers to a variety of diseased that thicken the tissue between the lungs' air sacks. Viruses, bacteria, tobacco smoke, environmental factors, cancer, and heart or kidney failure can all cause interstitial lung disease. Shortness of breath, cough, and vascular problems are symptoms caused by interstitial lung disease, and their treatment depends on the underlying cause of the tissue thickening.
Laryngitis Home Remedies
Laryngitis is an inflammation of the larynx. Inflammation of the larynx is most often caused by viral infections, and have symptoms such as sore throat, cough, problems swallowing, and fever. The voice changes produced by laryngitis may last after the fever and other symptoms of the acute infection has gone away. The best natural home remedy to relieve pain and other symptoms caused by laryngitis include resting your voice and breathing humidified air often. Turning on hot water in the bathroom and then sitting in the steam can soothe and relive laryngitis symptoms. Acetaminophen (Tylenol) and anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil, Aleve) can relieve pain and inflammation caused by laryngitis. Don't give children aspirin to infants, toddlers, children and teens because of the risk of developing Reye's syndrome, which can be fatal. Home remedies like resting your voice and sitting in humidified air can cure laryngitis. Medications like anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil, Aleve) and acetaminophen (Tylenol) can relieve and soothe pain and symptoms caused by laryngitis.
Home Remedies for Tonsillitis: Treatment and Relief
Tonsillitis usually runs its course. Home remedies may help ease your/your child’s symptoms including getting plenty of rest, gargling, drinking water, washing your hands and taking over-the-counter pain relieving medication.
Will Tonsillitis Go Away on Its Own?
Tonsils are the two oval-shaped pads of tissue in the back of your throat. They help protect your body from infection. However, sometimes they get infected and inflamed (red and swollen) and this is called tonsillitis. Tonsillitis symptoms usually go away after three to four days.
Can Pneumonia Go Away On Its Own?
Mild pneumonia may be healed by body’s defense system. However severe cases of pneumonia require medical attention especially viral pneumonia.
Viral pneumonia: Symptoms, Causes And Treatment
Pneumonia is an infection in your lungs that is usually caused by bacteria, viruses or fungi. About 30% of pneumonia cases reported in the United States are viral. Symptoms include dry cough, fever, chills, difficulty breathing, chest pain and rapid breathing.
Can an Inner Ear Infection Cause Vertigo?
Vertigo, a sensation of feeling off balance, can be a symptom of an inner ear infection or other disorder. Learn more about vertigo, its causes, and treatments.
What Causes an Abscess in Your Throat (Peritonsillar Abscess)?
An abscess in your throat is a collection (or pocket) of pus in the space (peritonsillar space) that lies between each tonsil and wall of the throat. Medically, it is known as peritonsillar abscess or quinsy.
Laryngitis: Symptoms, Causes, and Treatments
Laryngitis is the inflammation of the voice box (larynx). If caused by a virus or bacteria, laryngitis may be contagious.
What Are the Main Causes of Bronchitis?
Bronchitis is an inflammation of the tubes that carry air to and from your lungs. Learn the signs of bronchitis, what causes bronchitis, how doctors diagnose bronchitis, and what you can do to treat bronchitis.
How Long Does Laryngitis Last?
What is laryngitis, and how do you know if you have laryngitis? Learn the signs of laryngitis and how to care for your throat if you have laryngitis.
How Do You Get Rid of Bronchitis Naturally?
Bronchitis is swelling of airways mostly due to a virus. Rarely, bacteria or fungi can also be the reason. Swelling in bronchial tubes may restrict air to and from your lungs. It typically causes a bad cough, chest discomfort, and fatigue. You may need to consult a doctor to distinguish bronchitis from pneumonia.
What to Do When a Cold Becomes Bronchitis?
Bronchitis or “chest cold” refers to the inflammation of the airways (bronchial tubes) in the lungs. Air passes through the lungs within a network of tubules called bronchial tubes. Bronchitis is often associated with persistent, nagging coughs with mucus.
What are the Three Major Causes of Pneumonia?
Pneumonia is a lung infection that affects many people. Learn the signs of pneumonia, what causes it, how doctors diagnose it, and what you can do to treat it.
How Do I Know if My Child has Pneumonia?
Pneumonia is a lung infection that affects many children. Learn the signs of pneumonia in children, what causes pneumonia in children, how doctors diagnose pneumonia in children, and what you can do to treat pneumonia in children.
How Do You Know if Your Baby has Bronchitis?
Acute bronchitis, which is sometimes called a chest cold, can develop after your baby has a cold or upper respiratory infection. Bronchitis occurs when the bronchi, the airways that carry air to the lungs, become irritated and inflamed.
What Helps When You Have Bronchitis?
Bronchitis refers to the inflammation of the air-carrying tubes in the lungs (bronchioles). The condition is often associated with persistent, nagging cough with mucus. The condition often starts as an infection of the nose, throat, ears, or sinuses that later moves to the bronchi.
Is Bronchitis Contagious Through Kissing?
Bronchitis is a common issue that affects many people. Learn the signs of bronchitis, what causes it, how doctors diagnose it, and what you can do to treat it.
Treatment & Diagnosis
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- Bronchitis FAQs
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- What Causes an Ear Infection?
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- How Long Is Pneumonia Contagious?
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Medications & Supplements
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Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration.