Does Cefadroxil cause side effects?

Cefadroxil is a cephalosporin antibiotic to treat bacterial infections such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Moraxella catarrhalis, E. coli, Klebsiella, and Proteus mirabilis, urinary tract infections (UTIs), throat infections (sore throat), and tonsillitis

Cephalosporins stop bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together. Bacteria cannot survive without a cell wall. 

Cephalosporins are most effective when bacteria are actively multiplying and forming cell walls. 

Common side effects of cefadroxil include

Serious side effects of cefadroxil include

Drug interactions of cefadroxil include BCG (tuberculosis vaccine) and typhoid live vaccines, because cefadroxil may reduce the immune response to these vaccines and result in less effective vaccination. 

There are no adequate studies of cefadroxil in pregnant women. Cefadroxil is secreted in breast milk. Consult your doctor before breastfeeding

What are the important side effects of Cefadroxil?

Cefadroxil generally is well-tolerated. The most common side effects are:

Patients who have had allergic reactions to other cephalosporins should not take cefadroxil. Additionally, persons allergic to penicillin or one of its derivatives (for example, amoxicillin [Amoxil, Dispermox, Trimox] or ampicillin [Omnipen, Plycillin, Principen]) may also be allergic to cefadroxil, although cefadroxil has been used safely in such patients.

Other important side effects which are serious, but rare include:

  • seizures,
  • severe allergic reactions (anaphylaxis),
  • and reduced platelet or red blood cell counts.

Cefadroxil can alter the normal bacteria in the colon and encourage overgrowth of some bacteria, specifically, Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting cefadroxil (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.

Cefadroxil side effects list for healthcare professionals

Gastrointestinal

Hypersensitivity

Other

What drugs interact with Cefadroxil?

Drug /Laboratory Test Interactions

Positive direct Coombs’ tests have been reported during treatment with the cephalosporin antibiotics. In hematologic studies or in transfusion cross-matching procedures when antiglobulin tests are performed on the minor side or in Coombs’ testing of newborns whose mothers have received cephalosporin antibiotics before parturition, it should be recognized that a positive Coombs’ test may be due to the drug.

Summary

Cefadroxil is a cephalosporin antibiotic to treat bacterial infections such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Moraxella catarrhalis, E. coli, Klebsiella, and Proteus mirabilis, urinary tract infections (UTIs), throat infections (sore throat), and tonsillitis. Common side effects of cefadroxil include diarrhea or loose stools, nausea, abdominal pain, vomiting, and rash. There are no adequate studies of cefadroxil in pregnant women. Cefadroxil is secreted in breast milk.

Treatment & Diagnosis

Medications & Supplements

Prevention & Wellness

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Medically Reviewed on 1/22/2021
References
FDA Prescribing Information

Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration.