Sida Cordifolia

Reviewed on 6/11/2021
Other Name(s):

Abutilon en Épi, Bala, Bariar, Country Mallow, Guimauve, Heartleaf, Herbe de Douze Heures, Indian Chikana, Khareti, Malva Blanca, Malva-Branca, Malva-Branca-Sedosa, Mauve Blanc, Mauve du Pays, Silky White Mallow, Vatya, White Mallow.


Sida cordifolia is a plant. The seeds and root are used to make medicine.

Sida cordifolia contains ephedrine, which is an amphetamine-like stimulant that can cause harmful side effects. Since April 2004 the US Food and Drug Administration (FDA) has banned ephedra, Sida cordifolia, and other products that contain ephedrine.

Despite serious safety concerns, Sida cordifolia is used to treat bronchial asthma, tuberculosis, colds, flu, swine flu, chills, lack of perspiration, headaches, nasal congestion, cough and wheezing, urinary infections, sore mouth, and fluid retention. It is also used for heart disease, stroke, facial paralysis, tissue pain and swelling (inflammation), sciatic nerve pain, insanity, nerve pain, nerve inflammation, ongoing achy joints (chronic rheumatism), and unwanted weight loss.

Some people use Sida cordifolia as a stimulant, painkiller, and tonic; and to increase urine production and raise sexual arousal. It is also used before and after cancer chemotherapy to speed recovery from the treatment.

In herbal combinations, Sida cordifolia is used for weight loss, erectile dysfunction (ED), sinus problems, allergy, throat diseases, asthma, and bronchitis. These combinations are also used to burn fat, increase energy, and promote strong bones.

In combination with ginger, Sida cordifolia root is used for the type of fever that comes and goes.

In combination with milk and sugar, Sida cordifolia root is used for urinary urgency and vaginal discharges.

Sida cordifolia is applied directly to the skin for numbness, nerve pain, muscle cramps, skin disorders, tumors, joint diseases, wounds, ulcers, scorpion sting, snakebite, and as a massage oil.

How does it work?

Sida cordifolia plant contains ephedrine, which is an amphetamine-like stimulant. It is unknown how Sida cordifolia might work for other medicinal uses.


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Uses & Effectiveness

Insufficient Evidence to Rate Effectiveness for...

More evidence is needed to rate the effectiveness of Sida cordifolia for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Side Effects

Sida cordifolia is LIKELY UNSAFE for any use. Sida cordifolia contains ephedrine. Sida cordifolia is banned in the US due to safety concerns. Another herb that contains ephedrine called ephedra is linked to high blood pressure, heart attacks, muscle disorders, seizures, strokes, irregular heartbeat, loss of consciousness, and death. Sida cordifolia might also cause these side effects.

Sida cordifolia might also cause dizziness, restlessness, irritability, insomnia, headache, lack of appetite, nausea, vomiting, flushing, tingling, difficulty urinating, and pounding heartbeat.

Do not use Sida cordifolia with other stimulants such as caffeine. This might increase the chance of having side effects, including life-threatening ones. Sources of caffeine include coffee, tea, kola nut, guarana, and mate.


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Special Precautions & Warnings

Pregnancy and breast-feeding: Sida cordifolia is LIKELY UNSAFE. Do not use.

Chest pain (angina): Sida cordifolia can make angina worse because it stimulates the heart. Sida cordifolia is unsafe for anyone to use, but it is particularly unsafe if you have angina. Do not use.

Anxiety: Sida cordifolia can stimulate the nervous system. Large doses might make anxiety worse. Do not use.

Irregular heartbeat (arrhythmia), rapid heartbeat (tachycardia), heart disease, or heart conditions such as long QT interval syndrome: Because Sida cordifolia stimulates the heart, it might make these conditions worse. Sida cordifolia is unsafe for anyone to use, but it is particularly unsafe if you have an irregular, rapid heartbeat, or heart disease. Do not use.

Diabetes: Sida cordifolia might interfere with blood sugar control, and might worsen high blood pressure and circulatory problems in people with diabetes. Do not use.

Essential tremor: Sida cordifolia might make essential tremor worse due to its stimulant effects. Do not use.

High blood pressure: Sida cordifolia might make high blood pressure worse. Sida cordifolia is unsafe for anyone to use, but it is particularly unsafe if you have high blood pressure. Do not use.

Thyroid problems: There is a concern that Sida cordifolia might stimulate the thyroid and make thyroid problems worse. Do not use.

Kidney stones: The ephedrine in Sida cordifolia might cause kidney stones. This is especially harmful if you already have kidney stones. Do not use.

Glaucoma: Sida cordifolia might make glaucoma worse by causing the pupils to dilate. Do not use.

A tumor on the adrenal gland (pheochromocytoma): Sida cordifolia might make the symptoms of pheochromocytoma worse. Do not use.


Medications that can cause an irregular heartbeat (QT interval-prolonging drugs)Interaction Rating: Major Do not take this combination.

Sida cordifolia can increase the speed of your heartbeat. Taking Sida cordifolia along with medications that can cause an irregular heartbeat might cause serious side effects including heart attack.

Some medications that can cause an irregular heartbeat include amiodarone (Cordarone), disopyramide (Norpace), dofetilide (Tikosyn), ibutilide (Corvert), procainamide (Pronestyl), quinidine, sotalol (Betapace), thioridazine (Mellaril), and many others.

MethylxanthinesInteraction Rating: Major Do not take this combination.

Sida cordifolia can simulate the body. Methylxanthines also stimulate the body. Taking Sida cordifolia with methylxanthines might cause side effects such as jitteriness, nervousness, a fast heartbeat, high blood pressure, and anxiety.

Methylxanthines include aminophylline, caffeine, and theophylline.

Stimulant drugsInteraction Rating: Major Do not take this combination.

Stimulant drugs speed up the nervous system and can make you feel jittery and speed up your heartbeat. Sida cordifolia can also speed up the nervous system. Taking Sida cordifolia along with stimulant drugs might cause serious problems including increased heart rate and high blood pressure. Avoid taking stimulant drugs along with Sida cordifolia.

Some stimulant drugs include diethylpropion (Tenuate), epinephrine, phentermine (Ionamin), pseudoephedrine (Sudafed), and many others.

Dexamethasone (Decadron)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

The body breaks down dexamethasone (Decadron) to get rid of it. Sida cordifolia might increase how quickly the body breaks down dexamethasone (Decadron). By increasing how quickly the body breaks down dexamethasone (Decadron) Sida cordifolia might decrease the effectiveness of dexamethasone (Decadron).

Ergot derivativesInteraction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Sida cordifolia can increase blood pressure. Ergot derivatives can also increase blood pressure. Taking Sida cordifolia with ergot derivatives might increase blood pressure too much.

Some of these ergot derivatives include bromocriptine (Parlodel), dihydroergotamine (Migranal, DHE-45), ergotamine (Cafergot), and pergolide (Permax).

Medications for depression (MAOIs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Sida cordifolia contains chemicals that stimulate the body. Some medications used for depression can increase these chemicals. Taking Sida cordifolia with these medications used for depression might cause too much stimulation. This could cause serious side effects including fast heartbeat, high blood pressure, seizures, nervousness, and others.

Some of these medications used for depression include phenelzine (Nardil), tranylcypromine (Parnate), and others.

Medications for diabetes (Antidiabetes drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.

Sida cordifolia might increase blood sugar. Diabetes medications are used to lower blood sugar. By increasing blood sugar, Sida cordifolia might decrease the effectiveness of diabetes medications. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.

Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.


The appropriate dose of Sida cordifolia depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for Sida cordifolia. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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