- What other names is Serrapeptase known by?
- What is Serrapeptase?
- How does Serrapeptase work?
- Are there safety concerns?
- Are there any interactions with medications?
- Dosing considerations for Serrapeptase.
Serrapeptase is used for painful conditions including back pain, osteoarthritis, rheumatoid arthritis, osteoporosis, fibromyalgia, carpel tunnel syndrome, migraine headache, and tension headache.
It is also used for conditions that involve pain and swelling (inflammation) including sinusitis, laryngitis, sore throat, ear infections, swelling after surgery, swelling of a vein with the formation of a blood clot (thrombophlebitis), and inflammatory bowel disease (IBD) including ulcerative colitis and Crohn's disease.
Some people use serrapeptase for heart disease and "hardening of the arteries" (atherosclerosis).
Women use it for non-cancerous lumpy breasts (fibrocystic breast disease), and nursing mothers use it for breast pain caused by too much milk (breast engorgement).
Other uses include treatment of diabetes, leg ulcers, asthma, and pus accumulation (empyema).
Possibly Effective for...
- Facial swelling after surgery to clear the sinuses.
Insufficient Evidence to Rate Effectiveness for...
- Chronic bronchitis. Developing research suggests that serrapeptase can significantly reduce coughing and thin secretions in people with chronic bronchitis after about 4 weeks of treatment.
- Sinus pain (sinusitis). Early research suggests that people with sinusitis who take serrapeptase have significantly reduced pain, nasal secretions, and nasal obstruction after 3-4 days of treatment.
- Hoarseness (laryngitis). Early research suggests that serrapeptase can significantly reduce pain, secretions, difficulty swallowing, and fever in people with laryngitis after 3-4 days of treatment.
- Sore throat (pharyngitis). Early research suggests that serrapeptase can significantly reduce pain, secretions, difficulty swallowing, and fever in people with sore throat after 3-4 days of treatment.
- Back pain.
- Rheumatoid arthritis.
- Carpel tunnel syndrome.
- Leg ulcers.
- Migraine headache.
- Tension headache.
- Pus accumulation (empyema).
- Fibrocystic breast disease.
- Inflammatory bowel disease (IBD) including ulcerative colitis and Crohn's disease.
- Breast engorgement.
- Heart disease.
- Ear infections.
- Other conditions.
Special Precautions & Warnings:Pregnancy and breast-feeding: Not enough is known about the use of serrapeptase during pregnancy and breast-feeding. Stay on the safe side and avoid use.
Bleeding disorders: Serrapeptase might interfere with blood clotting, so some researchers worry that it might make bleeding disorders worse. If you have a bleeding disorder, check with your healthcare provider before using serrapeptase.
Surgery: Serrapeptase might interfere with blood clotting. There is a concern that it might increase bleeding during and after surgery. Stop using serrapeptase at least 2 weeks before a scheduled surgery.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.
Serrapeptase might decrease blood clotting. Therefore, taking serrapeptase along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
- For reducing swelling of the inside of the cheek after sinus surgery: 10 mg of serrapeptase 3 times on the day before surgery, once in the evening after surgery, and then 3 times daily for 5 days following surgery.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
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