- What is sennosides A&B-oral tablet, and how does it work (mechanism of action)?
- What brand names are available for sennosides A&B-oral tablet?
- Is sennosides A&B-oral tablet available as a generic drug?
- Do I need a prescription for sennosides A&B-oral tablet?
- What are the side effects of sennosides A&B-oral tablet?
- What is the dosage for sennosides A&B-oral tablet?
- Which drugs or supplements interact with sennosides A&B-oral tablet?
- Is sennosides A&B-oral tablet safe to take if I'm pregnant or breastfeeding?
- What else should I know about sennosides A&B-oral tablet?
What is sennosides A&B-oral tablet, and how does it work (mechanism of action)?
Senna is a natural medicine derived from the senna plant. Senna contains sennosides which acts as a stimulant laxative. It works by irritating and stimulating intestinal cells, producing contractions in intestines, water influx to the intestines and bowel movement.
What are the side effects of sennosides A&B-oral tablet?
Side effects of sennosides are:
- abdominal pain,
- diarrhea,
- electrolyte imbalance,
- nausea,
- urine discoloration, and
- finger clubbing from long-term use.
What is the dosage for sennosides A&B-oral tablet?
- Adults and children 12 years of age and over: The recommended starting dose is to use two 8.6 mg tablets by mouth once a day; maximum daily dose is 100 mg.
- Children 6 to 12 years of age: The recommended starting dose is to use one 8.6 mg by mouth once a day; maximum daily dose 50 mg a day.
- Children 2 to 6 years of age: The recommended dose is 4.3 to 17.2 mg per day.
- Safe and effective use of sennosides is not established in children younger than 2 years of age.
Which drugs or supplements interact with sennosides A&B-oral tablet?
Sennosides should be cautiously in patients taking digoxin (Lanoxin). Sennosides can lower potassium levels, causing digoxin toxicity.

QUESTION
According to the USDA, there is no difference between a “portion” and a “serving.” See AnswerIs sennosides A&B-oral tablet safe to take if I'm pregnant or breastfeeding?
There are no adequate studies done on sennosides to determine safe and effective use in pregnant women.
It is not known whether sennosides enters breast milk; therefore, it is best to be cautious before using it in nursing mothers.
What else should I know about sennosides A&B-oral tablet?
What preparations of sennosides A&B-oral tablet are available?
Tablets: 8.6, 15, 25 mg; Chewable Tablet: 10, 15 mg; Liquid or Syrup: 8.8 mg/5 ml; Concentrated oral drops: 8.8 mg/ml
How should I keep sennosides A&B-oral tablet stored?
Store sennosides tablets between 15 C to 30 C (59 F to 86 F).
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Summary
Senna (sennosides; Senokot, Senokot EXTRA, and others) is a natural medicine used to treat constipation. Side effects, drug interactions, dosage, and pregnancy safety information should be reviewed prior to taking this supplement.
Related Disease Conditions
-
Irritable Bowel Syndrome (IBS)
Irritable bowel syndrome or IBS is a GI disorder with symptoms of constipation, abdominal pain, bloating, and gas. IBS treatment includes medications, dietary changes, and lifestyle changes.
-
Constipation
Constipation is defined medically as fewer than three stools per week and severe constipation as less than one stool per week. Constipation usually is caused by the slow movement of stool through the colon. There are many causes of constipation including medications, poor bowel habits, low-fiber diets, laxative abuse, and hormonal disorders, and diseases primarily of other parts of the body that also affect the colon.
-
Laxatives for Constipation
Laxatives types for the treatment of constipation include over-the-counter (OTC) preparations, for example, bulk-forming laxatives, stool softeners, lubricant laxatives, stimulants, or saline laxatives, enemas, and suppositories.
-
Melanosis Coli
Melanosis coli is a condition that is often associated with prolonged laxative use. Dark pigment forms in the wall of the large intestine as a result of wear and tear. Melanosis coli (pseudomelanosis coli) causes no symptoms and can be reversed with discontinuation of laxative use.
Treatment & Diagnosis
Medications & Supplements
Prevention & Wellness

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REFERENCES:
MedscapeReference. Constipation Medication.
MedlinePlus. Senna.