senna (sennosides)

What is sennosides A&B-oral tablet, and how does it work (mechanism of action)?

Senna is a natural medicine derived from the senna plant. Senna contains sennosides which acts as a stimulant laxative. It works by irritating and stimulating intestinal cells, producing contractions in intestines, water influx to the intestines and bowel movement.

What brand names are available for sennosides A&B-oral tablet?

Senokot, Senokot EXTRA and others

Is sennosides A&B-oral tablet available as a generic drug?


Do I need a prescription for sennosides A&B-oral tablet?


What are the side effects of sennosides A&B-oral tablet?

Side effects of sennosides are:

What is the dosage for sennosides A&B-oral tablet?

  • Adults and children 12 years of age and over: The recommended starting dose is to use two 8.6 mg tablets by mouth once a day; maximum daily dose is 100 mg.
  • Children 6 to 12 years of age: The recommended starting dose is to use one 8.6 mg by mouth once a day; maximum daily dose 50 mg a day.
  • Children 2 to 6 years of age: The recommended dose is 4.3 to 17.2 mg per day.
  • Safe and effective use of sennosides is not established in children younger than 2 years of age.

Which drugs or supplements interact with sennosides A&B-oral tablet?

Sennosides should be cautiously in patients taking digoxin (Lanoxin). Sennosides can lower potassium levels, causing digoxin toxicity.


According to the USDA, there is no difference between a “portion” and a “serving.” See Answer

Is sennosides A&B-oral tablet safe to take if I'm pregnant or breastfeeding?

There are no adequate studies done on sennosides to determine safe and effective use in pregnant women.

It is not known whether sennosides enters breast milk; therefore, it is best to be cautious before using it in nursing mothers.

What else should I know about sennosides A&B-oral tablet?

What preparations of sennosides A&B-oral tablet are available?

Tablets: 8.6, 15, 25 mg; Chewable Tablet: 10, 15 mg; Liquid or Syrup: 8.8 mg/5 ml; Concentrated oral drops: 8.8 mg/ml

How should I keep sennosides A&B-oral tablet stored?

Store sennosides tablets between 15 C to 30 C (59 F to 86 F).


Senna (sennosides; Senokot, Senokot EXTRA, and others) is a natural medicine used to treat constipation. Side effects, drug interactions, dosage, and pregnancy safety information should be reviewed prior to taking this supplement.

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Medically reviewed by John P. Cunha, DO, FACOEP; Board Certified Emergency Medicine


MedscapeReference. Constipation Medication.

MedlinePlus. Senna.