Self-neglect implies the inability or unwillingness to attend to one's personal needs or hygiene. It may manifest in different ways, such as not attending to one's nutrition, hygiene, clothing, or acting appropriately to care for medical conditions. Self-neglect can occur as a result of dementia, brain damage, or mental illnesses like depression or psychotic disorders. Some people who suffer from self-neglect may engage in unhealthy behaviors such as substance use or abuse, tobacco use, promiscuity, or inappropriate use of prescription medications. The list of conditions associated with self-neglect is very broad, and treatment options depend upon the precise cause of self-neglect. Antipsychotic and antidepressant medications are used when certain mental illnesses are the cause. Extreme self-neglect has been referred to as Diogenes syndrome.
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.
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Examples of Medications for Self-Neglect
- aripiprazole (Abilify, Abilify Maintena, Aristrada)
- bupropion (Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zyban, Aplenzin, Fortivo XL, Zyban)
- chlorpromazine - oral, Thorazine
- chlorpromazine-injection, Thorazine
- citalopram, Celexa
- clozapine (Clozaril, Fazacio ODT, Versacloz)
- desvenlafaxine (Pristiq, Khedezla)
- duloxetine, Cymbalta
- fluoxetine, Prozac, Sarafem, Prozac Weekly
- fluphenazine (Permitil, Prolixin)
- fluphenazine concentrate - oral, Prolixin
- fluphenazine liquid - oral, Prolixin
- fluvoxamine (Luvox and Luvox CR have been discontinued)
- haloperidol (Haldol)
- lamotrigine, Lamictal, Lamictal CD, Lamictal ODT, Lamictal XR
- Lexapro (escitalopram)
- lithium, Lithobid
- mirtazapine (Remeron, Soltab)
- nefazodone, Serzone
- olanzapine, Zyprexa, Zydis, Zyprexa Relprevv
- paroxetine, Paxil, Paxil CR, Pexeva
- quetiapine (Seroquel, Seroquel XR)
- risperidone, Risperdal; Risperdal Consta, Risperdal M-TAB
- Sertraline (Zoloft)
- thiothixene - oral, Navane
- trazodone (Desyrel - discontinued brand)
- valproic acid, divalproex, Depakote, Depakote Sprinkle, Depakote ER, Depakene, Depacon, Stavzor
- venlafaxine, Effexor XR (Effexor has been discontinued in the US)
- ziprasidone (Geodon)