What is the treatment for melioidosis?
The treatment of melioidosis involves antibiotics and depends on the location of the disease.
For patients with more mild illness, the CDC recommends medication with antibiotics such as imipenem, meropenem (Merrem), penicillin, doxycycline (Doryx, Oracea, Monodox), amoxicillin-clavulanic acid (Augmentin, Augmentin XR), ceftazidime (Fortaz, Tazicef), ticarcillin-clavulanic acid (Timentin), ceftriaxone (Rocephin), and aztreonam (Cayston, Azactam). Patients who are more severely ill are given a combination of two of the above medications for three to six months.
After the initial intensive therapy, eradication therapy may be initiated using trimethoprim-sulfamethoxazole (Bactrim, Sulfatrim).
With pulmonary involvement of melioidosis, if cultures remain positive for six months, surgical removal of the lung abscess with lobectomy is considered.