Share your story with others:

MedicineNet appreciates your comment. Your comment may be displayed on the site and will always be published anonymously. Patient Comments FAQs

Tell us a bit about your background to make your comments more useful to other MedicineNet users.

Screen Name: *

Gender of Patient:Male Female

Age Range of Patient:

I am a: Patient Caregiver

Enter your Comment

* Screen Name will appear next to the published comment. Please do not include your full name or email address.

By submitting your comment, and other materials (collectively referred to as a "Submission") to MedicineNet, you grant MedicineNet permission to use, copy, transmit, publish, display, edit and modify your Submission in connection with its Web site. MedicineNet will not pay you for your Submission. You represent that you have all rights necessary for MedicineNet to use your Submission as set forth above.

Please keep these guidelines in mind when writing your comment:

  • Please make sure you address the question asked.
  • Due to the overwhelming number of comments received, not all comments will be published.
  • When selecting comments to publish, our staff will choose those that are educational and complement the topic. Please try to stay on topic.
  • Your comment may be edited. We would typically edit comments to make them clearer and more readable. We will remove personal information such as last names, email and web addresses, and other potentially harmful information.
  • We will not notify you if your comment has been published. We suggest that you check back on the topic article regularly.
  • We do not provide medical or healthcare advice, treatment, or diagnosis.

Thank you for participating!

I have read and agree to abide by the MedicineNet Terms and Conditions and the MedicineNet Privacy Policy (required).

To prevent our systems from spam, please complete the following prior to submitting your comment.

Which diuretics are used to treat edema?

Edema can become a problem in systemic diseases of the heart, liver or kidneys. Diuretic therapy can be initiated, often alleviating the edema. The most potent diuretics are loop diuretics, so-called because they work in the portion of the kidney tubules referred to as the loop of Henle. The kidney tubules are small ducts that regulate salt and water balance, while transporting the forming urine. Clinical loop diuretics available are:

  • furosemide (Lasix),
  • torsemide (Demadex),
  • butethamine (Bumex),
  • ethacrynate (Edecrin)

The doses of these diuretics vary depending upon the patient's clinical circumstances. These drugs can be given orally, although seriously ill patients in the hospital may receive them intravenously for more prompt or effective response. If one of the loop diuretics is not effective alone, it may be combined with an agent that works further down (more distally) in the tubule. These agents include the thiazide type diuretics, such as hydrochlorothiazide (HydroDIURIL), or a similar but more potent type of diuretic called metolazone (Zaroxolyn). Other thiazide diuretics include chlorthalidone (Thalitone) methyclothiazide (enduron), chlorthalidone (Hygroton), indapamide (Lozol), and metolazone (Zaroxolyn, Diulo, Mykrox). When diuretics that work at different sites in the kidney are used together, the response often is greater than the combined responses to the individual diuretics (synergistic response).

Return to Edema

See what others are saying

Comment from: J Smith, 45-54 Male (Patient) Published: August 01

I had edema in my legs for a few years, and it had gotten to the point that I could not stand up (or even sit down) and work for more than a few hours. Even my fingers were a bit puffy, as I couldn't get my wedding ring off most days. The wife was concerned, as she'd seen it in the nursing home where she used to work, and said it may be a sign of impending heart problems. I tried reducing my salt intake (nothing). I tried doing green tea (a known diuretic), still nothing. Support stockings were my only option at that point. I had gained quite a bit of weight a few year earlier, as I had quit smoking cigarettes, and started eating cheesecakes. I decided to lose some weight by doing a ketogenic diet about nine months ago. To date I've lost about 75 pounds, and pretty much all/most of the edema in my legs are gone! Now weight lost may have been a big factor, but I'm convinced, after reading the actual research on PubMed and other sources, it was the excess carbohydrates that was making my blood pressure so high, and causing the edema. I know this because it took 4 or 5 months for most of the edema to disappear, but it took less than a month for my blood pressure (BP) to drop 20 points on the systolic (lower BP means less fluid retention). Now 129/72 is the reading my wife just took (was upwards of 156/95 before diet). Interestingly since I started this LCHF (low-carb, high fat) diet I routinely drink upwards of 12 plus eight ounces of water a day (the liver requires a lot of water to make ketones on this diet). So, much more water intake, lower BP, and the edema disappeared too. Oh by the way, I'm eating upwards of 4 or 5 grams of salt per day to boot (again, something this diet requires is more salt intake). So this proves that salt is not the culprit everyone says it is for high BP. Sure, it can exacerbate it if you already have high BP, but it is not the main driver of it.

Was this comment helpful?Yes
Comment from: 35-44 Female (Caregiver) Published: August 01

My mother has had pitting edema since as long as I can remember, in short she's done everything, only relief for her was grapes. Every day 2 to 3 hundred gram grapes worked for her. Even missing to take grapes for a few days makes it severe.

Was this comment helpful?Yes
Comment from: mystycal1, 45-54 Female (Patient) Published: July 31

I got edema as a side effect to prednisone, Symbicort and gabapentin; just for your information. I get acupuncture and see a chiropractor and it is almost gone.

Was this comment helpful?Yes

Health Solutions From Our Sponsors