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What medications treat diarrhea (IBS-D) and constipation (IBS-D) in irritable bowel syndrome?

Diarrhea medicine for IBS

  • Antidiarrheal medications such as loperamide (Imodium), attapulgite (Kaopectate), and diphenoxylate and atropine (Lomotil) can be helpful if loose stools are one of the main signs. Eluxadoline (Viberzi) is a prescription for the treatment of irritable bowel syndrome with diarrhea (IBS-D).
  • For females with IBS who experience severe diarrhea, alosetron (Lotronex) has been used.
  • Rifaximin (Xifaxan) is an antibiotic for the treatment of irritable bowel syndrome with diarrhea (IBS-D) and IBS-related bloating.
  • Bile acid binders including cholestyramine ( (Prevalite), colestipol (Colestid), or colesevelam (Welchol) can help some patients with IBS-D, but can also cause bloating.

Constipation medication for IBS

  • Over-the-counter laxatives such as polyethylene glycol 3350 ( (MiraLAX), bisacodyl (Dulcolax), and psyllium seed husks (Metamucil) can help relieve constipation and keep bowel movements regular. Senna laxatives (Senokot, Ex-Lax Gentle Nature) may be taken short-term. Prescription laxatives such as lactulose (Constulose) may also be prescribed.
  • Two drugs specifically used to treat IBS are lubiprostone (Amitiza), a laxative, and linaclotide (Linzess), a constipation medication.
  • SSRI antidepressants fluoxetine (Prozac), citalopram (Celexa), sertraline (Zoloft), paroxetine (Paxil), and escitalopram (Lexapro) may be helpful for those with constipation (IBS-C), but they can trigger IBS attacks in patients with diarrhea (IBS-D).
Return to Irritable Bowel Syndrome (IBS)

See what others are saying

Comment from: sacha, 45-54 Male (Patient) Published: November 30

I have been taking Morease for the last one month for IBS (irritable bowel syndrome) along with VSL3. It improved a lot.

Was this comment helpful?Yes
Comment from: Archit, Male (Caregiver) Published: December 10

Arogyam pure herbs kit helps cure irritable bowel syndrome (IBS) without any side effects.

Was this comment helpful?Yes

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