Medical Definition of Paleostriatum

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Paleostriatum: A pale-appearing spherical area in the brain. The paleostriatum is specifically part of what is called the lentiform nucleus which, in turn, is part of the striate body, a component of the basal ganglia, large masses of gray matter at the base of the cerebral hemispheres of the brain.

Cells within the paleostriatum may be preferentially damaged and perish in carbon monoxide poisoning, barbiturate intoxication, cyanide poisoning, hydrogen sulfide poisoning, profound prolonged hypoglycemia, hypoxia, hypotension, and Wilson disease.

Paleostriatum means old stratum. It was so named because it was thought to have evolved before the neostriatum (the new stratum), a different part of the striate body of the brain.

The paleostriatum is also called the globus pallidus, globus being the Latin for globe and pallidus referring to its pallor.

Reviewed on 9/7/2018

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