Medical Definition of Phosphatase, alkaline

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Phosphatase, alkaline: An enzyme that liberates phosphate under alkaline conditions and is made in liver, bone, and other tissues. Alkaline phosphatase can be measured in a routine blood test. Abnormally high serum levels of alkaline phosphatase may indicate bone disease, liver disease, or bile duct obstruction.

Reviewed on 9/7/2018

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