Medical Definition of Glucuronosyltransferase, UDP-

  • Medical Author:
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Glucuronosyltransferase, UDP-: A liver enzyme essential to the disposal of bilirubin (the chemical that results from the normal breakdown of hemoglobin from red blood cells). The enzyme is responsible for what is called the glucuronidation reaction. UDP acts as a catalyst for the transfer of the glucuronic acid component of UDP-glucuronic acid to a substrate molecule. The resulting glucuronide is more easily eliminated from the body by the kidneys into the urine.

See: Deficiency, UDP-glucuronosyltransferase, Gilbert's Disease.

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Reviewed on 12/27/2018

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