Medical Definition of Yellow enzyme, Warburg's

  • Medical Author:
    Melissa Conrad Stöppler, MD

    Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Yellow enzyme, Warburg's: A key respiratory enzyme discovered by the German biochemist Otto Heinrich Warburg (1883-1970), a pioneer in research on the respiration of cells and the metabolism of tumors. Warburg's yellow enzyme is a flavoprotein that catalyzes an oxidation-reduction reaction necessary for normal breathing (respiration) , in other words, use of oxygen by cells.

Warburg won the Nobel Prize in physiology or medicine in 1931 "for his discovery of the nature and mode of action of the respiratory enzyme."

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Reviewed on 12/27/2018

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