Medical Definition of Osler's nodes
Osler's nodes: These are small (the size of split peas), tender, transient nodules in the pads of fingers and toes and the palms and soles. They are a highly diagnostic sign of bacterial infection of the heart (subacute bacterial endocarditis). Named for the Canadian-born physician Sir William Osler (1849-1919).
Quick GuideHeart Disease: Causes of a Heart Attack
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