Medical Definition of Aminotransferase

  • Medical Author:
    William C. Shiel Jr., MD, FACP, FACR

    Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Aminotransferase: An enzyme that catalyzes the transfer of an amino group from a donor molecule to a recipient molecule. The donor molecule is usually an amino acid and the recipient molecule is usually an alpha-2 keto acid. Two of the best-known enzymes in this class are serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT), both of which are normally found primarily in cells in the liver and heart.

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Reviewed on 12/27/2018

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